A5101783739- Healthcare Systems and Reforms
- Traditional Chinese Medicine Analysis
- Global Health Care Issues
- Maternal Mental Health During Pregnancy and Postpartum
- Ginseng Biological Effects and Applications
- Cardiovascular Function and Risk Factors
- Traditional Chinese Medicine Studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Lipid metabolism and disorders
- Mesenchymal stem cell research
- Parkinson's Disease Mechanisms and Treatments
- Pancreatic function and diabetes
- HIV/AIDS Research and Interventions
- Diabetes Management and Research
- Endoplasmic Reticulum Stress and Disease
- Cardiac Arrhythmias and Treatments
- Adolescent Sexual and Reproductive Health
- Treatment of Major Depression
- Medical Research and Treatments
- Trauma and Emergency Care Studies
- Tryptophan and brain disorders
- Cardiac Fibrosis and Remodeling
- Spaceflight effects on biology
- Global Public Health Policies and Epidemiology
- Natural Compounds in Disease Treatment
Icahn School of Medicine at Mount Sinai
2023-2025
First Affiliated Hospital of Xiamen University
2024-2025
Allen Institute for Brain Science
2025
Guangdong Province Women and Children Hospital
2024
National Health and Family Planning Commission
2018-2024
First Hospital of Jiaxing
2024
Hainan Provincial Hospital of Traditional Chinese Medicine
2007-2024
Clinical Trial Investigators
2024
Shanxi Medical University
2013-2023
University of Pittsburgh
2023
China has about 350 million smokers, more commonly men. Using data from National Health Service Surveys conducted in 1993, 1998 and 2003, we (i) estimated trends smoking prevalence cessation according to sociodemographic variables (ii) analysed rates, quitting intentions, reasons for relapsing.Data were collected approximately 57 000 households 200 individuals each survey year. Household members > 15 years of age interviewed their habits, intentions attitudes towards smoking. We present...
Abstract Stem cells are promising for the treatment of myocardial infarction (MI) and large animal models should be used to better understand full spectrum stem cell actions preclinical evidences. In this study, bone marrow mesenchymal (BM-MSCs) were transplanted into swine heart ischemia model. To detect glucose metabolism in global left ventricular myocardium regional myocardium, combined with assessment cardiac function, positron emission tomography-computer tomography (PET-CT) magnetic...
Environmental bacteria, nontuberculous mycobacteria (NTM), are recognized as one of the major human infection pathogens. NTM prone to be mistaken multidrug-resistant Mycobacterium tuberculosis and challenge our fight against TB. In addition, treatment per se is intractable. Remarkably, distribution pathogenic species geographically specific. Thus, it very important summarize prevalent features clinical symptoms pulmonary disease. However, Nanjing district, southeast China, there no such a...
Over the past 25 years, spectrum of diseases in China has rapidly changed from infectious to non-communicable (NCDs). This study aimed identify prevalence chronic over years and estimate trends changes risk factors related NCDs.We conducted a descriptive analysis based on National Health Service Survey (NHSS) 1993 2018. The survey year (in parentheses) its respective number respondents were (1993) 215,163; (1998) 216,101; (2003) 193,689; (2008) 177,501; (2013) 273,688; (2018) 256,304. In...
Abstract Background Aging is associated with an increased prevalence of non-communicable chronic diseases (NCDs), functional impairments, and diverse demands for health services. This study analyzed the trends in older adults’ needs utilization services from 1993 to 2018 China, as well disease-related economic burdens. Methods The research data were collected six cross-sectional National Health Service Survey (NHSS), implemented every 5 years 2018. A multi-stage stratified random cluster...
Stroke has severe consequences in postmenopausal women.As replacement therapy of estrogen have various adverse effects and the undermined outcomes.Genistein, a natural phytoestrogen, been suggested to be potential neuroprotective agent for such stroke patients.However, role genistein its underlying mechanism ovariectomized mice not yet evaluated.In present study, were treated with (10 mg/kg) or vehicle daily two weeks before developing transient cerebral ischemia (middle artery...
Background Our prior study in Han Chinese women has shown that with a history of childhood sexual abuse (CSA) are at increased risk for developing major depression (MD). Would this relationship be found our whole data set? Method Three levels CSA (non-genital, genital, and intercourse) were assessed by self-report two groups women: 6017 clinically ascertained recurrent MD 5983 matched controls. Diagnostic other factor information was personal interview. Odds ratios (ORs) calculated logistic...
The terrifying undiagnosed rate and high prevalence of diabetes have become a public emergency. A efficiency cost-effective early recognition method is urgently needed. We aimed to generate innovative, user-friendly nomograms that can be applied for screening in different ethnic groups China using the non-lab or noninvasive semi-lab data.This multicenter, multi-ethnic, population-based, cross-sectional study was conducted eight sites by enrolling subjects aged 20-70. Sociodemographic...
Major Depressive Disorder (MDD) is a devastating, multifactorial disease with limited pharmacological treatment options. Patients MDD exhibit alterations in their dopamine (DA) signaling pathways through the midbrain ventral tegmental area (VTA). A similar observation also detected preclinical models of stress - mice behavioral and physiological impairments following chronic social defeat (CSDS). Prior studies demonstrate that CSDS-susceptible have increased VTA DA neuronal excitability,...
Abstract Background Supplemental private health insurance (PHI) plays a crucial role in complementing China’s social (SHI). However, the effectiveness of incorporating PHI as supplementary coverage lacks conclusive evidence regarding its impact on healthcare utilization and seeking behavior among SHI-covered individuals. Therefore, investigating effects care residents covered by is essential to provide empirical for informed decision-making within Chinese system. Methods Data from 2018 China...
Abstract Calcium homeostasis in osteoblasts plays fundamental roles the physiology and pathology of bone tissue. Various types mechanical stimuli promote osteogenesis increase formation elicit increases intracellular‐free calcium concentration osteoblasts. However, whether microgravity, a condition unloading, exerts an influence on or what mechanisms may underlie such effect are unclear. Herein, we show that simulated microgravity reduces primary mouse In addition, substantially suppresses...
Repeated, long-term (weeks to months) exposure standard antidepressant medications is required achieve treatment efficacy. In contrast, acute ketamine quickly improves mood for an extended time. Recent work implicates that hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are involved in mediating ketamine's effects. this study, we directly targeted HCN and achieved ketamine-like rapid sustained Our vitro electrophysiological recordings first showed inhibitor DK-AH 269 (also...