Palliative care is a challenging specialty, especially when it comes to caring for children with serious life-limiting conditions and supporting their families. Workers face significant challenges experience major impacts on wellbeing. We conducted qualitative study understand the sources of stress in palliative team, work expectations, how they can cope demands.

Background: In the context of modern oncology, radiogenic elements have emerged as pivotal tools for targeted cancer therapies. Elements like Iodine-131 and Yttrium-90 offer unique radiological properties that allow precise treatment delivery. This article explores their growing importance potential in reshaping landscape therapy. Methods: Utilizing a systematic literature search, relevant studies, clinical trials, research articles were collected from databases. The selected material was...

Background: Respiratory infections pose a significant public health challenge, particularly among healthcare workers (HCWs). The COVID-19 pandemic exacerbated absenteeism due to respiratory illnesses, affecting workforce stability. Identifying factors influencing is crucial for resilience and effective care. Methods: This retrospective longitudinal study analyzed HCW diseases from 2017 2023 at the "Sf. Maria" Children's Emergency Hospital in Iași, Romania. Data 3827 HCWs were examined,...

<p dir="ltr"><span>Motherhood involves profound hormonal, physical, and psychological transformations, along with shifts in social status, daily routines, sleep patterns, all of which can impact the mother-child relationship increase maternal vulnerability. These challenges are particularly pronounced adolescent mothers, who may experience heightened emotional distress, inadequate family support, or rejection, complicating their breastfeeding journey. Despite targeted health...

Introduction: Increasingly, SGLT2 inhibitors save patients with heart failure and comorbidities such as type-2 diabetes mellitus (T2DM) chronic kidney disease (CKD); the inhibition of sodium-glucose cotransporter 2 (SGLT2) was first studied in a solution to lower glucose levels by preventing reabsorption facilitating its elimination; process, researchers took notice how also seemed have beneficial cardiovascular effects both disease. Aim: Our single-center prospective study assesses outcomes...

Background: In children’s palliative care, the term “respite” refers to a temporary break offered primary caregivers of child with life-limiting illness. The aim this study was assess perceptions parents who have benefited from respite care services in Lumina Association, Bacău hospice unit and benefits it can bring improving their psycho-emotional state. Methods: consisted quantitative research involving 34 parents/caregivers responded questionnaire 26 questions, qualitative which involved...

Abstract: Lumbar disc herniation is a degenerative neurological disorder characterized by notable rise in incidence and prevalence among the population modern times. It primarily caused factors such as microtrauma, sedentary lifestyle, prolonged static postures, excessive time spent at computer, overexertion. Materials methods: A study was conducted retrospectively from 2022 to 2023 on patients who were admitted with lumbar herniation, Neurosurgery Hospital "Prof. N. Oblu”, Iași.The research...

Over the past two decades, resistance to antibiotics, especially for Gram-negative bacteria, has increased at an alarming rate, requiring constant concern resolving and controlling this extremely important therapeutic aspect in any medical department but particular, Anaesthesia Intensive Care Units, units of neonatology, paediatrics, neurosurgery, burned patients immunosuppressed. Specialists note a particular Enterobacteriaceae third-generation cephalosporins aztreonam, with profile...

From their discovery, antibiotics have significantly improved clinical treatments of infections, thus leading to diminishing morbidity and mortality in critical care patients, as well surgical, transplant other types medical procedures. In contemporary medicine, a significant debate regarding the development multi-drug resistance involves all pathogens, especially acute hospitals due suboptimal or inappropriate therapy. The possibility nanotechnology using nanoparticles matrices encapsulate...

Recently, nanotechnology research studies have been proven that use of various nanoparticles as drug delivery systems to target and annihilate pathogenic microorganisms may be a good solution for prevention treatment severe infection. In the last few years, antimicrobial encapsulation into nano-sized has materialized promising alternative increased efficacy minimized adverse effects. Physicochemical properties erythromycin-loaded polymer were assessed using particle size distribution, HPLC,...

Modern medicine has a vast set of antibiotics frequently prescribed in therapeutic practice. Beta-lactam are often indicated prophylaxis and treatment bacterial infections caused by susceptible microorganisms. This work concerned on analysis antibiotic structure influence resistance knowing that wide variety bacteria developed different mechanism make resistant to some or nearly all antibiotics. The emergence antibiotic-resistant pathogens is relevant area study medical Furthermore,...

Irritable bowel syndrome (IBS) is not a disease. It group of symptoms that occur together, as: chronic or recurrent abdominal pain, altered habits, and bloating, with the absence structural biochemical abnormalities. functional gastrointestinal disorder. The causes IBS are poorly understood. Limited information available about number children IBS. affects boys girls equally, but each person differently. can be very difficult to diagnose. diagnosed by exclusion. To diagnose IBS, health care...

Some infectious agents frequently act on human body. Multi-drug resistant microorganisms (MDR) develop the capacity to stabilize biofilms. The use of antimicrobials loaded nanoparticles can defeat antibiotic resistance mechanism. major aim this study was synthesis and physico-chemical characterization Colistin molecules intercalated in order enhance efficacy against multi-drug microorganisms. Advanced techniques were used analyze new nanostructures containing antibiotics improve...

Nowadays, infection diseases are one of the most significant threats to humans all around world. An encouraging strategy for solving this issue and fighting resistant microorganisms is develop drug carriers a prolonged release antibiotic target site. The purpose work was obtain metronidazole-encapsulated chitosan nanoparticles using an ion gelation route evaluate their properties. Due advantages ionic method, synthesized polymeric can be applied in various fields, especially pharmaceutical...

The development of antibiotic resistance in bacteria possesses a huge threat to public health by nullifying the effect even most efficient antibiotics. From years, LDHs type nanomaterials have been used as drug carriers for wide variety pharmaceutically active molecules due their delivery properties, making these inorganic-organic nanohybrids very antimicrobial agents. major purpose this work was synthesize and characterize ceftriaxone intercalated layered nanostructures further use treat...

Maintaining the soil in optimal parameters is vital for mankind, given its essential role providing alimentary base, as well extremely slow formation and regeneration (hundreds or thousands of years). The direct indirect pollution especially chemical represent a corollary other types pollution, that it produced by solid, liquid gaseous residues. It may be involved wide range diseases (respiratory, cardiovascular, digestive, renal, haematological, osteoarticular, neurological) allergic,...

A major public health threat that affects humans is recognized worldwide as an occurrence of antibiotic resistance regarding bacterial pathogen. Multidrug resistant microorganisms appeared in the hospitals and community settings respectively insinuating antibiotic-resistant bacteria are present even outside hospital environment. First stage adaptation top evolution represented by response to drug assault. Then, survival fittest a consequence biochemical genetically alteration. Therefore,...

Novel materials belonging to the class of anionic clays are synthesized by investigating their properties at nano scale. Thus, hydrotalcites or layered double hydroxides (LDHs) were used as drug delivery carriers in order prevent treat infections produced some pathogen agents. Their physical and chemical allow them include different molecules interlayer space then ensure transport target. The current work reveals obtaining nanohybrid compounds type amoxicillin/clavulanic acid-layered...

The usual treatment for tuberculosis is difficult by its long-term therapy, raised dosing frequency and adverse effects of anti-tuberculosis drugs. Anionic clays, also called layered double hydroxides are a class hydrotalcite like structures having high compositional variety being able to self-assembly in the presence drug molecules. work refers development nanohybrid materials delivery systems that intercalates isonicotinic acid hydrazide, known as isoniazid drug, into structure compounds....

Carbapenem antibiotics resistance is a medical threat in antibacterial therapy as the pathogen resistant strains easily evolve multi-drug action to other incurable agents. The protective transport of current antibiotic molecules using nano-carriers initiates huge approach therapy, allowing nanohybrids defeat all these health Chitosan linear cationic polysaccharide being often used area biocompatible encapsulating agent delivery nanosystems. This work refers encapsulation imipenem into...

Nowadays bone implant removal is caused by infection that occurs around it possibly acquired after surgery or during hospitalization. The purpose of this study was to reveal some metal oxides applied as coatings on thus limiting the usual antibiotics-resistant bacteria colonization. Therefore ZnO, TiO2 and CuO were synthesized structurally morphologically analized in order use them an alternative antimicrobial agents deposited implant. XRD, SEM, FTIR characterization techniques used identify...

Abstract Introduction The COVID-19 pandemic, with massive absenteeism from work due to sickness and quarantine, has put pressure on healthcare workers. Our study compared staff illness patterns in a pediatric emergency clinical university hospital during the pandemic pre-pandemic years. Methods A retrospective analysis of temporary incapacity was carried out using medical leaves data 2017-2019 2020-2022. Results sick 1217 employees were classified by disease groups. Between 2017 2022, number...

Abstract Introduction Cardiac complications of SARS-CoV-2 infection have had a significant impact on quality life and work in affected individuals. COVID-19 vaccines reduced case fatality, but side effects been reported. Methods We present the physician with history arrhythmogenic cardiomyopathy following viral myocarditis. After administration first dose COVID 19 mRNA vaccine, she presented suggestive symptoms for acute heart failure. In absence any other diagnostic evidence to explain...