- Animal Disease Management and Epidemiology
- Vector-Borne Animal Diseases
- Viral Infections and Immunology Research
- Animal Virus Infections Studies
- Mycobacterium research and diagnosis
- Brucella: diagnosis, epidemiology, treatment
- Microbial infections and disease research
- Milk Quality and Mastitis in Dairy Cows
- Viral Infections and Vectors
- Poxvirus research and outbreaks
- Animal Diversity and Health Studies
- Viral gastroenteritis research and epidemiology
- Aquaculture disease management and microbiota
- Herpesvirus Infections and Treatments
- Phytase and its Applications
- Antibiotic Resistance in Bacteria
- Pharmaceutical and Antibiotic Environmental Impacts
- Coccidia and coccidiosis research
- Parasite Biology and Host Interactions
- Enzyme Production and Characterization
- Virus-based gene therapy research
- Cancer Research and Treatments
- Influenza Virus Research Studies
- Reproductive Physiology in Livestock
- Helminth infection and control
Indian Council of Agricultural Research
2015-2023
ICAR-Indian Institute of Agricultural Biotechnology
2023
National Institute Of Veterinary Epidemiology And Disease Informatics
2020
Lala Lajpat Rai University of Veterinary and Animal Sciences
2018
Punjab Agricultural University
1988-2017
Indian Council of Medical Research
2017
Temple University Health System
2017
Indian Veterinary Research Institute
2015
On March 24 and 25, 2017 researchers clinicians from around the world met at Temple University in Philadelphia to discuss current knowledge of Mycobacterium avium ssp. Paratuberculosis (MAP) its relationship human disease. The conference was held because shared concern that MAP is a zoonotic bacterium poses threat not only animal health but also health. In order further study this problem, conferees discussed ways improve diagnostic tests potential future anti-MAP clinical trials....
Lumpy skin disease (LSD) was reported for the first time in India 2019 and since then, it has become endemic. Since a homologous (LSD-virus based) vaccine not available country, goatpox virus (GPV)-based heterologous authorized mass immunization to induce protection against LSD cattle. This study describes evaluation of safety, immunogenicity efficacy new live-attenuated developed by using an Indian field strain, isolated from The attenuated continuous passage (P = 50) Vero cells. (50th LSDV...
Microbial keratinases exhibit a momentous role in converting keratin biowastes into exceedingly valuable protein supplements. This study reports novel, highly stable keratinase from Bacillus pacificus RSA27 for the production of pure peptides rich essential amino acids chicken feathers. Purified showed specific activity 38.73 U/mg, 2.58-fold purification, and molecular weight 36 kDa. Kinetic studies using feather as substrate report Km Vmax values 5.69 mg/ml 142.40 μg/ml/min, respectively,...
Examination of samples stool from a 61-year-old male patient, presenting with the clinical symptoms Crohn's disease (CD), revealed massive shedding acid fast bacilli morphology Mycobacterium avium paratuberculosis (MAP), causative agent Johne's in cattle. MAP was cultured stool. Biotyping bacterium isolated cultures demonstrated, it Indian Bison biotype MAP, dominant infecting livestock and humans India. Based on this finding because patient unresponsive to standard therapy used India treat...
Equine influenza viruses (EIV)—H3N8 continue to circulate in equine population throughout the world. They evolve by process of antigenic drift that leads substantial change antigenicity virus, thereby necessitating substitution virus strain vaccines. This requires frequent testing new vaccines vivo system; however, lack an appropriate laboratory animal challenge model for protective efficacy vaccine candidates hinders screening and other therapeutic approaches. In present investigation,...
A systematic vaccination programme is ongoing in India to control the three prevailing serotypes (A, O, Asia1) of foot-and-mouth disease (FMD) virus. Under programme, more than 120 million bovine (term applicable both cattle and buffalo this study) population 221 666 districts country are being bi-annually vaccinated with trivalent vaccine since 2010. Although clinical has reduced these because vaccinations, an abrupt increase number FMD cases was recorded 2013. Hence, a longitudinal field...
Wild-type adult mice with intact interferon (IFN) system were neither susceptible to bluetongue virus (BTV) infection nor showed signs of morbidity/mortality. Establishment immunologically competent wild-type mouse model type I IFNs blockade is necessary assess the pathogenesis, immune responses and testing BTV vaccines. Present study aimed establish characterize serotype 1 in immunocompetent at time by studying sequential pathology. Adult administered anti-mouse IFN-α/β receptor subunit-1...
Porcine brucellosis is a contagious and emerging zoonosis but neglected in most of the endemic countries including India. The disease pigs rarely reported due to non-availability diagnostics or major focus on bovine brucellosis. Hence, necessity was felt develop indirect ELISA for detection anti-Brucella antibodies record spatial seroprevalence porcine country. relative diagnostic sensitivity specificity developed were 94.0% 92.0%, respectively kappa agreement with rose bengal plate test,...
Culicoides are important vectors for livestock and human pathogens. Wild animals act as reservoirs orbiviruses such bluetongue African horse sickness viruses. There only limited studies on the distribution of species in forest habitats. In this study, we collected from different wildlife sanctuaries national parks Karnataka. We morphologically identified 8597 Culicoides. found 18 sites, with C. oxystoma imicola being predominant across sites. The sequence alignment phylogenetic analysis Cox1...
ABSTRACT Lumpy skin disease (LSD) was reported for the first time in India 2019 and since then, it has become endemic. Since a homologous (LSD-virus based) vaccine not available country, goatpox virus (GPV)-based heterologous authorized mass immunization against LSD cattle. This study describes evaluation of safety, immunogenicity efficacy new live-attenuated developed using an Indian field strain (LSDV/India/2019/Ranchi). The attenuated by continuous passage (P=50) Vero cells. (50 th LSDV...
The present study was undertaken to see the excretion of FMD virus in milk during and after subset outbreak. Fore-milk (50 ml) sampled from 12 clinically infected 3 asymptomatic cows morning. Analytical sensitivity NAR methods estimated using uninfected negative sample spiked with 105.7 TCID50/ml serotype O (IND R2/1975) 10 fold serial dilution. Detection limit mPCR RT- LAMP assay 102.7 101.7 TCID50/ml, respectively. 15 individual pooled cows’ samples were processed for isolation (VI)...