Palliative care is a challenging specialty, especially when it comes to caring for children with serious life-limiting conditions and supporting their families. Workers face significant challenges experience major impacts on wellbeing. We conducted qualitative study understand the sources of stress in palliative team, work expectations, how they can cope demands.

Cardiovascular diseases (CVD) remain the leading cause of global mortality, with Romania classifiedas a high cardiovascular risk country. Sedentary behaviors and obesity, closely interrelated factors,significantly contribute to increased CVD risk. This study analyzed 45 subjects aged between 18and 49 years, none them being professional athlete. Data collected included sex, age, BMI,metabolic equivalents (METs), predictive values for age sex patient. The aimedto evaluate relationship these...

This case study describes the evolution of a 45-year-old patient who presented to hospital with severe inferior respiratory tract infection. The interpretation electrocardiogram led reconsideration medical history and identification anginal pain, resulting in referral cardiology department. investigations carried out (biochemical tests, stress test, coronary angiography) established diagnosis angina non-obstructive arteries (ANOCA). uniqueness lies association this combination traditional...

Background: In the context of modern oncology, radiogenic elements have emerged as pivotal tools for targeted cancer therapies. Elements like Iodine-131 and Yttrium-90 offer unique radiological properties that allow precise treatment delivery. This article explores their growing importance potential in reshaping landscape therapy. Methods: Utilizing a systematic literature search, relevant studies, clinical trials, research articles were collected from databases. The selected material was...

Background and Objectives: Cardiac involvement in COVID-19 has been confirmed during the acute stage of infection. However, prevalence spectrum post-infectious cardiac dysfunction remain incompletely clarified. The objective our study was to evaluate frequency echocardiographic changes 2 years after hospitalization for moderate severe patients with no previously known pathology. Material Methods: We conducted a retrospective cohort analyzing severity markers infection parameters assessed ≥2...

(1) Context: Cancer is still a major problem worldwide, and traditional therapies like radiation chemotherapy often fail to alleviate symptoms because of side effects, systemic toxicity, mechanisms resistance. Beneficial anticancer effects that spare healthy tissues are made possible by the distinctive redox characteristics noble metal complexes, especially those containing palladium, gold, silver, platinum. (2) Methods: The processes, molecular targets, therapeutic uses complexes in cancer...

Atherosclerotic cardiovascular disease (ASCVD) has been screened for decades using the traditional lipid profile, with by far most emphasis on low-density lipoprotein-cholesterol (LDL). Even though more recent studies have suggested that there might be to atherosclerosis than LDL, inflammation and immune processes being some of possible culprits, solid recommendations still haven’t made regarding potential use other biomarkers. Most research focused Lipoprotein(a) [Lp(a)], an independent...

Clinical manifestations and mortality caused by SARS-CoV-2 change, consistent with circulating viral variants population immunity. Our retrospective study analyses the hospitalized COVID-19 cases from Romania in 2024 comparative 2020. The circulation of fourth year pandemic led to changes characteristics population, including clinical, biological, radiological profiles, as well an increase 90-day after hospitalization. became predominantly older multiple comorbidities. Notable symptomatology...

Inhaler therapy plays a crucial role in controlling respiratory symptoms patients with chronic obstructive pulmonary disease (COPD). Incorrect or partially correct use of inhaler devices causes many (COPD) to continue have due poor drug deposition the airways as result technique, leading increased healthcare costs exacerbations and multiple emergency room presentations. Choosing right device for each individual patient is bigger challenge doctors patients. The type technique depends on...

Introduction: Increasingly, SGLT2 inhibitors save patients with heart failure and comorbidities such as type-2 diabetes mellitus (T2DM) chronic kidney disease (CKD); the inhibition of sodium-glucose cotransporter 2 (SGLT2) was first studied in a solution to lower glucose levels by preventing reabsorption facilitating its elimination; process, researchers took notice how also seemed have beneficial cardiovascular effects both disease. Aim: Our single-center prospective study assesses outcomes...

Background: In children’s palliative care, the term “respite” refers to a temporary break offered primary caregivers of child with life-limiting illness. The aim this study was assess perceptions parents who have benefited from respite care services in Lumina Association, Bacău hospice unit and benefits it can bring improving their psycho-emotional state. Methods: consisted quantitative research involving 34 parents/caregivers responded questionnaire 26 questions, qualitative which involved...

Abstract: Lumbar disc herniation is a degenerative neurological disorder characterized by notable rise in incidence and prevalence among the population modern times. It primarily caused factors such as microtrauma, sedentary lifestyle, prolonged static postures, excessive time spent at computer, overexertion. Materials methods: A study was conducted retrospectively from 2022 to 2023 on patients who were admitted with lumbar herniation, Neurosurgery Hospital "Prof. N. Oblu”, Iași.The research...

This review aims to evaluate efficacy and drug treatment options in cases of vaginal vulvar candidiasis associated with diabetes. We conducted an exhaustive literature review, looking at relevant clinical trials, meta-analyses, experiences. Patients diabetes mellitus were included a case study assess their response treatment. Antifungals such as fluconazole clotrimazole have been effective treating candidiasis, but success has influenced by glucose control levels. Proper management, along...

From their discovery, antibiotics have significantly improved clinical treatments of infections, thus leading to diminishing morbidity and mortality in critical care patients, as well surgical, transplant other types medical procedures. In contemporary medicine, a significant debate regarding the development multi-drug resistance involves all pathogens, especially acute hospitals due suboptimal or inappropriate therapy. The possibility nanotechnology using nanoparticles matrices encapsulate...

Recently, nanotechnology research studies have been proven that use of various nanoparticles as drug delivery systems to target and annihilate pathogenic microorganisms may be a good solution for prevention treatment severe infection. In the last few years, antimicrobial encapsulation into nano-sized has materialized promising alternative increased efficacy minimized adverse effects. Physicochemical properties erythromycin-loaded polymer were assessed using particle size distribution, HPLC,...

Nowadays, infection diseases are one of the most significant threats to humans all around world. An encouraging strategy for solving this issue and fighting resistant microorganisms is develop drug carriers a prolonged release antibiotic target site. The purpose work was obtain metronidazole-encapsulated chitosan nanoparticles using an ion gelation route evaluate their properties. Due advantages ionic method, synthesized polymeric can be applied in various fields, especially pharmaceutical...

Aorto-atrial fistula (AAF) and aorto-ventricular (AVF) are a rare, but potentially life-threatening condition, where an anomalous connection forms between the aortic structures cardiac atria or ventricles. The exact incidence of this condition is unknown, as major precipitating factors best treatment options. It may be congenital, secondary to conditions such dissection, infective endocarditis, valve replacement, iatrogenic in nature. In case reported here 72-year-old male who was found have...

Temporomandibular disorders (TMD) are multisymptomatic conditions, with a frequency of 11-31% in the general population, that can lead over time to irreversible structural changes temporomandibular joint (TMJ). Juvenile idiopathic arthritis (JIA) is most common inflammatory autoimmune disorder involvement childhood and implicated genesis dysfunction. Material Methods. A prospective clinical-epidemiologic study was carried out period 2022-2023 Children's Emergency Clinical Hospital "Sf....

Aim of the study. Recent studies have shown that medical errors are an increasingly common cause patient morbidity and mortality. For this reason, there several approaches to identifying their causes. These include but not limited retrospective reporting, error analysis, or forward-looking analysis identify high-risk situations. In context, research aims analyse a series sources methods contribute qualitative assessment data used in safety risk analysis. Results. The results our study show...

Microbial resistance is a rapidly escalating phenomenon worldwide, with complex mechanisms and important involvement in the determinants of healthcare-associated in-hospital infections. At European level, it estimated that 80.000 hospitalised patients have at least one HAI every day multi-antimicrobial resistant germs, leading to an extension hospital stay by 16 million days year. In high-income countries, prevalence around 7.5%, low- middle-income ranges from 5.7% 19.2%. Material method....