A5048526055- Smoking Behavior and Cessation
- Obesity, Physical Activity, Diet
- Behavioral Health and Interventions
- Substance Abuse Treatment and Outcomes
- Nicotinic Acetylcholine Receptors Study
- Gambling Behavior and Treatments
- Neurotransmitter Receptor Influence on Behavior
- Cannabis and Cannabinoid Research
- Impact of Technology on Adolescents
- Sexuality, Behavior, and Technology
- Biochemical Analysis and Sensing Techniques
- Alcohol Consumption and Health Effects
- Child and Adolescent Psychosocial and Emotional Development
- Homelessness and Social Issues
- Air Quality and Health Impacts
- School Health and Nursing Education
- Olfactory and Sensory Function Studies
- Eating Disorders and Behaviors
- Consumer Attitudes and Food Labeling
- Nutrition, Health and Food Behavior
- Noise Effects and Management
- Prenatal Substance Exposure Effects
- Mental Health Research Topics
- Receptor Mechanisms and Signaling
- Child Development and Digital Technology
Yale University
2016-2025
Connecticut Mental Health Center
2012-2023
Johns Hopkins University
2022
Virginia Commonwealth University
2022
Vanderbilt University
2018
VA Connecticut Healthcare System
2001-2017
Behavioral Health Services
2017
Yale New Haven Hospital
2017
Institute for Community Living
2017
Hartford Financial Services (United States)
2017
Journal Article Reasons for Electronic Cigarette Experimentation and Discontinuation Among Adolescents Young Adults Get access Grace Kong, PhD, PhD 1Department of Psychiatry, Yale University School Medicine, New Haven, CT; Search other works by this author on: Oxford Academic PubMed Google Scholar Meghan E. Morean, Dana A. Cavallo, Deepa R. Camenga, MD, MD 2Department Pediatrics, CT Suchitra Krishnan-Sarin, Nicotine & Tobacco Research, Volume 17, Issue 7, July 2015, Pages 847–854,...
An inability to maintain abstinence is a key indicator of tobacco dependence. Unfortunately, little evidence exists regarding the ability major dependence measures predict smoking cessation outcome. This paper used data from four placebo-controlled trials and one international epidemiological study determine relations between success Fagerström Test for Nicotine Dependence (FTND), Heaviness Smoking Index, Syndrome Scale, Wisconsin Inventory Motives. Results showed that much predictive...
Video game playing may negatively impact youth. However, the existing literature on gaming is inconsistent and often has focused aggression rather than health correlates of prevalence problematic gaming.We anonymously surveyed 4028 adolescents about reported problems with other behaviors. A total 51.2% sample (76.3% boys 29.2% girls).There were no negative in lower odds smoking regularly; however, girls who less likely to report depression more getting into serious fights carrying a weapon...
Electronic cigarette (e-cigarette) use is increasing rapidly among high school (HS) students. Of concern, e-cigarettes can be used to vaporize cannabis, although rates adolescents are unknown. We evaluated lifetime of using cannabis all e-cigarette users (27.9%), (29.2%), and both (18.8%); common means vaporizing including hash oil, wax infused with Δ-9-tetrahydrocannabinol (THC), dried cannabis; demographic predictors cannabis.In the spring 2014, 3847 Connecticut HS students completed an...
There is limited evidence on electronic cigarette (e-cigarette) use among U.S. adolescents.Cross-sectional, anonymous surveys conducted in 4 high schools (HS; n = 3,614) and 2 middle (MS; 1,166) Connecticut November 2013 examined e-cigarette awareness, patterns, susceptibility to future use, preferences, product components used (battery type, nicotine content, flavors), sources of marketing access.High rates awareness (MS: 84.3%; HS: 92.0%) lifetime (3.5% MS, 25.2 % HS) current (1.5% 12%...
Electronic cigarette (e-cigarette) use is common among youth, and there are concerns that e-cigarette leads to future conventional use. We examined longitudinal associations between past-month characterize the stability directionality of these tobacco trajectories over time.High school students (N = 808, 53% female) completed surveys across 3 waves (2013, 2014, 2015) in public schools Connecticut. Using autoregressive cross-lagged models, we bidirectional relationships time. Models were...
<h3>Background</h3> Cigarette smoking rates in schizophrenia are higher than the general population. <h3>Objectives</h3> To determine whether cigarette modifies cognitive deficits and to establish role of nicotinic acetylcholine receptors (nAChRs) mediating smoking–related enhancement. <h3>Design</h3> Neuropsychological assessments were performed at baseline, after overnight abstinence, reinstatement across 3 separate test weeks during which subjects pretreated a counterbalanced manner with...
Abstract Nicotine and other constituents of tobacco smoke elevate dopamine (DA) serotonin (5‐HT) levels in brain may cause homeostatic adaptations DA 5‐HT transporters. Since sex steroids alter transporter expression, the effects smoking on availability differ between sexes. In present study, availabilities were quantitated using single photon emission computed tomography (SPECT) imaging approximately 22 h after bolus administration [ 123 I]β‐CIT, an analog cocaine which labels Forty‐two...
Nicotine, the addictive chemical in tobacco smoke, initiates its actions brain through nicotinic acetylcholine receptors (nAChRs). In particular, nAChRs containing beta2-subunits (beta2*-nAChRs) most prevalent subtype, mediate reinforcing properties of nicotine. We hypothesized that abnormal numbers beta2*-nAChRs during early abstinence contribute to perpetuation addiction smoking. Using molecular imaging, specifically single-photon emission computed tomography with nAChR agonist radiotracer...
This article presents the proceedings of a symposium held at meeting International Society for Biomedical Research on Alcoholism (ISBRA) in Mannheim, Germany, October 2004. explored potential role hypothalamic-pituitary-adrenal (HPA) axis dysregulation upon relapse. HPA stimulation induces release glucocorticoid cortisol, compound with profound effects behavior and emotion. Altered stress-responses abstinent alcohol-dependent subjects, therefore, may influence their affective behavioral...
This study aims to explore the prevalence and health correlates of problematic Internet use among high school students in United States.A cross-sectional survey with a sample size 3,560 was conducted schools Connecticut. Demographic data, characteristics use, measures, risk behaviors were assessed. Chi-square logistic regression analyses used relationship between as well related gender differences.When diagnosed criteria modeled after Minnesota Impulsive Disorder Inventory that address core...
Self-reported impulsivity confers risk factor for substance abuse. However, the psychometric properties of many self-report measures have been questioned, thereby undermining interpretability study findings using these measures. To better understand measurement limitations and to suggest a path assessing self-reported with greater stability, we conducted comprehensive evaluation Barratt Impulsiveness Scale-11 (BIS-11), Behavioral Inhibition Activation Scales (BIS/BAS), Brief Self-Control...
Available levels of nicotinic acetylcholine receptors containing the beta(2) subunit (beta(2)*-nAChR) are higher in recently abstinent tobacco smokers compared with participants who never smoked. Variations beta(2)*-nAChR availability during course abstinence may be related to urge smoke, extent nicotine withdrawal, and successful abstinence.To examine changes acute prolonged from smoking determine how were clinical features smoking.Tobacco participated up 4 iodide 123-labeled 5-iodo-A-85380...
Marijuana use in adolescents is associated with many adverse outcomes, including neurobiological and health consequences. Despite this, little known about gender differences the correlates of adolescent marijuana use. This study attempted to fill this gap by examining lifetime past 30-day Data from a cross-sectional statewide survey risk behavior participation Connecticut were analyzed using χ2 hierarchical logistic regression methodologies examine demographic, psychosocial, Gender-by-trait...
Many e-cigarette users find the variety of flavors appealing. We examined whether preferences for e-liquid and total number preferred differed between samples adolescent adult users. also these were associated with use frequency adolescents or adults, respectively.The analytic comprised 1) 396 adolescent, past-month from 5 Connecticut high schools who completed an anonymous, school-based survey in Fall 2014 (56.1% male; 16.18 [1.18] years; 42.2% smokers), 2) 590 adult, MTurk (53.7% 34.25...
BACKGROUND AND OBJECTIVES: Electronic cigarette (e-cigarette) use is associated with initiation among adolescents. However, it unclear whether e-cigarette more frequent after initiation. Also, the extent to which or dual and users transition exclusive nonuse of either product not yet known. METHODS: Data were pooled from 3 prospective cohort studies in California Connecticut (baseline: 2013–2014; follow-up: 2014–2016; N = 6258). Polytomous regression models used evaluate association baseline...