A5043236819- Bacillus and Francisella bacterial research
- Animal Disease Management and Epidemiology
- Viral gastroenteritis research and epidemiology
- SARS-CoV-2 and COVID-19 Research
- Animal Virus Infections Studies
- Computational Drug Discovery Methods
- Plant Virus Research Studies
- Medicinal Plants and Neuroprotection
- Zoonotic diseases and public health
- Genomics and Phylogenetic Studies
- RNA and protein synthesis mechanisms
- Viral Infections and Vectors
- Lung Cancer Treatments and Mutations
- Poxvirus research and outbreaks
- Pharmacological Effects of Natural Compounds
- Animal Diversity and Health Studies
- Viral Infections and Immunology Research
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Transgenic Plants and Applications
- Mosquito-borne diseases and control
- Phytochemicals and Medicinal Plants
- Synthesis and biological activity
- Agricultural pest management studies
- Diverse Scientific Research Studies
National Institute Of Veterinary Epidemiology And Disease Informatics
2021-2025
Jawaharlal Nehru Medical College
2022-2024
Indian Council of Agricultural Research
2021-2022
Davangere University
2021
The present work describes a facile and convenient procedure for synthesizing zinc oxide nanoparticles using luteolin isolated from Eclipta alba plant (L-ZnONPs) at room temperature. formation of as-grown L-ZnONPs was confirmed by X-ray diffraction analysis (XRD), scanning electron microscopy (SEM), transmission (TEM), high-resolution (HR-TEM), selected area (SAED). Wurtzite structure ZnO observed its hexagonal phases in patterns. SEM images revealed the different sizes morphologies...
Porcine epidemic diarrhea (PED) is a significant pig disease causing high mortality in suckling pigs and morbidity across all age groups. It highly prevalent Southeast Asia, posing threat of transboundary transmission to India. Although antibodies were detected as early 2003 Assam, there was no evidence viral detection or molecular characterization until this study. This study reports the first clinical outbreak PED India, followed by genetic virus (PEDV) during 2022-23. The characterized,...
Lumpy skin disease (LSD) is a re-emerging viral transboundary affecting cattle and buffaloes, resulting in significant socio-economic impact on the affected regions. LSD primarily transmitted among susceptible livestock through hematophagous vectors, including ticks flies. Ticks also function as reservoirs for various haemoprotozoan parasites, increasing likelihood of coinfections animals. This study investigates comorbidity associated risk factors using diverse datasets. A total 414 samples...
<title>Abstract</title> Classical swine fever virus (CSFV) is a pathogen that affects pigs and wild boars. This contagious RNA high threat to industries throughout the world because it has mortality morbidity rates, leading economic losses. Although previous studies primarily focused on isolated regions or specific genotypes, our study leverages global dataset of 220 CSFV whole-genome sequences retrieved from NCBI repository along with2 complete genome sequence laboratory (Accession number:...
Background and Aim: Anthrax, caused by the soil-borne spore-forming bacteria called Bacillus anthracis, is a zoonotic disease that persists worldwide in livestock wildlife infects humans. It great hazard to livestock; henceforth, evaluating global concerns about occurrence essential. This study was conducted estimate prevalence of anthrax predict high-risk regions, which could be an input veterinarians take necessary steps control avoid disease. Materials Methods: A literature review...
Bacillus anthracis is the bacterium responsible for causing zoonotic disease called anthrax. The presents itself in different forms like gastrointestinal, inhalation, and cutaneous. Bacterial spores are tremendously adaptable, can persist extended periods occasionally endanger human health. Anthrax Toxin Receptor-2 (ANTXR2) gene acts as membrane receptor facilitates entry of anthrax toxin into host cells. Additionally, mutations ANTXR2 have been linked to various autoimmune diseases,...
The outbreak of novel coronavirus strain (Covid-19) with a high pandemic threat has predict grave public health and economic concerns. This virus, originating from the Wuhan region in China spread worldwide affecting millions no registered persuasive targeted therapy. In this paper, we analyze three important proteins encoded by envelope protein 5 × 29, RNA binding nucleocapsid 1SSK, spike glycoprotein 6ACD, for an effective virion accumulation, remdesivir was first drug approved FDA EMA...
The edible parts of the plants Camellia sinensis, Vitis vinifera and Withania somnifera were extensively used in ancient practices such as Ayurveda, owing to their potent biomedical significance. They are very rich secondary metabolites polyphenols, which good antioxidants exhibit anti-carcinogenic properties. This study aims evaluate anti-cancerous properties these plant crude extracts on human liver cancer HepG2 cells. leaves seeds collected methanolic prepared. Then, subjected DPPH, α-...
The spike (S) glycoprotein and nucleocapsid (N) proteins are the crucial pathogenic of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) virus during its interaction with host. Even FDA-approved drugs like dexamethasone grazoprevir not able to curb viral progression inside host reported adverse effects on body metabolism. In this context, we aim report corilagin a novel, potential dual inhibitor S N from Terminalia chebula. bioactive compounds T. chebula were subjected series...
In the recent survey, Japanese encephalitis (JE) is one of most common mosquito-borne diseases, accounting for ∼30% fatalities. The outbreaks JE virus (JEV) suggests that exhaustive study essential prevention and management disease. disease mainly spreads in humans pigs by vector: mosquito; as this a major concern, had employed various bioinformatics tools to investigate codon usage bias, evolutionary inference selection pressure analysis results indicated was biased natural main factor...
Lablab purpureus from the Fabaceae family has been reported to have antiviral properties and used in traditional medical systems like ayurveda Chinese medicine employed treat a variety of illnesses including cholera, food poisoning, diarrhea, phlegmatic diseases. The bovine alphaherpesvirus-1 (BoHV-1) is notorious for causing significant harm veterinary agriculture industries. removal contagious BoHV-1 host organs, particularly those reservoir creatures, required use drugs that target...
Anthrax, a globally significant disease, poses substantial threats to both livestock and human populations. Timely identification of anthrax outbreaks is paramount mitigate its impact on animal health, public safety. This study aims construct predictive model for disease occurrence. By leveraging the potential advanced Machine-Learning techniques, we projected likelihood across India, through incorporating diverse set meteorological, remote sensing parameters. The ultimate goal establish...
Anthrax is a highly fatal zoonotic disease that affects all species of livestock. The study aims to develop an early warning epidemiological anthrax using machine learning (ML) models and the effect El Niño La Niña oscillation, as well climate–disease relationship concerning spatial occurrence outbreaks in Karnataka. incidence data are divided based on events from 2004–2019 subjected climate-disease modeling understand pattern over years. Machine were implemented R statistical software...
Bacterial infections are one of the leading causes morbidity, mortality, and healthcare complications in patients. Leptospirosis is found to be most prevalent, re-emergent, neglected tropical zoonotic disease worldwide. The adaptation various environmental conditions has made Leptospira acquire a large genome (~4.6 Mb) complex outer membrane, making it unique among bacteria that mimic symptoms jaundice hemorrhage. Sph2 another important virulence factor enhances hemolytic...
Computational databases and tools in recent times have been proved to provide an essential aid for anticancer studies the field of oncology. Molecular docking facilitate structural diversity plant-derived phytomolecules having properties against receptor proteins involved cancer signaling pathways. The current study involves investigation phytocompounds-agasthisflavone, anacardic acid, zoapatanolide A, a purified product plant extract Amarogopinois546 were subjected on p38-α MAPK EGFR Kinase...
There is a shred of evidence to suggest that Emblica officinalis Gaertn, the botanical name for amla seeds, has greater medicinal potential than fruit. We conducted this work assess anti-inflammatory, antibacterial, and antioxidant capacities E. seed extracts. The bioactive components from seeds were fractionated using chloroform, hexane, methanol, diethyl ether, according polarity solvents. total amount phenolic flavonoid was estimated. Both reducing power extracts evaluated DPPH...
Background: The ubiquitous proteases that are commonly found in all living organisms play an important role cell growth and differentiation. bacterium Bacillus thuringiensis (Bt) produces delta-endotoxins exhibit toxic properties against various insecticides has demonstrated its potency safety as a biopesticide agent for decades. Bt protein includes vegetative, insecticidal, crystal proteins highly toxicants immature insects (larvae). Objectives: aim of this research was to use alternative...
Nosocomial infections are a notorious subset of infectious diseases, varying between 10% and 20% prevalence worldwide. The concomitant with various treatment complications, multiple-drug resistance, high degree virulence. Klebsiella pneumoniae is gram-negative bacteria nosocomial importance. Our current study gauged to reason understand why, despite cutting-edge medicines technology, the K. remains elusive. Using in silico tools, KPHS_00890 hypothetical protein subsp. HS11286 was identified...