A5101618087- Epigenetics and DNA Methylation
- Intergenerational Family Dynamics and Caregiving
- Health disparities and outcomes
- Congenital Heart Disease Studies
- Employment and Welfare Studies
- Ultrasound in Clinical Applications
- Migration and Labor Dynamics
- Family Dynamics and Relationships
- Hemodynamic Monitoring and Therapy
- Demographic Trends and Gender Preferences
- Genomics and Chromatin Dynamics
- Early Childhood Education and Development
- Cardiac Valve Diseases and Treatments
- Toxic Organic Pollutants Impact
- Effects and risks of endocrine disrupting chemicals
- Carcinogens and Genotoxicity Assessment
- Liver physiology and pathology
- Identity, Memory, and Therapy
- FOXO transcription factor regulation
- Hedgehog Signaling Pathway Studies
- Cardiovascular Issues in Pregnancy
- Migration, Aging, and Tourism Studies
- Risk Perception and Management
- Family Support in Illness
- Parental Involvement in Education
Southwestern University of Finance and Economics
2019-2024
Jinan University
2015-2022
Sichuan Agricultural University
2022
Yangzhou University
2021
Southern Medical University
2021
Guangzhou Regenerative Medicine and Health Guangdong Laboratory
2019
National Marine Environmental Monitoring Center
2017
China National Environmental Monitoring Center
2017
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)
2017
Dongguan People’s Hospital
2015
Visualization of specific genomic loci in live cells is a prerequisite for the investigation dynamic changes chromatin architecture during diverse biological processes, such as cellular aging. However, current precision imaging methods are hampered by lack fluorescent probes with high specificity and signal-to-noise contrast. We find that conventional transcription activator-like effectors (TALEs) tend to form protein aggregates, thereby compromising their performance applications. Through...
Cadmium is an environmental pollutant that has extensive deleterious effects on the reproductive system. However, mechanisms underlying of cadmium preimplantation embryos are unclear. Here, we used a mouse model to investigate maternal (32 mg/l) exposure in drinking water for 2 days early embryonic development, and studied associated with epigenetic modifications DNA damage induced by oxidative stress. We observed impaired embryo development inducing death, fragmentation, or developmental...
Objective To determine the prevalence and clinical significance of heart murmurs detected during disease screening among apparently healthy schoolchildren. Design Cross-sectional study. Setting 32 elementary schools in Dongguan City China. Patients 81 213 schoolchildren aged 5–13 years from different schools. Main outcome measures The Results Murmurs were 2193 (2.7%), whom 215 had a structural (SHD). Of patients who SHD, 198 children congenital (CHD), 12 mitral valve prolapse 5 rheumatic...
The ultrasonographic evaluation of inferior vena cava (IVC) parameters, particularly the collapsibility index (CI), has been widely used in assessment fluid responsiveness critically ill patients, but results are conflicting. In this study, we aimed to investigate early change CI after increased intravascular volume (IVV) induced by passive leg raising (PLR). A total 145 healthy volunteers over 18 years old were enrolled between September and December 2015. Before 2 min PLR, maximum minimum...
Transmembrane protein 30A (Tmem30a) is the β-subunit of P4-ATPases which function as flippase that transports aminophospholipids such phosphatidylserine from outer to inner leaflets plasma membrane maintain asymmetric distribution phospholipids. It has been documented deficiency Tmem30a led exposure phosphatidylserine. However, role in vivo remains largely unknown. Here we found Vav-Cre-driven conditional deletion hematopoietic cells embryonic lethality due severe anemia by day 16.5. The...
Nutritional status plays an indispensable role in enhancing human capital and preventing the return to poverty. In context of three-child policy aging society China, intergenerational care will inevitably become a core component family support. Thus, this paper evaluates impacts behavior on nutritional intake Chinese rural residents from perspective household consumption. The study’s data is China Family Panel Studies (CFPS) (2010–2014), and, fixed effect model analyses are applied achieve...