- Ophthalmology and Visual Impairment Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Glaucoma and retinal disorders
- Pediatric health and respiratory diseases
- Corneal surgery and disorders
- Ergonomics and Musculoskeletal Disorders
- Tendon Structure and Treatment
- Health Literacy and Information Accessibility
- Metabolism, Diabetes, and Cancer
- Diabetes Management and Education
- Tissue Engineering and Regenerative Medicine
- Cardiovascular Health and Risk Factors
- Medical Research and Treatments
- Health and Wellbeing Research
- Shoulder Injury and Treatment
- Liver Disease Diagnosis and Treatment
- Growth Hormone and Insulin-like Growth Factors
- Folate and B Vitamins Research
- Mobile Health and mHealth Applications
- SARS-CoV-2 and COVID-19 Research
- Visual perception and processing mechanisms
- Diabetes Management and Research
- Chronic Disease Management Strategies
- Cancer Cells and Metastasis
- Social Media in Health Education
Nanjing Agricultural University
2024
Hubei University of Science and Technology
2019-2023
Hunan Provincial Science and Technology Department
2022-2023
He Eye Hospital
2022-2023
First Affiliated Hospital of Heilongjiang University of Chinese Medicine
2023
Affiliated Hospital of Shaanxi University of Chinese Medicine
2022-2023
Yunnan University of Traditional Chinese Medicine
2022
Jiangsu Provincial Center for Disease Control and Prevention
2012-2022
Guangzhou Center for Disease Control and Prevention
2022
Guangzhou Medical University
2022
Aim To reassess the association between near work, outdoor exposure and myopia in children through an objective approach. Methods Eighty-six (10.13±0.48 years) were asked to wear Clouclip, a newly developed wearable device that is able measure working distance eye-level illuminance, for complete week obtain information on work exposure. The mean daily Clouclip wearing time was 11.72±1.14 hour. spherical equivalent refraction determined by cycloplegic autorefraction. Results myopic found be...
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 has become an important public health issue in world. More than 118 000 cases were confirmed around The main clinical manifestations symptoms and occasional gastrointestinal symptoms. However, there is no unified standard for diagnosis treatment of COVID-19. In retrospective analysis, we report nine COVID-19, describe history contact, manifestations, course before, during after treatment.
Health literacy has become an important public health concern. Multistage cluster random sampling was used to select 12 450 individuals. Using the 2009 Chinese Literacy questionnaire, participants were divided into groups with poor or not status. The knowledge rates for 6 areas of determined following results: science concept (60.0%), preventing acute infectious disease (66.8%), noncommunicable chronic (51.9%), safety and first aid obtaining making use basic medical care (55.3%),...
Depression is a widely recognized neuropsychiatric condition that often occurs as comorbidity with various medical illnesses, including neurodegenerative disorders like Parkinson's disease (PD). This study aimed to identify the age of onset and underlying characteristics associated patients exhibiting mild moderate depression comorbid PD. retrospective case-control included 114 elderly (age ≥65 years) diagnosed disease. The were divided into two groups: non-depressed group (n = 65) 49)....
Background Due to the increase incidents of premarital sex and lack reproductive health services, college students are at high risk HIV/AIDS infections in China. This study was designed examine predictors consistency condom use among based on Information-Motivation-Behavioral Skills (IMB) model describe relationships between constructs. Methods A cross-sectional conducted assess related information, motivation, behavioral skills preventive behavior five colleges universities Nanjing, An...
Abstract Introduction: The study aimed to determine the effectiveness of an intervention for unhealthy visual behaviors school-age children using a wearable device (Clouclip). Method: design was self-controlled prospective study. Clouclip, with vibration alert disabled, first applied measure baseline near-work in week. then enabled signal (near-work distance < 30 cm and >5 seconds, or <60 >45 minutes) 3 weeks. Near-work were measured again at week month after intervention,...
To compare light intensity and near-visual tasks objectively between rural urban children.Clouclip, a wearable device, was applied to assess metrics of these two factors in 78 fifth-grade students from an school.The experienced by found significantly lower both the school period (614.05 ± 178.77 vs. 918.41 257.81 lux, P < 0.001) on weekend (444.53 216.65 882.21 536.67 0.001). The duration exposure bright (>1000 lux) also substantially shorter for students. Although no significant difference...
Tissue engineering has exhibited great effect on treatment for bone-tendon interface (BTI) injury. The aim of this study was to evaluate the a book-shaped acellular tendon scaffold (ATS) with bone marrow mesenchymal stem cells sheets (MSCS) BTI injury repair. ATS designed based shape "book", decellularization evaluated by Hematoxylin and eosin (H&E), 4', 6-diamidino-2-phenylindole (DAPI) scanning electron microscopy (SEM), then (MSCs) were cultured assess differentiation inductivity ATS. A...
Background: More than 450,000 rotator cuff repairs are performed annually, yet healing of tendon to bone often fails. This failure is rooted in the fibrovascular response, which does not regenerate native attachment site. Better outcomes may be achieved by targeting inflammation during early period after repair. Rather broad inhibition inflammation, impair healing, current study utilized a molecularly targeted approach suppress IKKβ, shutting down only inflammatory arm nuclear factor κB...
Dyslipidaemia is a risk factor for abnormal blood glucose. However, studies on the predictive values of lipid markers in prediabetes and diabetes simultaneously are limited. This study aimed to assess associations abilities indices glucose.A sample 7667 participants without were enrolled this cross-sectional conducted 2016, all them classified as having normal glucose tolerance (NGT), or diabetes. Blood glucose, pressure parameters (triglycerides, TG; total cholesterol, TC; high-density...
A spiro ent-clerodane homodimer with a rare 6/6/6/6/6-fused pentacyclic scaffold, spiroarborin (1), together four new monomeric analogues (2-5), were isolated from Callicarpa arborea. Their structures elucidated by comprehensive spectroscopic data analysis, quantum-chemical calculations, and X-ray diffraction. plausible biosynthetic pathway of 1 was proposed, biomimetic synthesis its derivative accomplished. Compound showed potent inhibitory effect directly binding to the YEATS domain 11-19...
A series of bis(l-amino acid) ester prodrugs tenofovir (TFV) were designed and synthesized as new anti-HBV agents in this work. Four compounds 11, 12a, 12d, 13b displayed better activity (IC50: 0.71–4.22 μM) than the parent drug TFV. The most active compound 11 0.71 μM), a bis(l-valine) prodrug TFV, was found to have obviously greater AUC0–∞, Cmax, F% disoproxil fumarate (TDF), potent vivo efficacy which is not inferior TDF duck HBV (DHBV) model DNA hydrodynamic mouse model, it may serve...
Although fasting plasma glucose (FPG) has been highly recommended as the sole test for diabetes screening, efficacy of FPG alone screening is potentially limited due to its low sensitivity. The aim this study was improve using urinary (UG).This initiated on November 12, 2015, and ended June 28, 2016. A representative sample individuals aged between 18 65 years, with no history diabetes, from 6 cities in Jiangsu Province participated study. 75-g oral tolerance used diagnose diabetes. All...
Purpose: The purpose of this study was to explore two-dimensional peripheral refraction and higher-order aberrations (HOAs) induced by orthokeratology lens decentration. Methods: Two-dimensional HOAs in a rectangular field (horizontally 60 degrees vertically 36 degrees) were obtained using an open-view Hartmann–Shack wavefront sensor. divided into 8 regions according combination superior (UZ) or inferior (LZ) value, 1 (T25 T30), 2 (T20 T25), 3 (N20 N25), 4 (N25 N30). decentration the...
The deleterious effects of psychosocial outcomes on diabetic patients' health have not been fully investigated yet. This study was aimed to explore how impacted the status Chinese patients with type 2 diabetes.A mix stratified sampling and typical were used select in Jiangsu Province conduct individual interviews. Health measured by EuroQol Visual Analogue Scale (VAS). Psychosocial instruments Diabetes Attitudes, Wishes Needs survey, including psychological well-being, diabetes distress,...
Objective: To assess the reliability and validity of Chinese version on Alcohol Use Disorders Identification Test (AUDIT) among medical students in China to provide correct way application recommended scales. Methods: An E-questionnaire was developed sent five different colleges. Students were all active volunteers accept testings. Cronbach's α split-half calculated evaluate AUDIT while content, contract, discriminant convergent performed measure Results: The overall 0.782 0.711. Data showed...
The New Chinese Diabetes Risk Score (NCDRS) is one of the recommended tools for screening undiagnosed type 2 diabetes in China. However, its performance detecting needs to be verified different community populations. Also, it unknown whether NCDRS can used prediabetes. In present study, we aimed evaluate and prediabetes among residents eastern We applied 7675 aged 18-65 years old Jiangsu Province. results showed that participants with reported highest value, followed by those (<mml:math...
This retrospective study investigated circulating immune cell alteration in patients with myopic retinopathy. Blood test results and demographic ocular information of 392 129 emmetropia controls who attended Changsha Aier Eye Hospital from May 2017 to April 2022 were used this study. Compared emmetropia, the percentages neutrophils basophils neutrophil/lymphocyte ratio significantly higher patients, whereas monocytes lymphocytes counts eosinophils lower patients. After adjusting for age...
The hVE-cad-Fc matrix promotes the self-reconstruction of pro-vascularization microenvironments and endothelial differentiation hMSCs.