Histopathological interpretation of proliferative nodules occurring in association with congenital melanocytic nevi can be very challenging due to their similarities malignant melanoma and arising nevi. We hereby report a diagnostically case nevus ulcerations, which was originally misdiagnosed as melanoma. Subsequent histopathological examination consultation by one the authors (R.L.) mass spectrometry imaging analysis rendered diagnosis nodules. In this case, imaging, novel method capable...

Our objective is to report on the efficacy and safety of dermal fat graft in augmentation phalloplasty performed patients who presented complaining "small penis," evaluate cosmetic psychological outcomes it.From April 2010 January 2015, 23 Chinese adult aged 18 33 years (average, years) with subjective perception small penis were included; all requested an increase penile dimension underwent elongation (suprapubic skin advancement-ligamentolysis) girth enhancement by graft. Besides...

Objective Post-burn cicatricle contractures of neck pose a challenge for plastic and reconstructive surgeons. To improve functional cosmetic results, to minimize the donor-site morbidity, we use pre-expanded cervico-acromial fasciocutaneous flap based on supraclavicular artery as feasible choice resurfacing large skin defects neck. Methods In this series, from 2008 2012, 18 patients with ages ranging between 11 42 years (20 flaps 2 in bilateral fashion) suffering post-burn scar were treated....

The most commonly used experimental model for preclinical studies on peripheral nerve regeneration is the sciatic injury model. However, no study has been conducted to evaluate acute modes at same time.We transverse injury, clamp keep epineurium and axon cutting chemical damage in rats degree of four different self-repair after injury.The model, were constructed. Then, function was assessed using clinical evaluation methods electrophysiological examinations, as well immunofluorescence axonal...

Objectives: To report the outcomes of two‐stage repair for adult hypospadias using a buccal mucosa graft as tube. Methods: A total 57 patients who underwent surgery severe urethral defect at our institution from January 2002 to March 2010 were included in this analysis. The urethroplasty procedure penile urethra reconstruction with used tube first stage, anastomosis unobstructed second stage and scrotal fascio‐cutaneous flap transferred resurface reconstructed waterproofing. Results: No...

We review our experience in urethrocutaneous fistula (UCF) repair after hypospadias surgery to investigate the risk factors for unsuccessful outcome.Two hundred eleven patients had undergone UCF department from January 2005 December 2015. This study included 185 who were followed up more than 6 months. The age of patients, size, site and number UCFs, repairs, urethral complications other UCF, postoperative infection as potential factors. Binary logistic regression analysis was used...

To investigate the influence of immunization routes onIgG, IgA and IgM production in systemic mucosal compartments, we immunized mice with keyhole limpet hemocyanin (KLH) via oral, intranasal (i.n.) or subcutaneous (s.c.) alone combined intravenous (i.v.) route. We found that administering antigen intravenously could affect antibody formation secreting cells (ASCs) depending on route previously used. Combined oral/i.v. but not s.c./i.v. caused a great increase ASCs spleen enhanced small...

Background Flap prefabrication is to turn a random flap into an axial by transferring vascular pedicle. Methods In the past 13 years, we have prefabricated 20 flaps in patients superficial temporal artery and its concomitant veins. Typically, 50- 800-mL tissue expander was implanted donor site. After maturation, raised transferred locally cover large defect on face. All cases were followed up regularly. Results The patients' age between 3 27 size of 3.5 × 5.5 cm2 15 cm2, length 10 cm....

Abstract Over the past 20 years, we have designed various types of expanded cervical flaps for large facial defects and achieved excellent tissue matching. This study was performed to propose a treatment strategy flap selection reconstruction different units. The authors retrospectively reviewed application rehabilitation in our department between January 2003 2023. included 122 patients with unilateral (62.3%) bilateral (37.7%) deformities ranging from zygomatic arch chin. median area...

In patients with facial paralysis, the free functional gracilis muscle transfer is preferred for reanimation. The choice of an adequate motor nerve to innervate transplanted one procedure's key components. We present a comparative study between cross-facial graft (CFNG) and masseteric as donor nerves reinnervated flap in complete paralysis. Retrospective analysis was performed on all paralysis who had reanimation January 2014 December 2021. Only those received by either CFNG or were included...

Extensive scarring and giant nevi on the mid lower faces places further demands scar resurfacing in terms of match, size, thickness. The area supraclavicular cervical flap is rather limited, but expansion could expand its utility facial resurfacing.Rectangular expanders were inserted via incisions at upper fringes clavicles, implanted under areas. After full expansion, based artery was elevated to cover defects left by surgical removal or tumor. Pedicle division performed 10 14 days...

Port wine stain (PWS) is a congenital benign vascular malformation. Laser treatment the main therapy for PWS. But some patients are not sensitive to it, and failed laser will leave scars on face. Hence in this study, authors used prefabricated flap carried by superficial temporal artery treat PWS.Nine diagnosed with large-scaled PWS (occupying more than half of cheek) from January 2008 December 2017 were selected study. One them did finish treatment. Eight completed all scheduled treatments....

CD89 (FcαRI), the receptor of IgA, can shed from cells to form complexes with IgA in serum and is supposed participate pathogenesis nephropathy (IgAN). There are contradictory results on their utility clinical practice. This study aimed at investigating whether sCD89-IgA help diagnosis or evaluation disease. A sandwich ELISA was established using anti-CD89 as a capture antibody HRP-conjugated anti-IgA detection antibody. method used measure levels IgAN patients without immunosuppressant...

Resurfacing large facial defect is a continuing challenge for plastic surgeons. Skin graft or free flap hard to obtain satisfactory results beyond the skill of most The authors performed 13 expended submental island flaps resurface middle and lower defects achieved results. In first stage operation, implanted one soft tissue expander in anterior neck region which was expanded over an average 3 months. second elevated defect. For patients who request aesthetic allow 2-stage our method...

Abstract Backgrounds Giant neurofibromas occurring in individuals diagnosed with neurofibromatosis type 1 (NF1) often result considerable disfigurement, functional impairment, and diminished quality of life. Although debulking surgery poses inherent risks complications, it remains the most efficacious approach to address these issues. The primary objective this study was share our surgical experience giant extremities trunk wall NF1 patients which may help surgeons minimize intraoperative...