A5101646185- Esophageal and GI Pathology
- Colorectal Cancer Surgical Treatments
- Esophageal Cancer Research and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Abdominal Surgery and Complications
- Acute Kidney Injury Research
- Appendicitis Diagnosis and Management
- Pneumothorax, Barotrauma, Emphysema
- Gastric Cancer Management and Outcomes
- Hernia repair and management
- Enhanced Recovery After Surgery
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Urologic and reproductive health conditions
- Intraperitoneal and Appendiceal Malignancies
- Pneumonia and Respiratory Infections
- Thyroid and Parathyroid Surgery
- Agricultural Practices and Plant Genetics
- Bacterial Infections and Vaccines
- Antiplatelet Therapy and Cardiovascular Diseases
- Amoebic Infections and Treatments
- Vascular Malformations and Hemangiomas
- Bacterial Identification and Susceptibility Testing
- Multiple Myeloma Research and Treatments
- Cancer Diagnosis and Treatment
- Inflammatory mediators and NSAID effects
University of Birmingham
2024
Hayatabad Medical Complex
2023
University of Agriculture Faisalabad
2022-2023
Addenbrooke's Hospital
2020-2023
Peterborough City Hospital
2023
Cambridge University Hospitals NHS Foundation Trust
2020-2022
University of Faisalabad
2022
The University of Texas Rio Grande Valley
2019
Leicester Royal Infirmary
2016
Baylor College of Medicine
2013-2014
Abstract Background High levels of physical activity are associated with reduced risk the blood cancer multiple myeloma (MM). MM is preceded by asymptomatic stages monoclonal gammopathy undetermined significance (MGUS) and smouldering (SMM) which clinically managed watchful waiting. A case study ( N = 1) a former elite athlete aged 44 years previously indicated that multi-modal exercise programme reversed SMM disease activity. To build from this prior study, present pilot firstly examined if...
Abstract Amyand’s hernia, presence of the appendix within an inguinal hernial sac, is a rare condition. We report case 68-year-old woman who presented during COVID-19 pandemic with acute right groin pain due to tender incarcerated hernia. Cross-sectional imaging confirmed She proceeded open appendectomy via canal and primary suture repair her Patient was discharged following day. Surgical management hernia varies depending on resources, clinical findings personal experience. In our opinion...
We evaluated the intensity of antibiotic therapy in patients whom etiology community-acquired pneumonia (CAP) was determined using newly available diagnostic techniques. For 1 year, we studied all admitted for findings consistent with CAP. Sputum and blood cultures, urinary pneumococcal Legionella antigens, viral polymerase chain reaction (PCR) were prospectively. Patients stratified based on final diagnoses: proven bacterial, presumptive viral, fungal, undetermined, uninfected. number...
The aim of the present study was to determine clinical features Aerococcus infections and significance species isolated from any samples.Electronic records all cultures yielding 2002 2012 were obtained three tertiary care hospitals. We performed an in-depth review medical records.Aerococcus ≥ 1 site in 93 patients. Blood positive 64 patients; 15 with definite bacteremia, including 3 endocarditis, 7 urinary tract infections, 13 probable 36 which judged be a possible contaminant. Of 19 urine...
A comprehensive study was conducted to investigate the effect of temperature variations water bath along with sample's storage duration on results glutaraldehyde coagulation test (GCT), being developed for diagnosis tuberculosis.Furthermore, association GCT and tuberculosis, tuberculosis + Hepatitis C virus positive, hepatitis infected control negative humans also assessed.The blood samples from positive as well animals were collected carried variation at which performed (V1-V6).The...
Primary retroperitoneal mucinous cystadenoma (PRMC) is a rare tumour. It was first reported in 1965, and since then, less than 100 cases have been reported. cystic nature most commonly affects the female population. becomes symptomatic later stages due to its mass effect, making diagnosis challenging early asymptomatic stage. We report case of 32-year-old who presented with abdominal pain left iliac fossa. Diagnostic imaging revealed large lesion retroperitoneum. A midline laparotomy...
The poultry industry suffers from various diseases or stresses. In poultry, apart being antipyretic, acetylsalicylic acid (ASA) is widely used to cope with different issues including heat stress, and respiratory digestive orders. This study evaluated the beneficial toxic effects of ASA at dose levels in broiler birds. To evaluate these it necessary examine physical serum biochemical parameters as well histopathological changes tissue sections taken birds under experimental trial. was...
Introduction: ST-segment elevation myocardial infarction (STEMI) is one of the most common heart problems worldwide. So far percutaneous coronary intervention (PCI) has proved to be successful method restore blood flow after a STEMI attack. However, breakdown plaques often results in failed restoration blood. The no-reflow phenomenon complicates treatment and delays patient’s recovery. Statins have helped reduce cholesterol levels thus been used during primary PCI enhance chance reflow....
Abstract Background Superficial surgical site infection is a common morbidity following bowel resection surgery involving stoma formation with clinical and financial implications. The aim of the study was to evaluate role topical skin adhesive, 2-octylcyanoacrylate (2-OCA) in reducing wound infections colorectal surgery. Methods We performed retrospective, single centre, cohort using notes. Patients over age 18, undergoing (elective or emergency) period 5 years from January 2015 December...
Abstract Background Management of Acute appendicitis changed significantly in the UK during COVID-19. The aim study was to compare management before and COVID-19 pandemic. Materials Methods We performed a single centre retrospective cohort comparing acute pandemic from March - August 2019 Pandemic March- 2020. Results Over period 6 months, total 179 patients were diagnosed with versus 152 In 2019, median age 33 52% (n=93) female. 2020, 37 48% (n=73) At first presentation, 97% (174/179)...
Abstract The incidence and prevalence of syphilis are rising worldwide. Rectal is a rare condition with few reported cases in the literature therefore often missed from differential diagnosis atypical anorectal ulceration. We report case 64-year-old male who presented change bowel habit palpable rectal mass on examination. Colonoscopy revealed small, ulcerated lesion rectum. However, histopathological analysis radiological assessments were inconclusive. A cutaneous ulceration prompted repeat...
Abstract Background A leak following oesophago-gastric surgery remains a life-threatening complication associated with long intensive care stay and high mortality morbidity. We hypothesised that Endoluminal Vacuum Therapy (EVT) could be used prophylactically to provide source control, prevent mediastinitis minimise sepsis related morbidity if breakdown of an oesophageal or gastric anastomosis repair occurred. In the first instance, this particularly attractive adjunct in cases where...
Abstract Esophageal leaks present a significant management challenge, especially in patients with delayed presentation and established sepsis. Endoluminal vacuum therapy (EVT) is an emerging treatment strategy which may reduce morbidity mortality compared to traditional treatments this patient group. We report the outcomes for esophageal from range of different causes that were treated EVT tertiary UK hospital over 10-year period. Methods Between April 2011 March 2021, 45 median age 67 years...
Abstract A number of Oesophagogastric (OG) conditions such as Achalasia, Gastroparesis, Oesophageal dysmotility (OD) and Pyloric dysfunction (PD) can be treated with Botulinum Toxin (BTxA). The aim our study was to assess the use costs endotherapy within a tertiary unit. We performed retrospective analysis data collected over 2-year period at unit from November 2015 2017. found 68 eligible patients dysmotility, dysfunction. median treatment sessions were Achalasia 2 (1-3), Gastroparesis:...
Abstract A 67-years-old female presented with right lower abdominal pain and raised inflammatory markers. computed tomography scan showed marked changes collections adjacent to terminal ileum. Patient was managed intravenous antibiotics initially. Subsequent colonoscopy a bulky 8cm caecal pole tumour involving ileocaecal valve. Histopathology confirmed diagnosis of moderately differentiated adenocarcinoma. Staging CT negative for distant metastases. The patient subsequently proceeded...
Abstract Background Endoluminal vacuum therapy (EVT) is an emerging treatment strategy for UGI leaks. When compared to traditional treatments strategies EVT reported reduce morbidity and mortality, especially in patients with delayed presentation established sepsis. We report the outcomes leaks perforations treated using ad-hoc endoluminal device (EVD) a tertiary UK hospital over 10-year period. Methods Sixty-seven from disparate causes were between April 2011 July 2021. The EVD was...
Abstract Background Perforation of the cervical oesophagus is an extremely rare but recognised complication thyroidectomy. As with all oesophageal perforations management depends on timing diagnosis in relation to injury, size wall defect, extent extraluminal contamination, and how unwell patient respect sepsis. We report a case complete transection during total thyroidectomy its subsequent management. Methods A previously well 32-year-old female had neck dissection for papillary carcinoma...
Abstract Background Endoluminal vacuum therapy (EVT) is an emerging treatment strategy for the management of anastomotic leaks following oesophagectomy. However, patients are often critically unwell with mediastinitis and established sepsis by time leak diagnosed. This results in a protracted recovery period regardless effectiveness EVT treating leak. Prophylactic to protect anastomosis oesophagectomy may reduce incidence leak, and/or if does fail. We report outcomes two considered high risk...