Elisabetta Goni
- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Helicobacter pylori-related gastroenterology studies
- IgG4-Related and Inflammatory Diseases
- Gastric Cancer Management and Outcomes
- Liver Disease Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Gastroesophageal reflux and treatments
- Neuroendocrine Tumor Research Advances
- Genetic factors in colorectal cancer
- Diverticular Disease and Complications
- Gallbladder and Bile Duct Disorders
- Diabetes and associated disorders
- Gastrointestinal motility and disorders
- Metastasis and carcinoma case studies
- Eosinophilic Esophagitis
- Cancer Genomics and Diagnostics
- Caveolin-1 and cellular processes
- Immunodeficiency and Autoimmune Disorders
- Colorectal Cancer Screening and Detection
- Microbial Metabolites in Food Biotechnology
- Veterinary medicine and infectious diseases
- Gastrointestinal Tumor Research and Treatment
- Clinical Nutrition and Gastroenterology
- Nutritional Studies and Diet
Ludwig-Maximilians-Universität München
2018-2024
LMU Klinikum
2018-2024
Otto-von-Guericke University Magdeburg
2015-2017
University Hospital Magdeburg
2015-2017
Istituti di Ricovero e Cura a Carattere Scientifico
2016
Vita-Salute San Raffaele University
2012-2016
University of Parma
2012-2015
Ospedale Maggiore
2014
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2014
Ospedale di Parma
2014
Background and aims Autoimmune pancreatitis (AIP) is an immune-mediated disease of the pancreas with distinct pathophysiology manifestations. Our were to characterize type 1 AIP in a large pan-European cohort study effectiveness current treatment regimens. Methods We retrospectively analyzed adults diagnosed since 2005 or not-otherwise-specified 42 European university hospitals. Type was uniformly using specific diagnostic criteria. Patients 2 those who had undergone pancreatic surgery...
Objectives Patients with autoimmune gastritis (AIG) are reported to have an increased risk of developing gastric cancer (GC). In this study, we assess the characteristics and outcomes GC patients AIG in a multicenter case‐control study. Methods Between April 2013 May 2017, GC, including cancers esophagogastric junction (EGJ) Siewert type II III, were recruited. histological identified matched 1:2 fashion for age gender no AIG. Presenting symptoms documented using self‐administered...
Diverticular Inflammation and Complication Assessment (DICA) endoscopic classification has been recently developed for patients suffering from diverticulosis diverticular disease.We assessed retrospectively the predictive value of DICA in whom data clinical follow-up were available.For each patient, we recorded: age, severity DICA, presence abdominal pain, C-reactive protein faecal calprotectin test (if available) at time diagnosis; months follow-up; therapy taken during to maintain...
Pancreatic ductal adenocarcinoma cancer (PDAC) is a highly lethal malignancy requiring efficient detection when the primary tumor still resectable. We previously developed MxPancreasScore comprising 9 analytes and serum carbohydrate antigen 19-9 (CA19-9), achieving an accuracy of 90.6%. The necessity for 5 different analytical platforms multiple runs, however, hindered clinical applicability. therefore aimed to develop simpler single-analytical run, single-platform diagnostic signature.We...
In pancreatic cancer, systemic treatment options in addition to chemotherapy remain scarce, and so far only a small proportion of patients benefit from targeted therapies.The with cancer discussed the CCCMunichLMU Molecular Tumor Board were reviewed gain better real-world understanding challenges chances precision oncology this hard-to-treat cancer.Patients who received comprehensive genomic profiling interdisciplinary between May 2017 July 2022 included. These patients' medical charts,...
Digital single-operator pancreatoscopy (DSOP)-guided lithotripsy is a novel treatment modality for pancreatic endotherapy, with demonstrated technical success in retrospective series of between 88 % and 100 %. The aim this prospective multicenter trial was to systematically evaluate DSOP patients chronic pancreatitis symptomatic duct stones.Patients three or fewer stones ≥ 5mm the main (MPD) head body were included. primary end point complete stone clearance (CSC) sessions DSOP. Current...
With the rising importance of precision oncology in biliary tract cancer (BTC), aim this retrospective single-center analysis was to describe clinical and molecular characteristics patients with BTC who underwent comprehensive genomic profiling (CGP) were discussed CCCMunichLMU tumor board (MTB).In observational study, we included intrahepatic cholangiocarcinoma (iCCA), extrahepatic CCA (eCCA), gallbladder (GB), had been institutional MTB from May 29, 2017, July 25, 2022. Patients followed...
The usefulness of cardiovascular disease (CVD) predictive equations in different populations is debatable. We assessed the efficacy Framingham-REGICOR scale, validated for Spanish population, to identify future CVD participants, who were predefined as being at high-risk PREvención con DIeta MEDiterránea (PREDIMED) study-a nutrition-intervention primary prevention trial-and impact adherence Mediterranean diet on across risk categories.In a post hoc analysis, we value baseline estimated 5966...
Early-onset colorectal cancer (eoCRC), defined as a (CRC) in patients younger than 50 years old, shows an increasing incidence worldwide the latest years. The role of exogenous factors associated with CRC has been largely overlooked eoCRC. Here, we conducted case-control study to evaluate diet and lifestyle habits Italian population eoCRC, compared age-matched healthy controls (HCs).We enrolled 118 subjects (47 cases, 71 controls) third-level academic hospital. We analyzed epidemiological...
Severity of microlithiasis- and sludge-induced pancreatitis in comparison to gallstone-induced has never been studied for a lack definition.
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers. Developing biomarkers for early detection and chemotherapeutic response prediction crucial to improve dismal prognosis PDAC patients. However, molecular cancer signatures based on transcriptome analysis do not reflect intratumoral heterogeneity. To explore a more accurate stratification phenotypes in an easily accessible matrix, plasma metabolome using MxP® Global Profiling Lipidomics was performed 361 We identified...
<b><i>Aims:</i></b> The acute respiratory distress syndrome (ARDS) is a frequent condition following pneumonia in immunocompromised cancer patients. Extracorporeal membrane oxygenation (ECMO) may serve as rescue therapy refractory ARDS but has still not been studied predominantly leuco- and thrombocytopenic <b><i>Patients Methods:</i></b> In this monocentric, retrospective, observational study, we assessed all patients treated with ECMO for...
The segmental colitis associated with diverticulosis," better known by its acronym "SCAD," is a chronic inflammatory process localized in the colonic area presenting diverticulosis, and therefore mainly sigmoid colon. By definition, both rectum right colon are spared from any inflammation endoscopically histologic point of view. Recent data have hypothesized that SCAD may be an independent clinical entity within bowel disease set diseases. Compared disease, seems to more benign outcome, low...
The aim of this study was to investigate the contribution smoking and alcohol intake pancreas divisum on risk developing chronic pancreatitis (CP).Consecutive patients with CP who underwent secretin-enhanced magnetic resonance cholangiopancreatography were compared consecutive without pancreatic disease for irritable bowel syndrome.We enrolled 145 103 syndrome from 2010 2014. In a univariate analysis, statistically significant differences in sex, mean age, duration amount cigarette use...