A5109449034- Bone fractures and treatments
- Spine and Intervertebral Disc Pathology
- Nanocomposite Films for Food Packaging
- Advanced Drug Delivery Systems
- Material Properties and Applications
- Plant Pathogenic Bacteria Studies
- Total Knee Arthroplasty Outcomes
- Advanced Photocatalysis Techniques
- Long-Term Effects of COVID-19
- Biofield Effects and Biophysics
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Nanomaterials for catalytic reactions
- Microbial Community Ecology and Physiology
- biodegradable polymer synthesis and properties
- Pulmonary Hypertension Research and Treatments
- Layered Double Hydroxides Synthesis and Applications
- Musculoskeletal pain and rehabilitation
- Polymer Surface Interaction Studies
- Antibiotic Use and Resistance
- Antimicrobial agents and applications
- Microbial Metabolites in Food Biotechnology
- Magnetic and Electromagnetic Effects
- Meat and Animal Product Quality
- Hip and Femur Fractures
Apollonia University
2020-2024
Clinica de Pneumologie Iaşi
2020-2023
Lomonosov Moscow State University
2005
Background Radiation therapy, integral to pelvic tumor management, impacts over half of all cancer patients and may lead anal sphincter dysfunction due inflammatory responses chronic fibrotic remodeling in irradiated tissues. To address this, a targeted animal model has been developed investigate early post-radiotherapy toxicity evaluates the efficacy anti-fibrotic anti-inflammatory agents, Pirfenidone Meloxicam, as potential treatments against radiotherapy-induced dysfunction. Methods...
Abstract: Lumbar disc herniation is a degenerative neurological disorder characterized by notable rise in incidence and prevalence among the population modern times. It primarily caused factors such as microtrauma, sedentary lifestyle, prolonged static postures, excessive time spent at computer, overexertion. Materials methods: A study was conducted retrospectively from 2022 to 2023 on patients who were admitted with lumbar herniation, Neurosurgery Hospital "Prof. N. Oblu”, Iași.The research...
From their discovery, antibiotics have significantly improved clinical treatments of infections, thus leading to diminishing morbidity and mortality in critical care patients, as well surgical, transplant other types medical procedures. In contemporary medicine, a significant debate regarding the development multi-drug resistance involves all pathogens, especially acute hospitals due suboptimal or inappropriate therapy. The possibility nanotechnology using nanoparticles matrices encapsulate...
Recently, nanotechnology research studies have been proven that use of various nanoparticles as drug delivery systems to target and annihilate pathogenic microorganisms may be a good solution for prevention treatment severe infection. In the last few years, antimicrobial encapsulation into nano-sized has materialized promising alternative increased efficacy minimized adverse effects. Physicochemical properties erythromycin-loaded polymer were assessed using particle size distribution, HPLC,...
The aim of the paper is to identify optimal plastic type used in obtaining thoraco-lumbar orthoses - treatments comminutive fracture, burst fracture vertebrae lumbar area. For this purpose, with help Finite Element Analysis (FEA), a theoretical study was carried out on influence elastic properties plastics, achieving orthoses, state tension and local displacements bone fragments from traumatized area under condition movement base extension flexion. In force flexion, modulus material varied...
Nowadays, infection diseases are one of the most significant threats to humans all around world. An encouraging strategy for solving this issue and fighting resistant microorganisms is develop drug carriers a prolonged release antibiotic target site. The purpose work was obtain metronidazole-encapsulated chitosan nanoparticles using an ion gelation route evaluate their properties. Due advantages ionic method, synthesized polymeric can be applied in various fields, especially pharmaceutical...
Biomechanical efficacy is critical in managing tibial plateau fractures. This study compared the performance of polyaxial screw-plate implant systems under axial loading conditions using synthetic bone models. Osteosynthesis methods involving lateral, medial, and combined (lateral + medial) plates were evaluated. Although no statistically significant differences stiffness stability observed across all groups progressive loading, lateral medial plate technique demonstrated superior...
Microbial resistance is a rapidly escalating phenomenon worldwide, with complex mechanisms and important involvement in the determinants of healthcare-associated in-hospital infections. At European level, it estimated that 80.000 hospitalised patients have at least one HAI every day multi-antimicrobial resistant germs, leading to an extension hospital stay by 16 million days year. In high-income countries, prevalence around 7.5%, low- middle-income ranges from 5.7% 19.2%. Material method....
Pulmonary arterial hypertension is a disorder of high mortality being described by progressive increase in pulmonary vascular strength leading to right ventricular damage and death. Endotelin-1 (ET-1) has an important pathogenic fuction hypertension. Bosentan oral ET-1 receptor antagonist that proved be efficient at exercise tolerance patients with functional class III IV. The early trial registered for II evaluated hemodynamic 6 month. Considerable side effects bosentan comprise anemia,...
The fourth generation cephalosporin antibacterial agent, cefepime, was loaded into layered double hydroxides for enhancing antibiotic efficiency, reducing side effects, as well achieving the sustained release property. intercalation of inter-gallery ZnAl-layered hydroxide (LDH) carried out using ion exchange method, by this constituting a nano-sized organic-inorganic hybrid material controlled novel formulation. Although cefepime is broad spectrum antibiotic, it has various adverse effects...