A5026252814- Animal Disease Management and Epidemiology
- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Virus-based gene therapy research
- Vector-Borne Animal Diseases
- Brucella: diagnosis, epidemiology, treatment
- Microbial infections and disease research
- Influenza Virus Research Studies
- Immune Cell Function and Interaction
- Salmonella and Campylobacter epidemiology
- Animal Diversity and Health Studies
- Bacteriophages and microbial interactions
- Inflammation biomarkers and pathways
- T-cell and Retrovirus Studies
- Poxvirus research and outbreaks
- Helminth infection and control
- vaccines and immunoinformatics approaches
- Plant Virus Research Studies
- Coccidia and coccidiosis research
- Medicinal Plant Research
- Mycobacterium research and diagnosis
- Immune cells in cancer
- Animal health and immunology
- Livestock and Poultry Management
National Institute Of Veterinary Epidemiology And Disease Informatics
2016-2025
Karnataka Veterinary Animal and Fisheries Sciences University
2021
The Ohio State University
2013-2020
Indian Council of Agricultural Research
2016-2018
<title>Abstract</title> Classical swine fever virus (CSFV) is a pathogen that affects pigs and wild boars. This contagious RNA high threat to industries throughout the world because it has mortality morbidity rates, leading economic losses. Although previous studies primarily focused on isolated regions or specific genotypes, our study leverages global dataset of 220 CSFV whole-genome sequences retrieved from NCBI repository along with2 complete genome sequence laboratory (Accession number:...
Abstract Salmonella continues to be a major food safety and public health threat. In the present study, enterica subsp. serotypes Enteritidis (SE) Typhimurium (ST) were isolated from poultry characterized for virulence, antimicrobial susceptibility, biofilm formation. Prevalence of in was 3.35%; predominant S . (68.1%) (31.8%). Source‐wise, retail market chicken meat (4.8%), live at farm (2.5%), table eggs (2.1%). isolates produced inv A gene 284 bp (100%), spv R 310 (77.27%), C 571...
ABSTRACT Porcine reproductive and respiratory syndrome virus (PRRSV) nonstructural protein 1β (nsp1β) is a multifunctional viral protein, which involved in suppressing the host innate immune response activating unique −2/−1 programmed ribosomal frameshifting (PRF) signal for expression of products. In this study, site-directed mutagenesis analysis showed that R128A or R129A mutation introduced into highly conserved motif ( 123 GKYLQRRLQ 131 ) reduced ability nsp1β to suppress interferon beta...
Porcine epidemic diarrhea virus (PEDV) is an economically devastating enteric disease in the swine industry. The infects pigs of all ages, but it cause severe clinical neonatal suckling with up to 100% mortality. Currently, available vaccines are not completely effective and feedback methods utilizing PEDV infected material has variable success preventing reinfection. Comprehensive information on levels duration effector/memory IgA IgG antibody secreting B cell response intestines lymphoid...
Swine brucellosis is a zoonotic disease caused by Brucella suis. The study describes the occurrence of in two organized piggeries Southern India.A total 585 serum samples comprising 575 from pigs and 10 animal handlers were collected tested serological tests PCR. Tissue for isolation pathogen.Out screened, 236 (41.04%) positive both Rose Bengal plate test (RBPT) indirect ELISA (iELISA) 47 (8.17) showed DNA amplification genus specific sows those aborted 19 boars with orchitis seropositive...
Abstract Bovine coronavirus (BCoV) poses a significant threat to the global cattle industry, causing both respiratory and gastrointestinal infections in populations. This necessitates development of efficacious vaccines. While several inactivated live BCoV vaccines exist, they are predominantly limited calves. The immunization adult is imperative for infection control, as it curtails viral transmission calves ameliorates impact enteric ailments across all age groups within herd. study...
ABSTRACT Porcine reproductive and respiratory syndrome virus (PRRSV)-specific neutralizing antibodies (NA) are important for clearing the virus. Pen-based pig oral fluid samples disease surveillance gaining in importance due to ease of collection low cost. The aim this study was develop a PRRSV-specific NA assay determine titers samples. At first, we standardized PRRSV using pen-based collected over period 3 months from herd swine that received modified live vaccine (PRRS-MLV), also used...
Porcine reproductive and respiratory syndrome (PRRS) is caused by PRRS virus (PRRSV), which infects primarily the tract of pigs. Thus intranasal (IN) delivery a potent vaccine-adjuvant formulation promising. In this study, PRRS-MLV (VR2332) was coadministered ± an adjuvant Mycobacterium vaccae whole cell lysate or CpG ODN through intramuscular (IM) IN route as mist, challenged with heterologous PRRSV 1-4-4 at 42 days post-vaccination (dpv). At 14 26 dpv, vaccine viral RNA copies were one log...
Porcine reproductive and respiratory syndrome (PRRS) is a disease endemic in many countries of economic importance. India was free from PRRS until the first outbreak reported North-East Indian state 2013. Since then, outbreaks have been pilot study conducted earlier showed that it gradually spreading to rest India. Considering there are no locally developed population screening tests available for imported diagnostic/screening expensive, present aimed at developing recombinant nucleocapsid...
The whole-genome sequence of an Indian field isolate classical swine fever virus, NIVEDI-165, was found to be subtype 1.1, and it showed 89 99% amino acid identity 84 nucleotide with four five virus (CSFV) isolates, respectively. To the best our knowledge, this is first report on a full-genome CSFV from South India.
Torque teno viruses (TTVs) are circular, single-stranded DNA viruses, which infect a wide range of animals including livestock and companion animals. Swine TTVs (torque sus [TTSuVs]) thought to act as primary or coinfecting pathogen in pathological conditions such porcine dermatitis nephropathy syndrome post-weaning multisystemic wasting syndrome. So far, the presence virus has not been reported India. Considering that TTSuVs have potential cross species barrier into humans pork consumption...
Abstract Swine influenza virus (SwIV) causes considerable economic loss to pig industry, and some SwIV are zoonotic. This study was conducted evaluate the cross-protective efficacy of PLGA (poly lactic-co-glycolic acid) nanoparticles (NPs) encapsulated vaccine in pigs. Killed H1N2 (δ lineage) antigens (KAg) were NPs 200–300 nm (PLGA-KAg NPs), antibody-free pigs prime-boost vaccinated intranasally as mist challenged using a heterologous, virulent zoonotic H1N1 (γ lineage). PLGA-KAg induced...
Infectious bovine rhinotracheitis (IBR) is an infectious disease caused by BoHV-1 and belongs to the Herpesviridae family. IBR endemic in India including north eastern states of country. Hence study was undertaken understand seroprevalence parts A total 3125 cattle (Holstein Friesian crossbred) serum samples from 35 districts five (Assam, Manipur, Meghalaya, Mizoram, Sikkim) were screened for virus antibodies using Avidin biotin ELISA. two-stage random sampling methodology followed...
Abstract Non‐typhoidal Salmonella serotypes continue to be major food safety and public health threats worldwide. In the era of emerging antimicrobial resistance, it is imperative search for alternative strategies infection control. Present study deals with passive protection young chicks using polyclonal egg yolk antibodies (IgY). Laying hens were actively immunized heat inactivated enterica subsp. S . Enteritidis (SE) Typhimurium (ST) isolated from poultry. Serotype specific IgY hen...
Infectious bovine rhinotracheitis (IBR) is a highly contagious disease of bovines causing respiratory symptoms, abortions, and reduced milk yield, leading to huge economic losses. Reports on seroprevalence in India are available restricted districts/states. In the present study, nationwide IBR was conducted provide national Chief Veterinarian who turn can design control strategies. A total 15,592 cattle buffalo serum samples from 25 states 3 Union Territories viz., Jammu Kashmir, Puducherry,...