A5006854732- Essential Oils and Antimicrobial Activity
- Natural Antidiabetic Agents Studies
- Phytochemicals and Antioxidant Activities
- Aldose Reductase and Taurine
- Research on Leishmaniasis Studies
- Venomous Animal Envenomation and Studies
- Pharmacological Effects of Medicinal Plants
- Inflammatory Bowel Disease
- Hydrogen's biological and therapeutic effects
- Nicotinic Acetylcholine Receptors Study
- Ion channel regulation and function
- Botanical Research and Applications
- Microplastics and Plastic Pollution
- Moringa oleifera research and applications
- Pharmacology and Obesity Treatment
- Synthesis of Organic Compounds
- Genomics, phytochemicals, and oxidative stress
- Ethnobotanical and Medicinal Plants Studies
- Microbial bioremediation and biosurfactants
- Pregnancy and Medication Impact
- Corrosion Behavior and Inhibition
- Drug Transport and Resistance Mechanisms
- Paraoxonase enzyme and polymorphisms
- Phytochemistry and Biological Activities
- Cultural Heritage Materials Analysis
University of Hassan II Casablanca
2020-2025
Hôpital Paul-Brousse
2024-2025
Inserm
2024-2025
Background: The search for new antifungal agents is critical due to the rising resistance of fungal pathogens existing treatments. This study focuses on synthesis and evaluation a novel compound, 1-benzyl-5-methyl-1H-pyrazole-3-carboxylic acid (compound L1), as potential agent. Methods: Compound L1 was synthesized characterized using range analytical techniques, including 1H^1H1H NMR, 13C^{13}C13C FT-IR, GC-MS, X-ray single crystal diffraction (XRD). activity compound assessed in vitro, its...
Leishmaniasis, caused by the Leishmania parasite, is a neglected public health issue. mainly infects macrophages, where metabolic reprogramming shapes their plasticity (M1/M2), affecting host’s resistance or susceptibility to infection. The development of this infection influenced immune responses, with an excessive anti-inflammatory reaction linked negative outcomes through modulation various mediators. Itaconate, produced Acod1 gene, recognized for its effects, but function in...
Abstract Type 1 diabetes is characterized by insulin deficiency due to the destruction of pancreatic β cells, leading hyperglycemia, which in turn induces vascular complications. In current study, we investigated effect intraperitoneal administration clove essential oil (CEO: 20 mg/kg body weight) on certain oxidative stress and glucose metabolism enzymes, as well expression proinflammatory mediators. Administration CEO diabetic rats showed a significant decline blood levels, total...
Inflammatory Bowel Disease-Associated Arthritis (IBD-associated arthritis) poses a significant challenge, intertwining the complexities of both inflammatory bowel disease (IBD) and arthritis, significantly compromising patient quality life. While existing medications offer relief, these drugs often initiate adverse effects, necessitating requirement for safer therapeutic alternatives.
Response surface methodology (RSM) with a Box-Behnken design (BBD) was used to optimize the extraction of bioactive compounds from Ephedra fragilis. The results suggested that 61.93% ethanol at 44.43 °C for 15.84 h best solution this combination variables. crude extract (CEE) obtained under optimum conditions sequentially fractionated solvents increasing polarity. content total phenolic (TP) and flavonoid (TF) as well antioxidant antiglycation activities were measured. phytochemical...
Origanum vulgare L. is an aromatic plant well-known in traditional medicine and widely applied as a food additive due to its great antimicrobial potential. This study aims investigate the chemical composition of essential oil (EO) O. using gas chromatography/mass spectroscopy (GC/MS) evaluate their antioxidant antibacterial activities against three strains Salmonella from avian origin. The EO was extracted by hydrodistillation Clevenger apparatus different compounds were identified GC/MS....
Lavandula mairei is an aromatic, and medicinal plant endemic to Morocco, mainly found in the southeastern region of Kingdom, used traditional medicine for its many benefits. The purpose study was identify chemical composition essential oil using Gas Chromatography - Tandem Mass Spectrometry, evaluate antimicrobial activity against bacterial strains (Staphylococcus aureus, Staphylococcus aureus MRSA, Enterococcus faecalis, Escherichia coli ATCC 25922, coli, Klebsiella pneumoniae 700603), two...
Abstract This study determined the chemical composition of Cinnamomum verum J.Presl, Cistus ladaniferus L., Laurus nobilis L. , Senecio anteuphorbuim, Boswellia serrata Roxb. ex Colebr. and Schinus molle essential oils (EOs) by gas chromatography‐mass spectrometry. Moreover, six EOs were screened in order to reveal their antibacterial antioxidant activities. They initially tested against pathogenic bacteria: Staphylococcus aureus (MRSA: methicillin‐resistant ), Escherichia coli (ESBL:...