Jiayan Chen

ORCID: 0000-0002-3425-8486
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About
Contact & Profiles
Research Areas
  • Ocular Surface and Contact Lens
  • Glaucoma and retinal disorders
  • Corneal surgery and disorders
  • Corneal Surgery and Treatments
  • Ophthalmology and Visual Impairment Studies
  • Radiomics and Machine Learning in Medical Imaging
  • Membrane Separation Technologies
  • Allergic Rhinitis and Sensitization
  • Intraocular Surgery and Lenses
  • Advanced Photocatalysis Techniques
  • Laser Applications in Dentistry and Medicine
  • Drug-Induced Hepatotoxicity and Protection
  • Membrane Separation and Gas Transport
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Ocular Infections and Treatments
  • Lymphoma Diagnosis and Treatment
  • Lung Cancer Treatments and Mutations
  • Liver Disease Diagnosis and Treatment
  • Catalytic Processes in Materials Science
  • Elevator Systems and Control
  • Barrier Structure and Function Studies
  • MRI in cancer diagnosis
  • Kruppel-like factors research
  • Advanced oxidation water treatment

He Eye Hospital
2022-2025

ShanghaiTech University
2024

Jinan University
2023-2024

Nanjing Medical University
2016-2024

Yunnan University
2024

Zhejiang Chinese Medical University
2024

Nanchang University
2020-2024

Lanzhou University of Technology
2024

China Jiliang University
2024

Nanjing General Hospital of Nanjing Military Command
2024

This paper concentrates on the elevator passenger detection task, a pivotal element for subsequent tracking and behavior recognition, crucial ensuring safety. To enhance accuracy of detecting positions inside elevators, we improved YOLOv8 network proposed SC-YOLOv8 with soft-pooling attention mechanisms. The main improvements in this encompass following aspects: Firstly, transformed convolution module (ConvModule) backbone by introducing spatial channel reconstruction (SCConv). improvement...

10.3390/app14083321 article EN cc-by Applied Sciences 2024-04-15

Background Overexpression of tear matrix metalloproteinases-9 (MMP-9) on the ocular surface tissues has been reported to result in damage. MMP-9 levels tears have listed as one many tools for confirming dry eye disease (DED). Objective This investigation aimed compare and parameters diabetic patients with without DED. Design A cross-sectional study. Setting He Eye Specialist Hospital, Shenyang, China. Participants study recruited 144 right eyes between November December 2023, 110 similar...

10.1136/bmjopen-2024-087530 article EN cc-by-nc-nd BMJ Open 2025-01-01

This study assessed the efficacy and safety of intense pulsed light (IPL) therapy in participants with severe evaporative dry eye disease (DED).This randomized, controlled, single-center included 49 adult (≥ 18 years) DED who received either IPL (n = 56 eyes) or sham 42 three times. The primary parameters were ocular surface index (OSDI) score, non-invasive tear breakup time (NITBUT), film lipid layer (TFLL), conjunctivocorneal staining score (CS), MG Score, meibomian gland (MG) quality,...

10.1007/s40123-023-00649-5 article EN cc-by-nc Ophthalmology and Therapy 2023-01-24

Statins are widely used lipid-lowering drugs, which have pleiotropic effects, such as anti-inflammation, and vascular protection. In our study, we investigated the radioprotective potential of simvastatin (SIM) in a murine model radiation-induced salivary gland dysfunction.Ninety-six Institute Cancer Research mice were randomly divided into four groups: solvent + sham irradiation (IR) (Group I), SIM IR II), III), IV). (10 mg/kg body weight, three times per week) was administered...

10.2147/dddt.s105809 article EN cc-by-nc Drug Design Development and Therapy 2016-07-01

Background Diabetes mellitus has been associated with increased dry eye disease (DED) and exacerbates DED pathology. Objective To investigate the potential relationship between corneal nerve loss ocular pain among diabetic patients (DE). Design A cross-sectional study. Setting He Eye Specialist Hospital, Shenyang, China. Participants This study recruited 124 eyes of 62 diagnosed August October 2022. Main outcome measures Best-corrected visual acuity, intraocular pressure, non-invasive tear...

10.1136/bmjopen-2023-076932 article EN cc-by-nc BMJ Open 2023-09-01

This study aimed to assess the change in pupil size and its influence on subjective quality of vision (QoV) subjects with implanted collamer lenses (ICLs). retrospective assessed 53 participants (53 eyes) ICL (V4c) categorized them into incremental groups according diameter. Preoperative postoperative photopic mesopic diameter, uncorrected distance visual acuity (UDVA), QoV questionnaire scores were compared. Postoperatively, at 3 months, UDVA was -0.10 ± 0.06 logarithm minimum angle...

10.1097/md.0000000000035198 article EN cc-by-nc Medicine 2023-10-06

Thioxanthones (TXs) are photoinitiators widely used in UV curable resins and food packaging, their residues have been frequently detected human bodies. Our current understanding of the susceptibility residual TXs to metabolism effects on health is very limited. The vitro its toxic cytochrome P450 (CYP) (the key xenobiotic metabolizing enzymes) were examined this study. 2-Chlorothioxanthone (2-Cl-TX) significantly inhibited enzymatic activities CYP1A2 CYP3A4 with IC50 8.36 0.86 μM,...

10.1021/acs.est.8b04643 article EN Environmental Science & Technology 2018-09-20

Background: Radiofrequency ablation (RFA) is a minimally invasive thermal technique. We conducted meta-analysis based on eligible studies to assess the efficacy and safety of RFA for treating patients with breast cancer. Methods: A literature search was in PubMed, Embase, Web Science databases. Eligible were clinical trials that assessed The outcomes included complete rate, recurrence excellent or good cosmetic rates, complication rate. random-effects fixed-effects model used pool estimate,...

10.2147/ott.s97828 article EN cc-by-nc OncoTargets and Therapy 2016-03-01

The primary objective of this study is to assess whether the combination intense pulsed light (IPL) with 3% diquafosol (DQS) ophthalmic solution more effective than in alleviating signs and symptoms dry eye disease (DED). This randomized included 66 participants evaporative (EDE) who received IPL + DQS therapy (n = 44 eyes), or sham eyes). All were examined at baseline (D0), day 14 (D14), 28 (D28) for non-invasive break-up time (NITBUT), tear-film lipid layer (TFLL), corneal conjunctival...

10.1007/s40123-023-00784-z article EN cc-by-nc Ophthalmology and Therapy 2023-08-17

Daily use of low concentrations atropine is recommended for children undergoing myopia control therapy. While the benefits controlling progression have been confirmed, potential unwanted side effects on ocular surface, pupil size, and quality vision following administration 0.01% not investigated.

10.3389/fmed.2024.1436551 article EN cc-by Frontiers in Medicine 2024-09-05

Background/PurposeMeibomian glands are sebaceous that release meibum onto the ocular surface; enhancing quality and quantity of secretions has been proven to improve signs symptoms evaporative dry eye (EDE) meibomian gland dysfunction (MGD). This study aimed evaluate compare efficacy a heated mask (HEM) eyelid massage device EyePeace (EP) in alleviating eye.MethodsForty participants were recruited prospective, contralateral-eye trial study. After undergoing 10 min HEM therapy, therapy was...

10.1016/j.heliyon.2024.e36590 article EN cc-by-nc-nd Heliyon 2024-08-20

Previous studies have demonstrated that apparent diffusion coefficient (ADC) values measured by magnetic resonance imaging prognostic value in patients with esophageal squamous cell carcinoma (ESCC). However, the role of ADC needs to be validated a cohort Chinese ESCC patients. This study assessed predicting outcome treated only chemoradiation People's Republic China.Seventy-three local advanced were retrospectively analyzed this study; none underwent surgery before or after chemoradiation....

10.2147/ott.s107466 article EN cc-by-nc OncoTargets and Therapy 2016-09-01

The New Chinese Diabetes Risk Score (NCDRS) is one of the recommended tools for screening undiagnosed type 2 diabetes in China. However, its performance detecting needs to be verified different community populations. Also, it unknown whether NCDRS can used prediabetes. In present study, we aimed evaluate and prediabetes among residents eastern We applied 7675 aged 18-65 years old Jiangsu Province. results showed that participants with reported highest value, followed by those (<mml:math...

10.1155/2020/7463082 article EN cc-by Journal of Diabetes Research 2020-04-30

Introduction Evaporative dry eye (EDE) is common and can lead to ocular pain, decreased visual quality reduced of life. Intense pulsed light (IPL) 3% diquafosol ophthalmic solution have been found be beneficial in reducing signs symptoms eye. Methods analysis A randomised clinical trial will performed at He Eye Specialist Hospital Shenyang. 360 disease patients equally divided randomly into the IPL group, DQS group (3% eye-drops) IPL+group (IPL combined with eye-drops). All groups followed...

10.1136/bmjopen-2023-073055 article EN cc-by-nc BMJ Open 2023-08-01

Diabetes mellitus has been associated with increased dry eye disease (DED) and exacerbates DED's pathology. This preliminary short-term study aimed to evaluate the effects of 3% Diquafosol Sodium ophthalmic solution (DQS) on ocular surface inflammation corneal nerve density in diabetic (DDE) patients.

10.1089/jop.2023.0098 article EN Journal of Ocular Pharmacology and Therapeutics 2023-12-15

The objective of this study was to assess the effectiveness intense pulsed light (IPL) therapy in individuals diagnosed with glaucoma and dry eye disease (DED).

10.2147/opth.s471426 article EN cc-by-nc Clinical ophthalmology 2024-07-01
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