A5040648187- Lung Cancer Treatments and Mutations
- Chronic Lymphocytic Leukemia Research
- Colorectal Cancer Treatments and Studies
- Multiple Myeloma Research and Treatments
- Pancreatic and Hepatic Oncology Research
- Lung Cancer Diagnosis and Treatment
- Renal cell carcinoma treatment
- Transplantation: Methods and Outcomes
- Acute Lymphoblastic Leukemia research
- Renal Diseases and Glomerulopathies
- Chemotherapy-related skin toxicity
- Ferroptosis and cancer prognosis
- Inflammatory Biomarkers in Disease Prognosis
- Gastrointestinal Tumor Research and Treatment
- CNS Lymphoma Diagnosis and Treatment
- Cancer Cells and Metastasis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Digestive system and related health
- Hematological disorders and diagnostics
- Metastasis and carcinoma case studies
- Neutropenia and Cancer Infections
- Management of metastatic bone disease
- Cancer-related cognitive impairment studies
- Gastric Cancer Management and Outcomes
Instituto Português de Oncologia de Coimbra Francisco Gentil
2024-2025
Hospital Pedro Hispano
2000-2021
This case report describes the clinical course, diagnosis, and management of a premenopausal woman with history estrogen receptor (ER)-positive human epidermal growth factor 2 (HER2)-positive early breast cancer (EBC) who developed severe thrombocytopenia. After six years diagnosis EBC (treated curative intent), she presented back pain, significant bruising, menorrhagia. During work-up, laboratory tests revealed thrombocytopenia, imaging studies, including computed tomography scan bone...
At diagnosis, approximately 50% of cases adenocarcinoma the pancreas are metastasized and 5-year survival is only 2.9%. We reported a case 63-year-old woman with pancreatic multiple hepatic intra-abdominal metastases that progressed on 2 lines chemotherapy. She has been under treatment third-line chemotherapy for 19 months stable disease excellent performance status. an overall 29 months. There just few metastatic long described in literature. The functional status good tolerance to may be...
<ns4:p>Background Breast cancer frequently leads to reduced work capacity and increased absenteeism among working-age women diagnosed with this condition. In study, we aimed assess the effect of CDK4/6i combined aromatase inhibitors (AIs) or fulvestrant on quality life (QoL) activity in a cohort Portuguese patients hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) metastatic breast who started treatment regimen. Methods This unicentric prospective...
Background: Lung cancer has a high incidence in elderly patients. These patients are more predisposed to therapeutic toxicities, drug interactions and limitations due physiologic alterations comorbidities. The use of single-agent versus combination chemotherapy (ChT) as first line treatment this group continues be debated. objective study is characterise diagnosed with lung at our institution evaluate overall survival (OS) population. Methods: This was retrospective multidisciplinary...
A 63-year-old man presented to the emergency department with acute confusion and a 1-month history of frequent falls. Neurological examination revealed anisocoria, unresponsiveness light stimulation ophthalmoplegia in right eye. Brain computed tomography (CT) demonstrated mass at cranial base (Figure 1). Additionally, brain magnetic resonance imaging (MRI) an extensive infiltrative lesion, centered on clivus 2). biopsy left nasal fossa showed neoplasm consisting relatively small cells,...
Nonspecific idiopathic interstitial pneumonias (NSIP), commonly described as pneumonitis, have an extensive differential diagnosis. The introduction of new drugs to treat chronic lymphocytic leukemia (CLL) improved the therapeutic arsenal and prognosis. Idelalisib has been shown be effective in controlling CLL. An acute onset cough, dyspnoea, fever are pneumonitis main manifestations, establishing a diagnosis with viral bacterial respiratory infections [1-3]. A 67-year-old woman history CLL...
Abstract Multiple myeloma (MM) frequently affects kidney function through multiple mechanisms. Nonetheless, some patients develop injury due to other causes. A 54-year-old woman was diagnosed with IgG kappa MM developed IgA nephropathy without cast nephropathy. Further studies did not show criteria for progression or This case highlights the need further investigation of in (such as toxicity previous drugs, infectious events, immune-mediated disorders).
Abstract Background: Multiple primary cancers in patients with head and neck squamous cell carcinoma (HNSCC) oesophageal (ESCC) share common features. Their treatment approach can be a challenge. This retrospective study aims to estimate the cumulative incidence describe outcome of multiple cancers, treated Tertiary Centre Portugal. Methods: The includes HNSCC, ESCC, tumours (synchronous or metachronous), curative intent Centre, between 2004 2019. analysis is focused on clinical baseline...