Crataegus pinnatifida is used to treat various diseases, including indigestion, congestive heart failure, hypertension, atherosclerosis, and myocardial dysfunction. We evaluated antioxidant anti-α-glucosidase activities of solvent extracts major bioactive components from the fruit C. pinnatifida. Ethyl acetate showed potent with IC50 values 23.26 ± 1.97 50.73 8.03 μg/mL, respectively, in DPPH ABTS radical scavenging assays. Acetone extract exhibited significant activity 42.35 2.48 μg/mL....

Portulaca oleracea is a well-known species for traditional medicine and food homology in Taiwan. In medicine, P. also used to treat gastrointestinal disorders, liver inflammation, fever, severe headaches. We investigated antioxidant, anti-tyrosinase, anti-α-glucosidase activities of various solvent extracts major bioactive components from oleracea. Ethanol acetone showed potent DPPH, ABTS, hydroxyl radical scavenging activities. Chloroform n-hexane displayed significant superoxide activity....

Polygonatum sibiricum (Asparagaceae) is often used as an herbal drug in the traditional medicine of Southeast Asia. Its rhizome, called "Huang Jing", Chinese immune system stimulant, hypolipidemic agent, anti-aging anti-fatigue and cardiovascular protectant. We investigated antioxidant, anti-acetylcholinesterase (AChE), anti-inflammatory, anti-α-glucosidase effects various solvent extracts major bioactive components (PS) processed (PPS). Dichloromethane extract PS showed stronger antioxidant...

Helminthostachys zeylanica (L.) Hook. is plant that has been used in traditional Chinese medicine for centuries the treatment of inflammation, fever, pneumonia, and various disorders. The aims present study are to figure out possible effectiveness component Ugonin M, a unique flavonoid isolated from H. zeylanica, elucidate mechanism(s) by which it works LPS-induced ALI model. In this study, M not only inhibited production pro-inflammatory mediators such as NO, TNF-α, IL-1β, IL-6, well...

The root bark of Morus alba L. (Mori Cortex) is used to treat diuresis and diabetes in Chinese traditional medicine. We evaluated different solvent extracts bioactive components from the for their antioxidant, anti-α-glucosidase, antityrosinase, anti-inflammatory activities. Acetone extract showed potent antioxidant activity, with SC50 values 242.33 ± 15.78 129.28 10.53 µg/mL DPPH ABTS radical scavenging assays, respectively. ethyl acetate exhibited strongest anti-α-glucosidase IC50 3.87...

Four new compounds, including two dihydroagarofuranoid sesquiterpenes, 8-benzoyloxymutangin (1) and 15-acetoxyorbiculin G (2), a lignan derivative, 9,9′-O-di-(Z)-feruloyl-(−)-secoisolariciresinol (3), benzenoid, 5′-methoxyevofolin B (4), have been isolated from the stem of Microtropis japonica, together with 20 known compounds (5−24). 3-Ethoxy-4-hydroxybenzaldehyde (5) was identified natural source for first time. The structures these were determined through analyses physical data....

The dried root of Ampelopsis japonica (Thunb.) Makino (A. japonica.) is a traditional medicine used to treat fever, pain, and wound healing. It exhibits anti-inflammatory, antitumor, antityrosinase, antimelanogenic activities. In this paper, we different solvent extracts from the A. determine their antioxidant activity. Acetone extract showed relatively strong properties by 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), 2,2-diphenyl-1-(2,4,6-trinitrophenyl)hydrazyl (DPPH),...

The purpose of this study was to screen firstly the potential effects antcin K (AnK), main constituent fruiting body Antrodia camphorata , in vitro and further evaluate activities mechanisms high‐fat‐diet‐ (HFD‐) induced mice. Following 8‐week HFD‐induction, mice were treated with AnK, fenofibrate (Feno), metformin (Metf), or vehicle for 4 weeks afterward. In C2C12 myotube cells, membrane GLUT4 phospho‐Akt expressions higher insulin AnK‐treated groups than control group. It observed that...

The rhizome of Anemarrhena asphodeloides Bunge (AA, family Liliaceae) is a famous and frequently used herbal drug in the traditional medicine Northeast Asia, under vernacular name "zhimu". A. has been as an anti-inflammatory, antipyretic, anti-platelet aggregation, anti-depressant, anti-diabetic agent Chinese medicine. We examined antioxidant, anti-acetylcholinesterase (AChE), anti-α-glucosidase activities various solvent extracts main bioactive compounds from asphodeloides. Acetone extract...

Lawsonia inermis Linn (Lythraceae), also known as henna, is a small shrub or tree distributed throughout Taiwan's Lanyu Island, in North Africa, and Australia. Its leaves are used folk medicine for the treatment of external hemorrhage fingernail abscesses. Investigation ethyl acetate (EtOAc)-soluble fractions from methanol extract aerial part has led to isolation new diphenol, (Z)-4,4'-(prop-1-ene-1,3-diyl)diphenol (1), two isocoumarin carbonates, inermiscarbonates A (2) B (3), six...

Three new triterpenoids—spergulagenin B (1), spergulagenin C (2), and D (3)—were isolated from the aerial part of Glinus oppositifolius, along with 17 known compounds (4–20). The structures these were identified by spectroscopic MS analyses. Compounds 3, 5, 19, 20 evaluated for inhibition nitric oxide production in LPS-stimulated RAW 264.7 cells IC50 values 17.03, 18.21, 16.30, 12.64 μM, respectively. exhibited inhibitory effects on LPS-induced 18.35 ± 1.34, 17.56 1.41, 14.27 1.29

Three new benzenoid derivatives, lawsoinermone (1), inermidioic acid (2), and inermic (3) have been isolated from the aerial part of Lawsonia inermis, together with 11 known compounds (4-14). The structures three were determined through spectroscopic MS analyses. Compounds 1, 4-6, 13 14 evaluated for inhibition nitric oxide production in LPS-stimulated product nitrite RAW 264.7 cells IC50 values 6.12, 16.43, 18.98, 9.30, 9.30 14.90 μg/mL, respectively.

A new bithiophene, 5-(4-hydroxy-3-methoxy-1-butyny)-2,2'-bithiophene (1), and sixteen known thiophenes: 2-(3,4-dihydroxybut-1-ynyl)-5-(penta-1,3-diynyl)thiophene (2), α-terthienyl (3), 5-(3,4-dihydroxybut-1-ynyl)-2,2'-bithiophene (4), 5-acetyl-2,2'-bithiophene (5), 5-formyl-2,2'-bithiophene (6), methyl 2,2'-bithiophene-5-carboxylate (7), 5-(but-3-en-1-ynyl)-2,2'-bithiophene (8), 5-(4-isovaleroyloxybut-1-ynyl)-2,2'-bithiophene (9), cardopatine (10), isocardopatine (11),...

Yi Mai Jian herbal formula (YMJ) is formulated with Eucommiae Folium, Astragali Radix, Ligustri Lucidi Fructus, and Elaeagnus Fructus to improve bone function in traditional Chinese medicine. The anti-osteoporotic effects of YMJ metabolism were evaluated ovariectomized (OVX) rats. skeletal structure the femur vertebrae was analyzed after treating OVX rats for 114 days. results showed that significantly increased mineral density (BMD) trabecular number (Tb. N) 5th lumbar reduced separation...