A5079951344- Trypanosoma species research and implications
- Research on Leishmaniasis Studies
- Cell Adhesion Molecules Research
- Clinical Nutrition and Gastroenterology
- Neurogenesis and neuroplasticity mechanisms
- Cancer-related gene regulation
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Reproductive tract infections research
- NF-κB Signaling Pathways
- Animal Genetics and Reproduction
- Plant Virus Research Studies
- TGF-β signaling in diseases
- Streptococcal Infections and Treatments
- Peptidase Inhibition and Analysis
- Pneumonia and Respiratory Infections
- Cervical Cancer and HPV Research
- Environmental Sustainability and Education
- Lysosomal Storage Disorders Research
- Enhanced Recovery After Surgery
- Neonatal and Maternal Infections
- Antifungal resistance and susceptibility
- Hippo pathway signaling and YAP/TAZ
- Gastrointestinal motility and disorders
- Asthma and respiratory diseases
Universidade de São Paulo
2007-2022
ABSTRACT The flagellum and attachment zone (FAZ) are important cytoskeletal structures in trypanosomatids, being required for motility, cell division morphogenesis. Trypanosomatid cytoskeletons contain abundant high molecular mass proteins (HMMPs), but many of their biological functions still unclear. Here, we report the characterization giant FAZ protein, FAZ10, Trypanosoma brucei, which, using immunoelectron microscopy, show localizes to intermembrane staples intracellular domain. Our data...
PURPOSE: To characterize of the intestinal microbiota patients with short bowel syndrome (SBS) admitted to Metabolic Unit a University Hospital. METHODS: Fecal samples were evaluated, and biochemical tests conducted only in case SBS patients. The nutritional status was assessed via anthropometric measurements evaluation food intake by means questionnaire. pathogenic strains detected aid cultures specific aerobic medium, for determination species belonging Family enterobacteriaceae. Anti-sera...
Oral squamous cell carcinoma (OSCC) remains a challenging cancer to treat despite all the advances of last 50 years. Kallikrein 5 (KLK5) is among serine proteases implicated in OSCC development. However, whether activity KLK5 promotes carcinogenesis still controversial. Moreover, knowledge regarding role cognate inhibitor, Lympho-Epithelial Kazal-Type related Inhibitor (LEKTI), scarce. We have, thus, sought investigate importance and LEKTI expression premalignant malignant lesions oral...
Host manipulation is a common strategy for invading pathogens. Trypanosoma cruzi, the causative agent of Chagas Disease, lives intracellularly within host cells. During infection, parasite-associated modifications occur to cell metabolism and morphology. However, little known about effect T. cruzi infection on nucleus nuclear functionality. Here, we show that can modulate transcription splicing machinery in non-professional phagocytic cells during infection. We found regulates RNA polymerase...
Head and neck squamous cell carcinoma remains challenging to treat with no improvement in survival rates over the past 50 years. Thus, there is an urgent need discover more reliable therapeutic targets biomarkers for HNSCC. Matriptase, a type-II transmembrane serine protease, induces malignant transformation epithelial stem cells through proteolytic activation of pro-HGF PAR-2, triggering PI3K-AKT-mTOR NFKB signaling. The protease inhibitor lympho-epithelial Kazal-type-related (LEKTI)...
Vulvovaginal candidiasis is an opportunistic infection that affects most women in adult life, but the defense mechanism remains to be elucidated. Animals treated with estradiol were inoculated Candida albicans having high virulence power. The experimental control consisted of animal groups and animals without treatment physiologic serum. vaginal wall was collected, at different times. material destined counting Colony Forming Units (CFU), detection PGE2, IgE histological staining...
O trabalho apresenta estrategias utilizadas para a sensibilizacao ambiental de uma comunidade universitaria pertencente Universidade Sao Paulo (USP), embasadas por principios que buscam desenvolver acoes conservacao dos recursos naturais da Universidade; promover um ambiente saudavel e seguranca ambiental; o uso racional e; educar visando sustentabilidade. Nesse sentido, Faculdade Medicina Ribeirao Preto, USP campus instituiu Comissao Gestao Ambiental, subdividida em grupos (GT-PGRSS;...