A5000098283- Cardiac Ischemia and Reperfusion
- Traditional Chinese Medicine Analysis
- Acute Kidney Injury Research
- Mitochondrial Function and Pathology
- Lipid metabolism and disorders
- Cancer, Hypoxia, and Metabolism
- Blood Pressure and Hypertension Studies
- Cardiovascular Function and Risk Factors
- Nitric Oxide and Endothelin Effects
- Firm Innovation and Growth
- Ovarian function and disorders
- Thyroid Cancer Diagnosis and Treatment
- Corporate Finance and Governance
- Heme Oxygenase-1 and Carbon Monoxide
- Smart Agriculture and AI
- Epigenetics and DNA Methylation
- MicroRNA in disease regulation
- Islamic Finance and Banking Studies
- Energy, Environment, Economic Growth
- Cancer Cells and Metastasis
- Advanced MRI Techniques and Applications
- Salivary Gland Disorders and Functions
- Economic Development and Digital Transformation
- Environmental Sustainability in Business
- Diabetes Management and Education
Shenyang The Fourth Hospital of People
2019-2024
The Fourth People's Hospital
2021-2024
Hunan University of Technology
2022-2024
China Medical University
2024
Shenyang Medical College
2020
X-Fab (Germany)
2019
Polycystic ovary syndrome (PCOS) is a universal endocrine and metabolic disorder prevalent in reproductive aged women. PCOS often accompanied with insulin resistance (IR) which an essential pathological factor. Although there no known cure for PCOS, cangfudaotan (CFDT) decoction widely used the treatment of PCOS; nevertheless, underlying mechanism not clear. In this study, 40 Sprague-Dawley (SD) rats (female) were randomized to 4 groups, namely control group, PCOS+CFDT PCOS+metformin group....
Acute lung injury (ALI), which is induced by renal ischemia-reperfusion (IR), one of the leading causes acute IR-related death. Obesity raises frequency and severity kidney (AKI) ALI. Tanshinone IIA (TIIA) combined with cyclosporine A (CsA) was employed to lessen apoptosis led IR evaluate whether TIIA CsA could alleviate regulating mitochondrial function through PI3K/Akt/Bad pathway in obese rats. Hematoxylin-eosin (HE) staining used assess histology injury. Terminal deoxynucleotidyl...
Abstract Background Acute myocardial injury (AMI), which is induced by renal ischemia-reperfusion (IR), a significant cause of acute kidney (AKI)-related associated death. Obesity increases the severity and frequency AMI AKI. Tanshinone IIA (TIIA) combined with cyclosporine A (CsA) pretreatment was used to alleviate cell apoptosis IR, determine whether TIIA CsA would attenuate modulating mitochondrial function through PI3K/Akt/Bad pathway in obese rats. Methods Male rates were fed high fat...
Abstract Obesity, which has unknown pathogenesis, can increase the frequency and seriousness of acute myocardial infarction (AMI). This study evaluated effect Huayu Qutan Recipe (HQR) pretreatment on apoptosis induced by AMI regulating mitochondrial function via PI3K/Akt/Bad pathway in rats with obesity. For vivo experiments, 60 male were randomly divided into 6 groups: sham group, (obese) 4.5, 9.0 18.0 g/kg/d HQR groups. The models fed different concentrations for 2 weeks before AMI. vitro...
Objective: Obesity enhances the frequency and severity of acute kidney injury (AKI) induced by renal ischemia-reperfusion (IR). Tanshinone IIA (TIIA) pre-treatment was used to alleviate IR, whether TIIA can attenuate cell apoptosis via modulating mitochondrial function through PI3K/Akt/Bad pathway in obese rats examined. Methods: Male rates were fed a high-fat diet for 8 weeks generate obesity, followed 30 min ischemia 24 h reperfusion AKI. The male given (5 mg/kg.d, 10 20 mg/kg.d) 2 before...
As a widely applied traditional Chinese medicine (TCM), Jian-Pi-Yi-Shen (JPYS) decoction maybe in curing premature ovarian failure (POF) besides chronic kidney disease (CKD). In vivo experiments, 40 female SD (8-week-old) rats were randomized into four groups, namely, control group (negative control), POF model group, JPYS treatment and triptorelin (positive control). was treated with (oral, 11 g/kg) for 60 days, the (injection, 1.5 mg/kg) 10 days before administration of cyclophosphamide...
Efficient management of financial resources plays a crucial role in the sustainable growth enterprises. We use Python software crawler, word segmentation, and counting functions to count relevant frequencies. Furthermore, we apply text analysis measure level enterprises’ digital transformation. Combined with data from listed companies China, conduct an in-depth study on impact enterprises' transformation misallocation resources. The findings suggest enterprise can reduce resource mismatches....
Proinflammatory factor tumor necrosis factor-α (TNF-α) is an important inflammatory mediators in microenvironment and autoimmune diseases, it highly expressed many solid tumors microenvironment, showing a promoting role.However, the molecular mechanisms underlying TNF-α-increased invasion of thyroid cancer are still not fully understood.In order to explore whether TNF-α plays key role process epithelial mesenchymal transition (EMT) papillary carcinoma (PTC), we used induce EMT different PTC...
China has the largest population of individuals with diabetes, and prevalence various complications among patients type 2 diabetes remains high. Diabetic nephropathy affects approximately 20% to 40% diabetic patients, becoming a major cause chronic kidney disease end-stage renal disease. Furthermore, around 50% develop peripheral neuropathy (DPN), which is closely associated physical disability, increased healthcare costs, reduced work productivity. There an urgent need for novel strategies...
Abstract Objective: The primary aim of this study is to examine the hemodynamics retrobulbar and intrarenal in changes early stage type 2 diabetes mellitus (T2DM) patients from 2000 2015 assess incidence associated with diabetic kidney disease (DKD) retinopathy (DR). Method: Our contained 60 subjects newly diagnosed T2DM were divided into groups base on mean resistive index (RI) (≤0.7 >0.7) hemodynamic compare between-group differences also conclude incidences (DR)subsequently a long...
The main objectives of this study were to assess the early changes in pulmonary function and intrarenal haemodynamics determine correlation between patients with type 2 diabetes mellitus (T2DM).96 T2DM (diabetes group) without kidney disease (DKD) 33 healthy subjects (control enrolled studies intended associated diabetes, as well haemodynamics.Pulmonary functional parameters negatively correlated HbA1c levels duration (P< 0.05). Moreover, renal positively (P<0.05). Additionally, Multiple...
Since December 2019, the outbreak of coronavirus disease 2019 (COVID-19) has occurred in China. Higher risk COVID-19 infection and worse prognosis were observed among patients with diabetes. There are rigorous challenges existing terms diabetes prevention glycemic control primary medical care during period COVID-19. Here, expert recommendations presented by Chinese diabetologists, healthcare providers, public health administrators to improve ability facilities provide standardized basic...
<title>Abstract</title> In the context of promoting resource conservation and environmentally friendly societal development worldwide, this study introduces theoretical framework green credit reputation into analysis bank risk assumption. An evolutionary game model is constructed to simulate process commercial banks implementing derive final equilibrium result. By utilizing annual data from Chinese for years 2010-2021, policy (GCP) treated as a quasi-natural experiment, multiple time period...
Abstract Background: Acute myocardial injury (AMI), which is induced by renal ischemia-reperfusion (IR), a significant cause of acute kidney (AKI)-related associated death. Obesity increases the severity and frequency AMI AKI. Tanshinone IIA (TIIA) combined with cyclosporine A (CsA) pretreatment was used to alleviate cell apoptosis IR, determine whether TIIA CsA would attenuate modulating mitochondrial function through PI3K/Akt/Bad pathway in obese rats. Methods: Male rates were fed high fat...
Abstract Background: Acute myocardial injury (AMI), which is induced by renal ischemia-reperfusion (IR), a significant cause of acute kidney (AKI)-related associated death. Obesity increases the severity and frequency AMI AKI. Tanshinone IIA (TIIA) combined with cyclosporine A (CsA) pretreatment was used to alleviate cell apoptosis IR, determine whether TIIA CsA would attenuate modulating mitochondrial function through PI3K/Akt/Bad pathway in obese rats. Methods: Male rates were fed high fat...