A5101717096- Lung Cancer Diagnosis and Treatment
- Urological Disorders and Treatments
- COVID-19 diagnosis using AI
- Radiomics and Machine Learning in Medical Imaging
- Ovarian cancer diagnosis and treatment
- Liver Disease Diagnosis and Treatment
- Urologic and reproductive health conditions
- Nanoplatforms for cancer theranostics
- Hepatocellular Carcinoma Treatment and Prognosis
- Genital Health and Disease
- Endometriosis Research and Treatment
- Gastric Cancer Management and Outcomes
- Cancer Research and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Cardiac Valve Diseases and Treatments
- Cancer, Hypoxia, and Metabolism
- Growth Hormone and Insulin-like Growth Factors
- Reproductive System and Pregnancy
- Pancreatic and Hepatic Oncology Research
- Gestational Trophoblastic Disease Studies
- Vitamin D Research Studies
- Pancreatitis Pathology and Treatment
- Metabolism, Diabetes, and Cancer
- Colorectal Cancer Treatments and Studies
- Pleural and Pulmonary Diseases
Chinese Academy of Medical Sciences & Peking Union Medical College
2015-2025
Xiyuan Hospital
2021-2025
Peking University
2024-2025
Peking University Third Hospital
2024-2025
Guangxi University of Chinese Medicine
2024
Guangxi University
2024
Obstetrics and Gynecology Hospital of Fudan University
2018-2023
Mianyang Central Hospital
2008-2023
University of Electronic Science and Technology of China
2021-2023
Fudan University
2023
To evaluate the association between dietary inflammatory index (DII) and Atherosclerotic cardiovascular disease (ASCVD) among U.S. adults.We collected data from National Health Nutrition Examination Survey (NHANES) 1999 2018. Adults who reported complete information to diagnose ASCVD calculate DII were included. We used three models differentially adjust covariates, including age, sex, race or ethnicity, education level, smoking status, poverty, insurance, body mass index, hyperlipemia,...
To explore the morbidity and risk factors of postoperative pancreatic fistula (POPF) following pancreaticoduodenectomy.The data from 196 consecutive patients who underwent pancreaticoduodenectomy, performed by different surgeons, in General Hospital People's Liberation Army between January 1(st), 2013 December 31(st), were retrospectively collected for analysis. The diagnoses POPF clinically relevant (CR)-POPF pancreaticoduodenectomy judged strictly International Study Group on Pancreatic...
Intraoperative diagnosis of metastatic tumors is significant importance to the treatment ovarian cancer. NIR-II fluorescence imaging holds great promise for facile detection tumor in situ with high sensitivity and resolution. Herein, a kind fluorescent polymer dots (NIR-II Pdots) brightness developed real-time cancer via imaging. The Pdots are constructed self-assembly emissive aggregation induced emission luminogens AIEgens) poly (styrene)-graft-poly(ethylene glycol) water. Such show very...
Abstract Background Pneumothorax (PTX) may cause a life-threatening medical emergency with cardio-respiratory collapse that requires immediate intervention and rapid treatment. The screening diagnosis of pneumothorax usually rely on chest radiographs. However, the pneumothoraces in X-rays be very subtle highly variable shape overlapped ribs or clavicles, which are often difficult to identify. Our objective was create large X-ray dataset for pixel-level annotation train an automatic...
The high mortality rate of ovarian cancer can be primarily attributed to late diagnosis and early lymph node (LN) metastasis. anatomically deep-located ovaries own intricate anatomical structures lymphatic drainages that compromise the resolution sensitivity near-infrared first-window (NIR-I) fluorescence imaging. Reported NIR-II imaging studies focused on late-stage metastasis detection via intraperitoneal xenograft model. However, given significant improvement in patient survival...
Abstract Background Most cancers favor glycolytic-based glucose metabolism. Hexokinase-2 (HK2), the first glycolytic rate-limiting enzyme, shows limited expression in normal adult tissues but is overexpressed many tumor tissues, including ovarian cancer. HK2 has been shown to be correlated with progression and chemoresistance of cancer could a therapeutic target. However, systemic toxicity inhibitors their clinical use. Since follicle-stimulating hormone (FSH) receptor (FSHR) not nonovarian...
Abstract Background Cardiovascular disease (CVD) is the leading cause of mortality, and vascular calcification has been highly correlated with CVD events. Abdominal aortic (AAC) shown to predict subclinical incident However, relationship between vitamin C abdominal remains unclear. Objective To investigate dietary AAC among adult population in US. Methods The National Health Nutrition Examination Survey (NHANES) 2013–2014 provided data for cross-sectional study. 2297 subjects (1089 males)...
Abstract Objectives The associations between the triglyceride–glucose (TyG) index with subsequent stroke in American adults are unknown. aim of this study was to determine baseline and trajectories TyG adults. Methods A total 10,132 participants free a history at were included. We quantified association incident stroke, ischemic intracerebral hemorrhage using Cox regression, restricted cubic splines logistic regression analysis. Results There 909 cases over median follow-up 26.6 years. After...
This study aims to explore the morbidity and risk factors of delayed gastric emptying (DGE) following pancreaticoduodenectomy.Between 1 January 2013 31 December 2013, data from 196 consecutive patients who underwent pancreaticoduodenectomy in Chinese PLA General Hospital were recorded retrospectively. A total 17 examined with univariate analysis, multivariate logistic regression analysis was used estimate relative risks.DGE occurred 71 (36.2%). The incidence rates grade A, B C DGE 22.4%...
Early detection of the pulmonary nodule is critical to increase five-year survival rate lung cancer. Many computer-aided diagnosis (CAD) systems have been proposed for assist radiologists in diagnosis. Along this direction, paper proposes a novel automated model using modified V-Nets and high-level descriptor based support vector machine (SVM) classifier. The former candidate latter false positive (FP) reduction. A hard mining scheme retraining devised improve FP reduction performance. SVM...
Chronic stress is suspected to be a causal factor of female subfertility; however, the underlying mechanisms remain unclear. Here, we found that chronic inhibited cyclic adenosine 3′,5′-monophosphate (cAMP) signaling pathway, leading ovarian reserve decline in mice. A model was constructed using restraint for 8 weeks. An elongated estrous cycle and significant increase number atretic follicles were observed group. We identified meiotic arrest failure (MAF) oocytes group, characterized by...
Our objective is to report on the efficacy and safety of dermal fat graft in augmentation phalloplasty performed patients who presented complaining "small penis," evaluate cosmetic psychological outcomes it.From April 2010 January 2015, 23 Chinese adult aged 18 33 years (average, years) with subjective perception small penis were included; all requested an increase penile dimension underwent elongation (suprapubic skin advancement-ligamentolysis) girth enhancement by graft. Besides...
In order to study the characteristics of fire smoke spread and temperature distribution a large indoor pedestrian street under different heat release rates exhaust modes, this paper focuses on analysis spread, visibility, variation curves in an atrium. This uses numerical simulation method conduct research. PyroSim software is used calculate project, which based full-scale experimental design scheme. The results show that conditions higher rate, rate greater than lower rate. Furthermore,...
Background: Peritoneal dissemination is common in advanced ovarian cancer. The completeness of cytoreduction an independent prognostic factor. intraoperative fluorescence imaging via tumor-specific near-infrared fluorophore might improve staging and surgical completeness. A promising target for cancer the gonadotropin-releasing hormone receptor (GnRHR). This study aimed to develop a GnRHR-targeted probe detection peritoneal metastases Methods: Indocyanine green (ICG) was conjugated with GnRH...
Late detection, peritoneal dissemination, chemoresistance and weak response to targeted therapeutics lead high mortality in ovarian cancer. More efficient specific tumor imaging therapeutic agents are needed improve the resection rate of surgery eliminate residual disease. The expression patterns follicle-stimulating hormone (FSH) receptor make it a suitable target for Here, we report strategy develop an organic near-infrared probe FSH receptor-targeted photothermal therapy. FSH-Rh760 was...
Automatic pneumothorax segmentation on chest X-ray images is very crucial for diagnosis and treatment as large could be fatal. The challenging, some small pneumothoraces can subtle, may overlap with the ribs clavicles. Meanwhile, shape variation of also large, which makes more difficult. In this paper, we propose a novel automated framework consists three modules: 1) fully convolutional DenseNet (FC-DenseNet), 2) spatial channel squeeze excitation module (scSE), 3) multi-scale module. order...
Background: Gut microbiota can interact with the central nervous system through gut-brain axis, thus affecting host's chronic stress level, such as anxiety and depression. Current researches show that patients endometriosis often have a high level of stress, which will in turn aggravate by activating β-adrenergic signaling pathway. Therefore, we wondered whether gut associates patients, may provide new insights on how to improve treatment. Methods: We grouped into group control...