- Birth, Development, and Health
- Nutritional Studies and Diet
- Renin-Angiotensin System Studies
- Human Health and Disease
- Hormonal Regulation and Hypertension
- Ovarian cancer diagnosis and treatment
- Blood Pressure and Hypertension Studies
- Cardiac Valve Diseases and Treatments
- Pituitary Gland Disorders and Treatments
- Apelin-related biomedical research
- Natural Antidiabetic Agents Studies
- Cardiac Arrhythmias and Treatments
- Cancer Diagnosis and Treatment
- Air Quality and Health Impacts
- Cancer and Skin Lesions
- Pharmaceutical Practices and Patient Outcomes
- Renal and Vascular Pathologies
- Cardiac Imaging and Diagnostics
- COVID-19 Clinical Research Studies
- Healthcare Systems and Public Health
- Menopause: Health Impacts and Treatments
- Neuroendocrine regulation and behavior
- Maternal Mental Health During Pregnancy and Postpartum
- Thermoregulation and physiological responses
- Cerebrovascular and Carotid Artery Diseases
Grigore T. Popa University of Medicine and Pharmacy
2014-2024
Clinical Emergency Hospital Bucharest
2021
Iuliu Hațieganu University of Medicine and Pharmacy
2020
Lucian Blaga University of Sibiu
2019
Spitalul Clinic Judeţean de Urgenţe "Sf. Spiridon" Iaşi
2019
Spitalul Clinic C.F. Iasi
2013-2019
ImmunoGen (United States)
2019
Hai phong University Of Medicine and Pharmacy
2019
Mental Health Research Institute
2013
The University of Melbourne
2009-2011
It has been known for almost a decade and half that in trypanosomes all mRNAs are trans-spliced by addition to the 5′ end of spliced leader (SL) sequence. During same time period conviction developed classical cis-splicing introns not present trypanosome genome gene arrangement is highly compact with small intergenic regions separating one from next. We have now discovered these tenets no longer true. Poly(A) polymerase (PAP) genes Trypanosoma brucei cruzi split intervening sequences 653 302...
The pattern of regional brain activation in humans during thirst associated with dehydration, increased blood osmolality, and decreased volume is not known. Furthermore, there little information available about associations between osmoreceptive regions such as the organum vasculosum lamina terminalis implicated its satiation humans. With objective investigating neuroanatomical correlates dehydration ventral terminalis, this study involved exercise-induced sweating 15 people measures...
This study aims to investigate the effects of testosterone on cognitive performance during functional magnetic resonance imaging (fMRI) in healthy estrogen-treated postmenopausal women.This was an open-label which women nonoral estrogen therapy were treated with transdermal for 26 weeks. Women performed tests verbal fluency (number words) and mental rotation (reaction time accuracy) pretreatment posttreatment fMRI. Blood oxygen level-dependent (BOLD) signal intensity measured fMRI tasks.Nine...
The roots of Vernonia kotschyana Sch. Bip. ex Walp. (Asteraceae) are used in Malian traditional medicine the treatment gastroduodenal ulcers and gastritis. Since oxidative stress is involved gastric ulceration, aim this study was to screen root extracts for their vitro antioxidant activity phenolic content. were extracted successively with chloroform, ethyl acetate, ethanol water. evaluated both cell-free cell-based assays. Their chemical characterization performed by Fourier transform...
Background and objectives: This study assesses electronic cigarette (e-cigarette) use its relationship with smoking alcohol illicit drug consumption among Romanian university students. Materials methods: A cross sectional using anonymous questionnaire was performed in 2017 400 students from Cluj-Napoca, Romania. Results: 95.5% of the participants had heard about e-cigarettes 43.7% these tried during their lifetime, while 8.9% declared cigarettes previous month (one out five who them...
Tobacco consumption is the most incriminated and studied risk factor for Chronic obstructive pulmonary disease (COPD), but other factors such as air pollution, are also linked to this disease. One of known aspects chronic lung that its occurrence mainly due inflammation airways. Lipid metabolism seems be affected by smoking, with studies showing a correlation between habit high levels triglycerides low high-density lipoprotein cholesterol (HDL-CHOL). Uric acid concentration thought reflect...
Environmental concerns have consistently been a focal point for the scientific community. Pollution is critical ecological issue that poses significant threats to human health and agricultural production. Contamination with heavy metals pesticides considerable concern, threat environment, warrants special attention. In this study, we investigated issues arising from sub-chronic exposure imidacloprid (IMI), mercury (Hg), cadmium (Cd), either alone or in combination, using zebrafish (
Maintaining the soil in optimal parameters is vital for mankind, given its essential role providing alimentary base, as well extremely slow formation and regeneration (hundreds or thousands of years). The direct indirect pollution especially chemical represent a corollary other types pollution, that it produced by solid, liquid gaseous residues. It may be involved wide range diseases (respiratory, cardiovascular, digestive, renal, haematological, osteoarticular, neurological) allergic,...
Introduction: Risk factors for cerebrovascular disease (CVD) are nonmodifiable and modifiable. Non-modifiable represented by: age, family history of CVD, race, sex, stroke or transient ischemic attack, the following considered modifiable factors: diet rich in fat salt, sedentary lifestyle, obesity, smoking, hypertension, diabetes mellitus, hypercholesterolemia, arterial disease, peripheral artery atrial fibrillation sickle cell disease. It appears that most involved occurrence with some...
Aim of the study. The permanent exchanges between body and environment tend to generally disturb homeostasis, particularly hydroelectrolytic homeostasis. analysis renin-angiotensin system reveals its multiple facets physiological, physiopathological pharmacological interest at same time highlights fact that it represents a major component biomedical scientific research. Material methods. We studied action on utero-tubal motility with help certain substances affect metabolism affinity...
The aim of this study was to evaluate the effect renin- angiotensin- aldosterone system on blood pressure from a hormonal perspective. Additionally, correlation between cardiovascular pathology and mechanisms examined. Material methods. A comprehensive literature search conducted using databases such as PubMed, MEDLINE, Cochrane Library, focusing studies related in hypertension angiotensin -aldosterone system. Data extraction quality assessment were performed relevant peer-reviewed articles,...
Given the structural resemblances between glass fiber and asbestos, it is important to understand mechanisms through which exposure fibers may affect respiratory system. To study effect of on rat lung intratracheal exposure, considering subject�s weight variation, together with haematological parameters, C-reactive protein (CRP), total number lymphocytes, IL8 concentration in bronchoalveolar lavage. We performed an instillation four groups 8 randomly selected Wistar rats, by administering 3...
Lung and airway involvement in inflammatory bowel disease are increasingly frequently reported either as an extraintestinal manifestation or adverse effect of therapy.We report a case patient with ulcerative colitis controlled under mesalazine treatment who presented chronic cough hemoptysis. Chest computed tomography bronchoscopy findings supported tracheal colitis; pathology examination demonstrated unusual eosinophil-rich pattern, together clinical data, nonasthmatic eosinophilic...
Although thiazide-like diuretics were initially known to have little or no metabolic side-effects, some later evidence showed of their adverse reactions.We aimed survey side-effects in long term administration.We conducted a prospective pharmacovigilance study on the indapamide V th Internal Medicine Clinic Iași, Romania, between 2016 and 2018.Thirty hypertensive patients monitored regarding glycaemia, uricemia kaliemia before starting administration (T0), after at least three months (T1)...