Alin Iordache

ORCID: 0000-0002-3933-3393
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About
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Research Areas
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Traumatic Brain Injury Research
  • Psychosomatic Disorders and Their Treatments
  • Glioma Diagnosis and Treatment
  • Cerebrospinal fluid and hydrocephalus
  • Neurosurgical Procedures and Complications
  • Microbial infections and disease research
  • Advanced Drug Delivery Systems
  • Antibiotic Use and Resistance
  • Layered Double Hydroxides Synthesis and Applications
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Neurological disorders and treatments
  • Antibiotic Resistance in Bacteria
  • Liver Diseases and Immunity
  • Advanced Electron Microscopy Techniques and Applications
  • Paranormal Experiences and Beliefs
  • Poxvirus research and outbreaks
  • Transcranial Magnetic Stimulation Studies
  • Noise Effects and Management
  • Medicinal Plants and Neuroprotection
  • Viral Infections and Vectors
  • Liver Disease Diagnosis and Treatment
  • Acupuncture Treatment Research Studies
  • Antimicrobial agents and applications
  • Vascular Malformations Diagnosis and Treatment

Grigore T. Popa University of Medicine and Pharmacy
2014-2024

Clinical Emergency Hospital Bucharest
2021

Clinica de Pneumologie Iaşi
2019-2020

"Dunarea de Jos" University of Galati
2018

Engineering Science Analysis (United States)
2017

Amita Health St. Mary's Hospital
2014

Functional neurological disorder (FND), formerly called conversion disorder, is a condition characterized by symptoms that lack an identifiable organic purpose. These signs, which can consist of motor, sensory, or cognitive disturbances, are not deliberately produced and often vary in severity. Its diagnosis predicated on clinical evaluation the exclusion other medical psychiatric situations. treatment typically involves multidisciplinary technique addressing each underlying psychological...

10.3390/ijms25084470 article EN International Journal of Molecular Sciences 2024-04-18

<p dir="ltr"><span>Mild traumatic brain injury (mTBI) is a common public health problem that significantly affects millions of people, especially people in high-risk occupations. Post-concussive cognitive impairment (PCCI) prevalent and debilitating outcome mTBI has major impact on function as well quality life, thus affecting long-term outcomes. Of all injuries, accounts for 58-88%, according to epidemiological studies. However, sufferers report multitude emotional symptoms...

10.70594/brain/16.1/6 article EN BRAIN BROAD RESEARCH IN ARTIFICIAL INTELLIGENCE AND NEUROSCIENCE 2025-02-04

Over the past two decades, resistance to antibiotics, especially for Gram-negative bacteria, has increased at an alarming rate, requiring constant concern resolving and controlling this extremely important therapeutic aspect in any medical department but particular, Anaesthesia Intensive Care Units, units of neonatology, paediatrics, neurosurgery, burned patients immunosuppressed. Specialists note a particular Enterobacteriaceae third-generation cephalosporins aztreonam, with profile...

10.37358/rc.19.7.7392 article EN Revista de Chimie 2019-08-15

From their discovery, antibiotics have significantly improved clinical treatments of infections, thus leading to diminishing morbidity and mortality in critical care patients, as well surgical, transplant other types medical procedures. In contemporary medicine, a significant debate regarding the development multi-drug resistance involves all pathogens, especially acute hospitals due suboptimal or inappropriate therapy. The possibility nanotechnology using nanoparticles matrices encapsulate...

10.3390/ma13214792 article EN Materials 2020-10-27

Infantile hemangiomas (IHs) are the most frequent pediatric benign vascular tumors, with a reported incidence of 5% to 10%.They have self-limiting evolution pattern divided into growth phase in first 12 months and regression one, that may take up 10 years.Occasionally, might lead local or systemic complications, depending on their morphological characteristics.The line treatment is β-blockers, such as Propranolol, Timolol, Nadolol, administered either locally systemically.Newer therapeutic...

10.47162/rjme.61.3.07 article EN Romanian Journal of Morphology and Embryology 2021-04-01

About 1% of childhood tumors can be malignant ovarian and differential diagnosis with benign ones is sometimes difficult before surgery. Concerning the management such in adolescents for which future fertility a concern, there specific interest their potential possible use ovarian-sparing operative techniques, as well suitability chemotherapy. To exemplify difficulties preoperative diagnosis, personalized approach deciding to preserve affected ovary, we report rare case 14-year-old female...

10.2147/ijwh.s374444 article EN cc-by-nc International Journal of Women s Health 2022-08-01

Some infectious agents frequently act on human body. Multi-drug resistant microorganisms (MDR) develop the capacity to stabilize biofilms. The use of antimicrobials loaded nanoparticles can defeat antibiotic resistance mechanism. major aim this study was synthesis and physico-chemical characterization Colistin molecules intercalated in order enhance efficacy against multi-drug microorganisms. Advanced techniques were used analyze new nanostructures containing antibiotics improve...

10.37358/rc.19.10.7635 article EN cc-by Revista de Chimie 2019-11-15

Novel materials belonging to the class of anionic clays are synthesized by investigating their properties at nano scale. Thus, hydrotalcites or layered double hydroxides (LDHs) were used as drug delivery carriers in order prevent treat infections produced some pathogen agents. Their physical and chemical allow them include different molecules interlayer space then ensure transport target. The current work reveals obtaining nanohybrid compounds type amoxicillin/clavulanic acid-layered...

10.37358/mp.18.4.5072 article EN cc-by Materiale Plastice 2018-12-30

Cognitive decline is one of the most important challenges related to aging process, due its impact on individuals. Several studies have reported that physical exercise with a specific intensity and frequency beneficial for maintaining cognitive health in ageing population. The present study investigated general older population Romania. involved 60 individuals (60% male, 40% female), mean age 60.78 years (SD = 2.97). Health Interview Survey Minnesota Heart assessed intensity, while Montreal...

10.3390/healthcare12171791 article EN Healthcare 2024-09-07

<p>Mild Traumatic Brain Injury (mTBI) is a prevalent neurological condition that can lead to persistent cognitive impairments, disrupting memory, attention, and executive function. In this study, we explore the mechanisms of decline in mTBI through lens Markov blankets—a theoretical framework delineates statistical boundary between brain’s internal external states. By simulating impact on sensory, active, internal, states, demonstrate how disruptions blanket structure contribute...

10.70594/brain/15.3/1 article EN BRAIN BROAD RESEARCH IN ARTIFICIAL INTELLIGENCE AND NEUROSCIENCE 2024-10-12

Background: Medicinal plants like Guiera senegalensis J. F. Gmel. (GS) have gained attention for their potential neuroprotective effects due to rich composition of bioactive compounds, including flavonoids and polyphenolic acids. While previous studies highlighted the antioxidant, anti-inflammatory, neuroplasticity-enhancing properties GS extract, its efficacy in mitigating dementia-related pathology remains be fully understood. Objectives: This study aimed investigate hydroethanolic extract...

10.5812/jjnpp-147530 article EN Jundishapur Journal of Natural Pharmaceutical Products 2024-10-14

Context: Functional neurological disorder (FND) is common in neurology outpatient clinics, affecting approximately 6% of patients. characterized by motor and sensory symptoms that cannot be explained organic or structural issues. These often mimic those recognized conditions, making diagnosis treatment complex. Evidence Acquisition: This study presents a comprehensive voxel-wise meta-analysis brain changes FND to explore potential quantitative measurements could serve as biomarkers for...

10.5812/ijpbs-148266 article EN Iranian Journal of Psychiatry and Behavioral Sciences 2024-12-22

The correlation between the high incidence of oro-dental pathologies (periodontitis, oral cancer) and increased level ROS in human body have led to need use alternative treatments, namely active principles from medicinal plants that a considerable antioxidant effect, thus reducing risk producing these pathologies. In this sense, some bioactive compounds present such as turmeric acid extracted Curcuma longa, polyphenolic Camellia sinensis, apigenin Moringa oleifera, timolol Thymus vulgaris,...

10.62610/rjor.2024.2.16.28 article EN cc-by 2024-03-15

Background Patients with chronic neuropathic pain often report symptoms of depression. The aim this work is to determine the intensity and identify efficacy spinal neurostimulation in a group patients surgery Materials Methods: study includes 60 after surgery, who received cord implant between October 2017 January 2024, at Professor Nicolae Oblu Emergency Clinical Hospital, Iasi. Prior implant, patient was evaluated neurologically, psychologically, imaging, electromyography underwent...

10.62610/rjor.2024.3.16.16 article EN cc-by 2024-09-15

Pulmonary arterial hypertension is a disorder of high mortality being described by progressive increase in pulmonary vascular strength leading to right ventricular damage and death. Endotelin-1 (ET-1) has an important pathogenic fuction hypertension. Bosentan oral ET-1 receptor antagonist that proved be efficient at exercise tolerance patients with functional class III IV. The early trial registered for II evaluated hemodynamic 6 month. Considerable side effects bosentan comprise anemia,...

10.37358/rc.20.2.7944 article EN cc-by Revista de Chimie 2020-03-03
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