A5112529700- Natural product bioactivities and synthesis
- Analytical Chemistry and Chromatography
- Chromatography in Natural Products
- Phytochemistry and Biological Activities
- Traditional Chinese Medicine Analysis
- Phytochemicals and Antioxidant Activities
- Traditional and Medicinal Uses of Annonaceae
- Pharmacological Effects of Natural Compounds
- Soil Carbon and Nitrogen Dynamics
- Phytochemical compounds biological activities
- Fungal Biology and Applications
- Pasture and Agricultural Systems
- Berberine and alkaloids research
- Plant Ecology and Soil Science
- Phytochemistry and Bioactivity Studies
- Microbial Community Ecology and Physiology
- Alkaloids: synthesis and pharmacology
- Phytoestrogen effects and research
- Microbial Natural Products and Biosynthesis
- Genomics and Phylogenetic Studies
- Microfluidic and Capillary Electrophoresis Applications
- Thermal and Kinetic Analysis
- Liver Disease Diagnosis and Treatment
- Ecology and Vegetation Dynamics Studies
- Molecular Sensors and Ion Detection
Shenzhen Institutes of Advanced Technology
2025
Chinese Academy of Sciences
2016-2025
Northeast Institute of Geography and Agroecology
2025
University of Chinese Academy of Sciences
2025
Northwest Institute of Plateau Biology
2005-2024
Qinghai Tibetan Hospital
2017-2024
Shandong University
2024
Institute of Tibetan Plateau Research
2013-2022
Xinjiang Institute of Ecology and Geography
2008-2020
Qinghai University for Nationalities
2019-2020
Understanding the molecular and metabolic interplay between Meloidogyne incognita soybean (Glycine max) root exudates is essential for unraveling plant-nematode interactions. This study investigates transcriptomic responses of M. during pre-parasitic stage metabolomic changes in influenced by nematode activity. Transcriptomic analysis identified 846 differentially expressed genes nematodes exposed to (S-Mi) compared alone (Mi). Upregulated genes, including those encoding sensory receptors...
Deep eutectic solvents (DESs) have attracted significant attention as a promising green media. In this work, twenty-five kinds of benign choline chloride-based DESs with microwave-assisted methods were applied to quickly extract active components from Radix Salviae miltiorrhizae. The extraction factors, including temperature, time, power microwave, and solid/liquid ratio, investigated systematically by response surface methodology. hydrophilic hydrophobic ingredients extracted simultaneously...
Subcritical fluid extraction (SFE) technology was used to extract oil from Nitraria tangutorum seed. The best possible combination of parameters found using response surface methodology (RSM) in a three-variable, three-level Box-Behnken experimental design (BBD). optimum were an time 40 min, pressure 0.60 MPa, temperature 44 °C and raw material particle size 0.45 mm. Conventional solvent supercritical CO2 comparatively used. yield seed obtained SFE 12.92%, which similar or higher than the...
For the first time to our knowledge, we report here methane emissions by plant communities in alpine ecosystems Qinghai–Tibet Plateau. This has been achieved through long-term field observations from June 2003 July 2006 using a closed chamber technique. Strong emission at rate of 26.2±1.2 and 7.8±1.1 μg CH 4 m −2 h −1 was observed for grass community Kobresia humilis meadow Potentilla fruticosa meadow, respectively. A shrub consumed atmospheric 5.8±1.3 on regional basis; plants meadows...
Two-component systems (TCSs) sensing and responding to various stimuli outside inside cells are valuable resources for developing biosensors with synthetic biology applications. However, the use of TCS-based suffers from a limited effector spectrum, hypersensitivity, low dynamic range, unwanted signal crosstalk. Here, we developed tailor-made Escherichia coli whole-cell γ-aminobutyric acid (GABA) biosensor by engineering chimeric GABA chemoreceptor PctC TCS. By testing different TCSs,...
Dracocephalum heterophyllum was a traditional Tibetan medicine possesses various pharmacological effects involved in anti-inflammatory, antibacterial activities. However, its anti-hepatitis, antioxidant activity and bioactive compounds have not been reported, the objective of this research work to investigate D. extracts.
A novel actinomycete strain, designated YIM 002 T , was isolated from a desert soil sample in Gansu Province, north-west China. This isolate formed well-differentiated aerial and substrate mycelia. In the early stages of growth, mycelia fragmented into short or elongated rods. Chemotaxonomically, it contained ll -2,6-diaminopimelic acid cell wall. The cell-wall sugars ribose glucose. Phospholipids present were phosphatidylinositol mannosides, diphosphatidylglycerol. MK-9(H 4 ) predominant...
Traditional Tibetan medicine is important for discovery of drug precursors. However, knowledge the chemical composition traditional medicines very limited due to lack appropriate chromatographic purification methods. In present work, Salvia prattii was taken as an example, and off-line hydrophilic interaction liquid chromatography/reversed-phase chromatography preparative method developed phenylpropanoids with high purity from a crude sample prattii. Based on separation results four...
In this study, a 100 g sample of Saxifraga atrata was processed to separate 1.3 11-O-(4′-O-methylgalloyl)-bergenin (Fr1) after 1 cycle MCI GEL® CHP20P medium pressure liquid chromatography using methanol/water. Subsequently, COX-2 affinity ultrafiltration coupled with reversed-phase successfully used screen for potential ligands in target fraction (Fr1). After 20 runs, 74.1 mg >99% pure (Fr11) obtained. addition, the anti-inflammatory activity further validated through molecular docking...
An offline preparative two-dimensional reversed-phase liquid chromatography/hydrophilic interaction chromatography coupled with hydrophilic solid-phase extraction method was developed for the isolation of flavonoid glycosides from a crude sample Sphaerophysa salsula. First, non-flavonoids were removed using an XAmide cartridge. Based on separation results three different chromatographic stationary phases, first-dimensional preparation performed XAqua C18 prep column, and 15 fractions...
The separation of high-purity compounds from traditional Tibetan medicines plays an important role in investigating their bioactivity. Nevertheless, it is often quite difficult to isolate with high purity because the complexity medicines. In this work, offline two-dimensional reversed-phase preparative method was successfully developed for Oxytropis falcata. Based on analysis results, ODS C18 prep column used first-dimensional preparation, and 14.8 g crude sample separated into five...