Valeria Denninghoff

ORCID: 0000-0002-3309-7801
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About
Contact & Profiles
Research Areas
  • Lung Cancer Treatments and Mutations
  • Cancer Genomics and Diagnostics
  • RNA modifications and cancer
  • Cutaneous Melanoma Detection and Management
  • Cancer Cells and Metastasis
  • Lung Cancer Research Studies
  • Cervical Cancer and HPV Research
  • Genetic factors in colorectal cancer
  • Cancer Immunotherapy and Biomarkers
  • Helicobacter pylori-related gastroenterology studies
  • Cancer Diagnosis and Treatment
  • Colorectal Cancer Treatments and Studies
  • Chronic Lymphocytic Leukemia Research
  • Lung Cancer Diagnosis and Treatment
  • Gastrointestinal disorders and treatments
  • Breast Cancer Treatment Studies
  • Lymphoma Diagnosis and Treatment
  • Metabolism and Genetic Disorders
  • Cancer and Skin Lesions
  • Neuroendocrine Tumor Research Advances
  • Lymphadenopathy Diagnosis and Analysis
  • Eosinophilic Esophagitis
  • Occupational and environmental lung diseases
  • Tumors and Oncological Cases
  • Gastric Cancer Management and Outcomes

University of Buenos Aires
2006-2024

Consejo Nacional de Investigaciones Científicas y Técnicas
2013-2024

Universidade Federal do Ceará
2024

Instituto de Biomedicina de Sevilla
2024

Hospital Universitario Virgen del Rocío
2024

Universidad de Sevilla
2024

Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research
2023-2024

Instituto de Investigación Biosanitaria de Granada
2023

Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno
2007-2020

Centro Científico Tecnológico - San Juan
2020

Helicobacter pylori is a curved microaerophilic Gram-negative bacterium considered as risk factor for gastric cancer. The aim of this study was to find an association between burning sensations, acid taste, halitosis, and lingual hyperplasia with the effect H. on mouth.A total 124 subjects different diseases were studied: 46 patients burning, halitosis dorsum 78 other diseases.The detection in oral cavity by histopathologic diagnosis molecular biology confirmed 40/46 (87%) hyperplasia, 2/78...

10.1111/j.1523-5378.2005.00322.x article EN Helicobacter 2005-08-01

Effective biomarkers are needed to enable personalized medicine for pancreatic cancer patients. This study analyzes the prognostic value, in early cancer, of single circulating tumor cell (CTC) and CTC clusters from central venous catheter (CVC) portal blood (PV).In total, 7 mL PV CVC 35 patients with were analyzed. isolated using a positive immunomagnetic selection. The detection identification performed by immunocytochemistry (ICC) analyzed Epi-fluorescence confocal microscopy.CTC detected...

10.3390/cancers13246153 article EN Cancers 2021-12-07

<b><i>Objective:</i></b> Latin American countries are heterogeneous in terms of lung cancer incidence and exposure to potential carcinogens. We evaluated the frequency clinical characteristics <i>ALK</i> rearrangements (<i>ALKr</i>) America. <b><i>Methods:</i></b> A total 5,130 patients from 10 were screened for inclusion. <i>ALKr</i> detection was performed by fluorescence situ hybridization (FISH),...

10.1159/000493733 article EN Oncology 2018-11-26

Abstract Background After skin cancer, breast cancer is the most common malignancy in women. Tumors of unknown origin account for 5-15% malignant neoplasms, with 1.5% being cancer. An immunohistochemical panel conventional and newer markers, such as mammaglobin, was selected detection neoplastic cells origin. The specific objectives are: 1) to determine sensitivity specificity panel, a special emphasis on inclusion mammaglobin marker, 2) compare immunohistochemistry performed whole tissue...

10.1186/1746-1596-7-73 article EN cc-by Diagnostic Pathology 2012-06-22

Lung cancer is the leading cause of cancer-related death worldwide. Recent advances in management non-small cell carcinoma are focused on discovery targeted therapies and novel immunotherapy strategies for patients with advanced disease. Treatment anti PD-(L)1 immune checkpoint inhibitors requires development predictive biomarkers to select those that can most benefit from these therapies. Several immunohistochemical have been developed different technological platforms. However, useful...

10.1016/j.heliyon.2020.e04117 article EN cc-by-nc-nd Heliyon 2020-06-01

Lymph node mapping and sentinel lymph biopsy are currently used to stage patients with cutaneous malignant melanoma. Immunohistochemical stains contribute the detection of micrometastases; however, molecular biology techniques associated better diagnostic sensitivity. Sixty nodes were included in this study. The primary lesions melanoma I or II, a follow-up longer than 2 years. Sentinel studied hematoxylin-eosin, immunohistochemistry for S-100 HMB-45, (reverse transcription (RT)-PCR)...

10.1038/modpathol.3801020 article EN publisher-specific-oa Modern Pathology 2008-01-25

Log in or Register Subscribe to journalSubscribe Get new issue alertsGet alerts Enter your Email address: Wolters Kluwer Health may email you for journal and information, but is committed maintaining privacy will not share personal information without express consent. For more please refer our Privacy Policy. eTOC Secondary Logo Journal All Articles Images Videos Podcasts Blogs Advanced Search Toggle navigation Login & Issues Current IssuePrevious IssuesPublished Ahead-of-Print Authors...

10.1097/pdm.0b013e3181601777 article EN Diagnostic Molecular Pathology 2008-11-19

Abstract The control of pre-analytical-factors in human biospecimens collected for health research is currently required. Only two previous reports using post-mortem brain samples have tried to address the impact cold-ischemia on tissue pH. Here we report pH variations according time (third-order polynomial model) mice liver, kidney and lung samples. Tissue alkalosis may be an underlying mechanism gene expression changes. Therefore, tissue-pH regulation after organ removal minimize biological stress

10.1038/s41598-017-11284-z article EN cc-by Scientific Reports 2017-09-01

Weanling male Wistar rats fed a choline-deficient diet develop acute kidney injury. Menhaden oil, which is very important source of omega-3 fatty acids, has notorious protective effect. The mechanism this protection unknown; one possibility could be that menhaden oil changes renal lipid profile, with an impact on the functions biological membranes. aim work was to study profile in or vegetable as lipids. Rats were divided into 4 groups and four different diets for 7 days:...

10.5650/jos.ess14186 article EN Journal of Oleo Science 2015-01-01

Fil: Moretti, L.. Centro de Educaciones Medicas e Investigacion Clinica Norberto Quirno; Argentina

10.9734/bjmmr/2014/3180 article IT British Journal of Medicine and Medical Research 2014-01-10

ObjectiveGuided Bone Regeneration (GBR) is a dental surgical procedure that uses barrier membranes to prevent soft tissue invasion and conduct new bone growth. This study aimed define Prognosis Recovery score (PR score) objectively classify post-surgery responders from non-responder patients who underwent GBR using Cone Beam Computed Tomography (CBCT).MethodsThis prospective-observational-longitudinal-cohort recruited 250 individuals were assigned to: Conventional-Apical-Surgery (CAS, n =...

10.1016/j.heliyon.2024.e33033 article EN cc-by-nc Heliyon 2024-06-01
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