A5100428740- Nanoplatforms for cancer theranostics
- Pesticide and Herbicide Environmental Studies
- Analytical chemistry methods development
- Nanoparticle-Based Drug Delivery
- Pesticide Exposure and Toxicity
- Heavy Metal Exposure and Toxicity
- Advanced Sensor and Energy Harvesting Materials
- Environmental Toxicology and Ecotoxicology
- Urban Heat Island Mitigation
- Blood disorders and treatments
- Influenza Virus Research Studies
- Smart Materials for Construction
- Birth, Development, and Health
- Trace Elements in Health
- Bacterial Identification and Susceptibility Testing
- Methane Hydrates and Related Phenomena
- Neutropenia and Cancer Infections
- Adsorption and biosorption for pollutant removal
- Wastewater Treatment and Nitrogen Removal
- Building Energy and Comfort Optimization
- Advanced Nanomaterials in Catalysis
- Orbital Angular Momentum in Optics
- Forensic Toxicology and Drug Analysis
- Electrical and Thermal Properties of Materials
- Cervical and Thoracic Myelopathy
First Hospital of Qinhuangdao
2016-2025
Yanshan University
2020-2024
State Key Laboratory of Metastable Materials Science and Technology
2020-2024
Shengli Oilfield Central Hospital
2024
Yunnan Open University
2023
Chengde Medical University
2023
Liaoning Normal University
2007-2023
Shanghai University of Traditional Chinese Medicine
2023
Second Military Medical University
2023
Shanghai University
2023
Glyphosate (GLY) is the most widely used broad-spectrum, non-selective herbicide in world, whose main degradation product aminomethyl phosphonic acid (AMPA). Because of long-term and large-scale use, residual GLY AMPA environment pose great environmental human health threats. The purpose this study to evaluate effects mechanism low-concentrations on development zebrafish embryos. Zebrafish embryos were exposed 0, 1, 10, 100, 700 ng·mL-1 for 72 h (from 2 74 post-fertilization). With...
Multifunctional nanomedicines for tumor therapy have received more and attention. Here, we developed a tumor-targeting pH/near-infrared (NIR) dual stimulus-responsive nanodrug delivery system (PDA-Au@HA/DOX). Hyaluronic acid (HA) was decorated on the nanoparticle surface, which endowed with properties by specifically binding CD44 receptor overexpressed in various cells. The excellent photothermal performance of polydopamine (PDA) gold nanoshells under NIR irradiation could destroy cells one...
Following the publication of above paper, it was drawn to Editor's attention by a concerned reader that certain JNK and phosphorylated (pho)‑JNK western blotting data shown in Fig. 8 on p. 7 were strikingly similar featured pair other articles written different authors at research institutes, one which (submitted journal Molecular Medicine Reports) has been subsequently retracted, whereas Renal Failure) received prior receipt article International Journal Medicine. In view fact...
Detailed mechanism of <italic>cis</italic>-BR cross-linking with peroxides was studied using PCMD2D and 2D correlation FTIR, a 5-step process determined.
A bench‐scale, pipe section reactor (PSR) was developed and tested to measure the decay rate of chlorine (Cl 2 ) at wall, commonly described as “wall demand” but herein referred chlorine–wall reaction. This experimental protocol is more convenient than loop reactors that require a large laboratory volume water. The design allows investigation effect velocity on Two 6‐in. (152‐mm) diameter sections old cast‐iron (CI) new cement‐lined ductile‐iron (DI) were used. In addition water velocity,...
Epidemiologic studies demonstrated that the environment serves a crucial role in cancer development. Heavy metals, including arsenic (As), cadmium (cd), chromium (Cr), lead and mercury, are considered to be carcinogens or co‑carcinogens. Furthermore, Cd has been detected breast (BC) tissue at high concentrations. The present study aimed investigate correlation between heavy metals urine metabolome of patients with BC, their association Nuclear magnetic resonance was used determine...
Clearance of endogenous glutathione (GSH) to cytotoxic hydroxyl radicals (•OH) and insufficient cellular hydrogen peroxide (H2O2) limited the efficacy chemodynamic therapy (CDT) a tumor. Herein, biocompatible nanosystem has been developed overcome dilemma CDT; first, soya lecithin, paclitaxel, MnO2 nanoparticles, glucose oxidase (GOx) were self-assembled PTX/MnO2/GOx-Lips then hyaluronic acid (HA) was modified on surface enhance tumor targeting. consumed GSH generate Mn2+, which relieved...
Zinc oxide nanoparticles (ZnO NPs), known for their chemical stability and strong adsorption, are used in everyday items such as cosmetics, sunscreens, prophylactic drugs. However, they have also been found to adversely affect organisms; previously we that ZnO NPs disrupt pubertal ovarian development, inhibit embryonic development by upsetting -H2AX NF-B pathways, even disturb skin stem cells. Non-targeted metabolomic analysis of biological organisms has suggested an unbiased tool the...
Abstract Background The poor targeting delivery efficiency and limited efficacy of single therapeutic approach have consistently posed significant challenges in tumor management. Results In this research, we conceived synthesized a dual-targeting nanodrug system denoted as PDA-DEM-Fe 3 O 4 @M, which incorporates polydopamine nanoparticle (PDA) with photothermal properties, diethyl maleate (DEM) chemotherapy agent accelerating apoptosis, iron oxide nanoparticles (Fe ) eliciting magnetic...
The toxicity of chloroacetamide herbicide in embryo development remains unclear. Acetochlor (AC) is a that metabolizes into 2‑ethyl‑6‑methyl-2-chloroacetanilide (CMEPA) and 6‑ethyl‑o‑toluidine (MEA). present study determined the potential effect AC its metabolites on development. Both HepG2 cells zebrafish embryos were exposed to AC, CMEPA MEA presence or absence co‑treatment with anti‑reactive oxygen species (ROS) reagent N‑acetylcysteine. generation ROS, levels superoxide dismutase (SOD)...
Lung cancer is the leading cause of cancer-related deaths worldwide.