Chris Vercammen
A5047211412- Gestational Diabetes Research and Management
- Diabetes Management and Research
- Bariatric Surgery and Outcomes
- Pregnancy and preeclampsia studies
- Pancreatic function and diabetes
- Diabetes and associated disorders
- Diabetes Treatment and Management
- Birth, Development, and Health
- Lipoproteins and Cardiovascular Health
- Diabetes Management and Education
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Metabolism, Diabetes, and Cancer
- Obesity, Physical Activity, Diet
- Maternal Mental Health During Pregnancy and Postpartum
- Obesity and Health Practices
- Blood Pressure and Hypertension Studies
- Breastfeeding Practices and Influences
- Adipose Tissue and Metabolism
- Pregnancy-related medical research
- Cardiac Health and Mental Health
- Eosinophilic Disorders and Syndromes
- Cancer Risks and Factors
- Cell Adhesion Molecules Research
- Skin Diseases and Diabetes
- Chronic Kidney Disease and Diabetes
Imelda Hospital
2014-2025
Universitair Ziekenhuis Leuven
2021
KU Leuven
1987-2021
Onze Lieve Vrouwziekenhuis Hospital
2021
Novo Nordisk (Denmark)
2019
Clinical Research Institute
2018
Duke University
2018
San Francisco VA Medical Center
2016
Institute of Nutrition, Metabolism and Diabetes
1994
OBJECTIVE This study evaluated the long-term safety and efficacy of dapagliflozin as an adjunct to adjustable insulin in patients with type 1 diabetes inadequate glycemic control. RESEARCH DESIGN AND METHODS DEPICT-1 (Dapagliflozin Evaluation Patients With Inadequately Controlled Type Diabetes) was a randomized (1:1:1), double-blind, placebo-controlled phase 3 5 mg 10 (HbA1c 7.5–10.5% [58–91 mmol/mol]) (NCT02268214). The results 52-week study, consisting 24-week short-term 28-week extension...
Randomized controlled trials evaluating real-time continuous glucose monitoring (RT-CGM) patients with type 1 diabetes (T1D) show improved glycemic control, but limited data are available on real-world use. To assess impact of RT-CGM in settings hospital admissions, work absenteeism, and quality life (QOL). Prospective, observational, multicenter, cohort study. A total 515 adults T1D subcutaneous insulin infusion (CSII) therapy starting the Belgian reimbursement program. Initiation...
Abstract Purpose Real-time continuous glucose monitoring (RT-CGM) provides information on glycemic variability (GV), time in range (TIR), and guidance to avoid hypoglycemia, thereby complimenting HbA1c for diabetes management. We investigated whether GV TIR were independently associated with chronic acute complications. Methods Between September 2014 January 2017, 515 subjects type 1 using sensor-augmented pump therapy followed 24 months. The link between baseline CGM-derived glucometrics...
The International Association of Diabetes and Pregnancy Study Groups (IADPSG) recommends a universal one-step screening strategy with the 75-g oral glucose tolerance test (OGTT) for gestational diabetes mellitus (GDM) (1). Since adoption IADPSG recommendation by World Health Organization (WHO), criteria are commonly referred to as 2013 WHO (2). remains controversial due significant increase in GDM prevalence, increased workload, need fasting test, risk medicalization care (3). Several...
Since many European countries use risk factor screening for gestational diabetes mellitus (GDM), we aimed to determine the performance of selective GDM based on 2013 WHO criteria.Overall, 1811 women received universal with a 75 g oral glucose tolerance test (OGTT) in 12.5% (n = 231) criteria. We retrospectively applied different guidelines this cohort and evaluated clinical factors screen GDM.By applying English, Irish, French Dutch screening, respectively 28.5% 526), 49.7% 916), 48.5% 894)...
This study determines if a modified two-step screening strategy with glucose challenge test (GCT) ≥ 7.2 mmol/L and clinical risk factors improves the diagnostic accuracy for gestational diabetes mellitus (GDM), based on 2013 WHO criteria, while limiting number of oral tolerance tests (OGTT). was prospective multicentric cohort 1811 participants receiving both GCT 75 g OGTT in pregnancy. Participants health care providers were blinded GCT. Characteristics analyzed across four groups: abnormal...
OBJECTIVE In recent years, a growing number of people with type 1 diabetes gained access to real-time continuous glucose monitoring (rtCGM). Long-term benefits rtCGM are unclear because lack large studies long duration. We evaluated whether real-world use up 24 months offered benefits, particularly in those living impaired awareness hypoglycemia (IAH). RESEARCH DESIGN AND METHODS This 24-month, prospective, observational cohort study followed 441 adults insulin pumps receiving full...
Abstract Aims To determine the impact of depressive symptoms on pregnancy outcomes and postpartum quality life in women with gestational diabetes mellitus (GDM) normal glucose tolerance (NGT). Methods 1843 from a prospective cohort study received universal GDM screening an oral test (OGTT). The Center for Epidemiologic Studies–Depression questionnaire was completed before diagnosis communicated early postpartum. All participants 36-Item Short Form Health Survey (SF-36) health survey Results...
The International Association of Diabetes and Pregnancy Study Groups (IADPSG) recommends universal screening with a 75 g oral glucose tolerance test (OGTT) using stricter criteria for gestational diabetes (GDM). This may lead to important increases in the prevalence GDM associated costs, whereas gain health is unclear. goal 'The Belgian Study' (BEDIP-N) evaluate best strategy pregestational early pregnancy an ethnically diverse western European population. IADPSG will be followed, but...
Predictors for glucose intolerance postpartum were evaluated in women with gestational diabetes mellitus (GDM) based on the 2013 World Health Organization (WHO) criteria. 1841 tested GDM a prospective cohort study. A 75g oral tolerance test (OGTT) was performed at 14 ± 4.1 weeks. Of all 231 mothers GDM, 83.1% (192) had OGTT of which 18.2% (35) intolerance. Women more often Asian origin [15.1% vs. 3.7%, OR 4.64 (1.26–17.12)], recurrent history [41.7% 26.7%, 3.68 (1.37–9.87)], higher fasting...
Screening for gestational diabetes mellitus (GDM) is important to improve pregnancy outcomes and prevent type 2 after pregnancy. The ‘International Association of Diabetes Pregnancy Study Groups’ (IADPSG) recommends a universal one-step approach with the 75 g oral glucose tolerance test (OGTT) screening GDM. IADPSG recommendation remains controversial due increase in GDM prevalence increased workload. After review latest evidence based on data from ‘Belgian Pregnancy’ study, members Liga,...
To investigate whether single use of 4 mm needles combined with education about injection technique and lipohypertrophy affects HbA1c, hypoglycaemia glucose variability.Insulin-injecting people diabetes recruited from nine Belgian centres were prospectively followed for 6 months. They provided pen concerning using an online platform (BD Me™) based on the international Forum Injection Technique & Therapy Recommendations focused avoidance zones reduction needle reuse.A total 171 included which...
Aim: To determine the association between thyroid function and risk of developing gestational diabetes mellitus (GDM) adverse pregnancy outcomes. Methods: This case−control study was a sub-analysis BEDIP-N study, in which 199 GDM women were matched for age body mass index with 398 controls. Thyroid-stimulating hormone (TSH), free thyroxine (fT4), triiodothyronine (fT3), peroxidase (TPO) antibodies measured at 6−14 weeks 26−28 during pregnancy. TSH fT4 also early postpartum women. Results:...
More data are needed on the potential benefits and risks of gestational weight gain (GWG) less than recommended excessive GWG in women with diabetes (GDM) compared to normal glucose tolerance (NGT) during pregnancy.This work aimed evaluate association as low, within, or above (excessive) according Institute Medicine (IOM) guidelines, pregnancy outcomes (NGT).This prospective cohort study included 7 Belgian hospitals 1843 receiving universal GDM screening a 75-g oral test. Pregnancy...
Abstract Aims To determine impact of mild fasting hyperglycemia in early pregnancy (fasting plasma glucose [FPG] 5.1-5.5 mmol/L) on outcomes. Methods We measured FPG at 11.9 ± 1.8 weeks 2006 women from a prospective cohort study. Women with ≥5.6 mmol/L (19) received treatment and were excluded further analyses. A total 1838 <5.6 75 g oral tolerance test (OGTT) between 24 28 pregnancy. Results Of all participants, 78 (4.2%) had 5.1 to 5.5 pregnancy, which 49 normal OGTT later (high...