A5004434989- Prostate Cancer Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Renal cell carcinoma treatment
- Sexual function and dysfunction studies
- Inflammatory Biomarkers in Disease Prognosis
- Renal and related cancers
- Urologic and reproductive health conditions
- Prostate Cancer Treatment and Research
- Nutrition and Health in Aging
- Sexuality, Behavior, and Technology
- Urinary Bladder and Prostate Research
- Urinary and Genital Oncology Studies
- Radiomics and Machine Learning in Medical Imaging
- Frailty in Older Adults
- Genital Health and Disease
- Urological Disorders and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Sexual Differentiation and Disorders
- MRI in cancer diagnosis
- Nutritional Studies and Diet
- MicroRNA in disease regulation
- Pediatric Urology and Nephrology Studies
- Abdominal vascular conditions and treatments
- Marriage and Sexual Relationships
- Chronic Kidney Disease and Diabetes
University of Trieste
2021-2025
Ospedale di Cattinara
2021-2024
Azienda Ospedaliero-Universitaria Careggi
2023
University of Florence
2023
University of Pisa
2023
Western Regional Hospital
2023
Sapienza University of Rome
2023
Jouf University
2021
Background: This study aims to evaluate the safety and efficacy of prostatic artery embolization (PAE) in elderly, multimorbid patients with benign hyperplasia (BPH). Additionally, it seeks identify technical clinical factors that predict failure at mid-term follow-up. Methods: We analyzed records 175 consecutive who underwent PAE. Technical success was defined as achieving on least one side. Safety assessed using Clavien-Dindo classification. The pre-procedural international prostate...
Background and Objectives: We aimed at evaluating the impact of Controlling Nutritional Status (CONUT) score on clinically significant decline in estimated glomerular filtration rate (eGFR) patients with non-metastatic Clear Cell Renal Carcinoma (ccRCC) undergoing radical nephrectomy (RN). Materials methods: retrospectively analyzed a multi-institutional cohort 140 ccRCC who underwent RN between 2016 2018 three Urological Centers. The CONUT was calculated an algorithm including serum...
In the last years incidence of renal neoplasms has been steadily increasing, along with average age patients at time diagnosis. Surgical management for localized disease is becoming more challenging because patients’ frailty. We conducted a multi-center prospective study to evaluate role G8 as screening tool in assessment intra and post-operative complications elderly (≥70 y.o.) undergoing surgery kidney cancer. A total 162 were prospectively enrolled between January 2015 2019 divided into...
Background and Objectives: To assess efficacy safety of Percutaneous Cryoablation (PCA) small renal masses (SRMs) using Trifecta outcomes in a large cohort patients who were not eligible for surgery. Materials methods: All PCAs performed four different centers between September 2009 2019 retrospectively evaluated. Patients divided two groups depending on dimensional criteria: Group-A: diameter ≤ 25 mm Group-B: > mm. Complications rates reported classified according to the Clavien–Dindo...
The primary aim of this study was to evaluate if exposure 5-alpha-reductase inhibitors (5-ARIs) modifies the effect MRI for diagnosis clinically significant Prostate Cancer (csPCa) (ISUP Gleason grade ≥ 2).This is a multicenter cohort including patients undergoing prostate biopsy and at 24 institutions between 2013 2022. Multivariable analysis predicting csPCa with an interaction term 5-ARIs PIRADS score performed. Sensitivity, specificity, negative (NPV) positive (PPV) predictive values...
Background and Objectives: To date, sparse evidence exists about the impact of inflammatory serum markers in predicting perioperative complications after radical cystectomy (RC) for bladder cancer (BC). Here, we evaluated role neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), lymphocyte-to-monocyte (LMR), systemic immune-inflammation index (SII), C-reactive protein (CRP), plasma fibrinogen morbidity unplanned 30-days readmission RC BC. Materials methods: We relied on a...
The impact of warm ischemia time (WIT) on renal functional recovery remains controversial. We examined the length WIT>30 min long-term function following on-clamp partial nephrectomy (PN).Data from 23 centers for patients undergoing PN between 2000 and 2018 were analyzed. included with two kidneys, single tumor, cT1, minimum 1-year follow-up, preoperative eGFR≥60 mL/min/1.73m2. Patients divided into groups according to WIT length: group I "WIT≤30 min" II "WIT>30 min." A propensity-score...
To externally validate Yonsei nomogram. From 2000 through 2018, 3526 consecutive patients underwent on-clamp PN for cT1 renal masses at 23 centers were included. All had two kidneys, preoperative eGFR ≥60 ml/min/1.73 m2, and a minimum follow-up of 12 months. New-onset CKD was defined as upgrading from stage I or II into ≥III. We obtained the CKD-free progression probabilities 1, 3, 5, 10 years all by applying nomogram found https://eservices.ksmc.med.sa/ckd/. Thereafter, external validation...
OBJECTIVES: The molecular mechanisms of muscle invasion in bladder cancer (BC) are still unknown.Based on the microRNA (miRNA) signature BC by deep sequencing, we recently found that several double-stranded mature miRNAs derived from same pre-miRNAs acted as tumor suppressors regulating common target genes.In this study, focused miR-199 family members (miR-199a-3p/-5p and miR-199b-3p/-5p) were downregulated signature.The aim study was to investigate functional role identify targets...
Fournier's Gangrene (FG) has still a mortality rate up to 45%. Several studies identified prognostic factors but there is knowledge gap concerning procalcitonin (PCT) levels and risk in FG. This study aimed assess the role of PCT as factor FG.The medical records 20 male FG patients admitted at Department Urology "Cattinara" Hospital, University Trieste between January 2019 November 2020 were retrospectively reviewed. Clinical, demographic, microbiological data collected. The Severity Index...
Abstract Background/objectives: Peyronie's disease (PD) is a connective tissue disorder characterized by the formation of fibrous plaques in tunica albuginea penis, resulting pain, deformity, and erectile dysfunction. The Disease Questionnaire (PDQ) assesses severity symptoms, including penile curvature, dysfunction, as well impact on sexual function, emotional well-being, overall quality life. Previous studies validated PDQ US version confirmed its test–retest reliability responsiveness....
Fluorescence confocal microscopy (FCM) represents a novel diagnostic technique able to provide real-time histological images from non-fixed specimens. As consequence of its recent developments, FCM is gaining growing popularity in urological practice. Nevertheless, evidence still sparse, and, at the moment, applications are heterogeneous. We performed narrative review current literature on this topic. Papers were selected Pubmed, Embase, and Medline archives. focused prostate cancer (PCa),...