A5081408313- Viral Infections and Vectors
- Luminescence Properties of Advanced Materials
- Brucella: diagnosis, epidemiology, treatment
- Viral Infections and Outbreaks Research
- Diagnosis and treatment of tuberculosis
- Liver Disease Diagnosis and Treatment
- Tuberculosis Research and Epidemiology
- Parasites and Host Interactions
- Amoebic Infections and Treatments
- Liver Disease and Transplantation
- Electrocatalysts for Energy Conversion
- Escherichia coli research studies
- Lung Cancer Diagnosis and Treatment
- RNA modifications and cancer
- Nanoplatforms for cancer theranostics
- Salmonella and Campylobacter epidemiology
- Fire effects on ecosystems
- Epigenetics and DNA Methylation
- Catalytic Processes in Materials Science
- Solid State Laser Technologies
- Mycobacterium research and diagnosis
- Mesenchymal stem cell research
- vaccines and immunoinformatics approaches
- Helminth infection and control
- Immunotherapy and Immune Responses
First Affiliated Hospital of Wannan Medical College
2007-2025
Beijing University of Chinese Medicine
2024-2025
Shenyang Agricultural University
2020-2025
Ministry of Agriculture and Rural Affairs
2025
Wannan Medical College
2006-2024
State Key Laboratory of Pollution Control and Resource Reuse
2024
Nanjing University
2023-2024
Guilin University of Technology
2022-2024
Second Hospital of Shanxi Medical University
2024
Shanxi Medical University
2024
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 has become an important public health issue in world. More than 118 000 cases were confirmed around The main clinical manifestations symptoms and occasional gastrointestinal symptoms. However, there is no unified standard for diagnosis treatment of COVID-19. In retrospective analysis, we report nine COVID-19, describe history contact, manifestations, course before, during after treatment.
Abstract Objectives Bone marrow mesenchymal stem cells (BMSCs) hold a high osteogenic differentiation potential, but the mechanisms that control ability of BMSCs from osteoporosis (OP‐BMSCs) need further research. The purpose this experiment is to discuss effect Mettl3 on OP‐BMSCs and explore new therapeutic target can enhance bone formation OP‐BMSCs. Materials Methods bilateral ovariectomy (OVX) method was used establish SD rat OP model. Dot blots were reveal different methylation levels...
A number of epidemiological and clinical studies have suggested an inverse association between allergy helminth infection, such as Schistosomiasis. Therefore, we hypothesize that Schistosoma japonicum egg antigens, a type native antigen, can induce production CD4(+) CD25(+) T cells with regulatory activity, modulating airway inflammation inhibiting asthma development. The frequency was determined by flow cytometry for mice treated ovalbumin (OVA), depletion/OVA, schistosome antigens/OVA...
This study aims to develop a dynamic nomogram model using machine learning improve short-term prognosis prediction and identify patients who would benefit from intravenous immunoglobulin (IVIG) therapy. A multicenter retrospective was conducted on 396 diagnosed with SFTS. Univariate multivariate Cox regression analyses identified significant predictors of mortality. Machine models, including Random Survival Forest, Stepwise Modeling, Lasso Regression, were compared for their predictive...
Metformin is the first line of oral antidiabetic drug in biguanide class for treatment type 2 diabetes. Increasing evidence has suggested that it a potential anti-tumor drug. However, mechanisms underlying inhibiting tumor development remain elusive, especially bladder tumors. T24 and J82 cell lines were used as an vitro model, 24 female SD rats to build N-methyl-N-nitrosourea (MNU)-induced orthotopic rat cancer model. Transfection lentivirus-based shRNA was construct STAT3-KNOCKDOWN line....
NaYF4 as the core and NaGdF4 outer layer were used to obtain NaYF4:Yb3+/Tm3+@NaYF4:Ce3+/Eu3+ nanoparticles. Physical morphological investigations indicated that obtained nanoparticles prepared in a hexagonal shape, with shell uniformly encapsulated on core. Strong Tm3+ upconversion emission peaks observed for 980-nm-laser-excited sample, while strong Eu3+ downconversion 254-nm-laser-excited sample. By zonal doping of Eu3+, their fluorescence intensity can be significantly increased; more...
By doping Tm 3+ and Er with core–shell partitioning, not only a significant increase in fluorescence intensity could be achieved, but also simultaneous temperature measurements on multiple thermocouple energy levels realised.
Abstract Background Diabetes-related osteoporosis (DOP) is a chronic disease caused by the high glucose environment that induces metabolic disorder of osteocytes and osteoblast-associated mesenchymal stem cells. The processes bone defect repair regeneration become extremely difficult with DOP. Adipose-derived cells (ASCs), as seed in tissue engineering technology, provide promising therapeutic approach for DOP patients. osteogenic ability ASCs lower model than control ASCs. DNA methylation,...
The guided tissue regeneration (GTR) technique is a promising treatment for periodontal defects. GTR membranes build mechanical barrier to control the ingrowth of gingival epithelium and provide appropriate space tissues, particularly alveolar bone. However, existing only serve as barriers lack biological activity induce bone regeneration. In this study, sericin-hydroxyapatite (Ser-HAP) composite nanomaterials were fabricated using biomimetic mineralization method with sericin an organic...
Abstract Severe fever with thrombocytopenia syndrome (SFTS) is a widespread infectious disease high mortality. Hence, identifying valuable biomarkers for detecting the early changes in SFTS crucial. In this study, we investigated relationship between difference hematocrit (HCT) and serum albumin (ALB) levels (HCT‐ALB) prognosis of patients virus infection. After excluding who did not meet diagnostic criteria, those from First Affiliated Hospital Wannan Medical College were divided into fatal...
Although the Asian Pacific Association for Study of Liver acute-on-chronic liver failure (ACLF) research consortium (AARC) ACLF score is easy to use in patients with hepatitis b virus-related (HBV-ACLF), serum lactate not routinely tested primary hospitals, and its value may be affected by some interference factors. Neutrophil-to-lymphocyte ratio (NLR) used assess status bacterial infection (BI) or outcomes various diseases. We developed an NLR-based AARC compared it existing model.A total...
Abstract Antigen delivery based on non‐virus‐like particle self‐associating protein nanoscffolds, such as Aquifex aeolicus lumazine synthase (AaLS), is limited due to the immunotoxicity and/or premature clearance of antigen‐scaffold complex resulted from triggering unregulated innate immune responses. Here, using rational immunoinformatics prediction and computational modeling, we screen T epitope peptides thermophilic nanoproteins with same spatial structure hyperthermophilic icosahedral...
Abstract With the widespread use of social media platforms, human-technology interactions in platform environments provide a new perspective for understanding digital inequality. This article constructs conceptual framework through analytical tool “platform affordance” to reveal how mutual construction humans and technology extends boundaries inequality beyond structural factors. The considers positive sequential relationship between technology-efficacy self-efficacy, highlighting their...
Abstract To explore the association and impact between viral myocarditis mortality in patients with severe fever thrombocytopenia syndrome. A dynamic analysis was conducted fatal group nonfatal regarding daily epidemiology data, clinical symptoms, electrocardiogram (ECG), echocardiogram, laboratory findings. Outcomes of without were compared. The analyzed. Among 183 syndrome patients, 32 151 group; there 26 (81.25%) group, 66 (43.70%) ( p < 0.001), 79.35% had abnormal ECG results. rate...
Radiation pneumonitis (RP) is a severe complication of thoracic radiotherapy that may lead to dyspnea and lung fibrosis, negatively affects patients' quality life.To carry out multiple regression analysis on the influencing factors radiation pneumonitis.Records 234 patients receiving chest in Huzhou Central Hospital (Huzhou, Zhejiang Province, China) from January 2018 February 2021, were divided into either study group or control based presence not. Among them, 93 with included 141 without...
Patients with schistosomal colorectal cancer (CRC) and nonschistosomal CRC have different clinicopathological features, laboratory test results survival rates. Long-term infection schistosomiasis in patients may affect the pathogenesis subsequently change mechanisms of these patients, resulting changes rates CRC. In China, most common type is S. japonicum. The present study aimed to investigate features prognostic factors A total 253 2,885 were analyzed their symptoms, retrospectively...
Au-graphene quantum dots (GQDs)@Pt core–shell nanodendrites are synthesized through a two-step reduction approach, in which Au forms the core, GQDs form an intermediate layer and dendritic Pt shell. Among above catalysts, can manipulate binding of reaction intermediates on surface as well assemble π–π* conjugate bonds, thus forming shell instead compact The obtained structure was characterized by transmission electron microscopy, energy-dispersive x-ray photoelectron spectroscopy. methanol...