A5017749161- Clinical Laboratory Practices and Quality Control
- Meta-analysis and systematic reviews
- Reliability and Agreement in Measurement
- Renal function and acid-base balance
- Statistical Methods in Clinical Trials
- Hemodynamic Monitoring and Therapy
- Quality and Safety in Healthcare
- Bacterial Identification and Susceptibility Testing
- Healthcare cost, quality, practices
- Chronic Kidney Disease and Diabetes
- Dialysis and Renal Disease Management
- Body Composition Measurement Techniques
- Viral Infections and Outbreaks Research
- Birth, Development, and Health
- Enzyme-mediated dye degradation
- Acute Kidney Injury Research
- Disaster Response and Management
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Pituitary Gland Disorders and Treatments
- Pregnancy and preeclampsia studies
- Clinical Reasoning and Diagnostic Skills
- Traumatic Brain Injury and Neurovascular Disturbances
- Adrenal Hormones and Disorders
- Biosimilars and Bioanalytical Methods
- Hepatitis B Virus Studies
Sociedad Española de Medicina Interna
2019-2022
Hospital Universitario La Paz
2013-2022
Hospital La Paz Institute for Health Research
2017
Universidad Autónoma de Madrid
2016-2017
Atatürk University
2014
University Hospital in Motol
2014
Charles University
2014
Imam Mohammad ibn Saud Islamic University
2014
Bolu Abant İzzet Baysal University
2014
Universidad de Valladolid
2003-2008
Introduction The present study describes the distribution of selected micronutrients and anaemia among school-aged children living in Libo Kemkem Fogera (Amhara State, Ethiopia), assessing differences by socio-demographic characteristics, health status dietary habits. Methods A cross-sectional survey was carried out during May–December 2009. Socio-demographic habits were collected. Biomarkers determined for 764 children. Bivariate multivariable statistical methods employed to assess...
Abstract To ensure that clinical laboratories produce results are both accurate and of utility it is essential only samples adequate quality analysed. Although various studies databases assessing the stability analytes in different settings do exist, guidance on how to perform report lacking. This often not information, thus compromising transferability data. The aim this manuscript describe C hecklist for R eporting S tability tudies (CRESS) against which future should be reported...
Abstract Objectives Knowledge of the stability analytes in clinical specimens is a prerequisite for proper transport and preservation samples to avoid laboratory errors. The new version ISO 15189:2022 European directive 2017/746 increase requirements on this topic manufacturers laboratories. Within project generate database Federation Clinical Chemistry Laboratory Medicine (EFLM) Working Group Preanalytical Phase (WG-PRE), need standardise improve quality published studies has been detected,...
Abstract Breast cancer is a heterogeneous disease comprising variety of entities with various genetic backgrounds. Estrogen receptor-positive, human epidermal growth factor receptor 2-negative tumors typically have favorable outcome; however, some patients eventually relapse, which suggests heterogeneity within this category. In the present study, we used proteomics and miRNA profiling techniques to characterize set 102 either estrogen receptor-positive (ER+)/progesterone (PR+) or...
The stability of plasma samples for basic coagulation tests, prothrombin time (PT) and activated partial thromboplastin (aPTT), has been widely studied. Recently, the Clinical Laboratory Standards Institute (CLSI) updated its recommendations, extending acceptable frame aPTT. These guidelines are based on experimental studies, which define limits according to different maximum permissible error (MPE) criteria. This study compiles raw data from 43 studies published over last 30 years develop a...
Resumen Objetivos La gestión de indicadores calidad (IC) es una herramienta óptima para monitorizar y mejorar el desempeño en las fases extraanalíticas del Laboratorio Clínico (LC). Por este motivo, la Sociedad Española Medicina (SEQC ML ) lanzó 2001 Programa Preanalítica. Métodos En 2023 se realizó encuesta evaluar grado participación valorar necesidad mejora, así como conocer procedimiento recogida cálculo IC extraanalíticos. Resultados El 51 % los encuestados (124 respuestas total)...
Abstract Stability of a measurand in specimen is function the property variation over time specific storage conditions, which can be expressed as stability equation, and usually simplified to limits (SLs). studies show differences or even inconsistent results due lack standardized experimental designs heterogeneity chosen specifications. Although guidelines for validation sample collection tubes have been published recently, evaluation not addressed. This document provides an easy guideline...
In June, 1997, we initiated a prospective study to analyze the effect of granulocyte colony-stimulating factor (G-CSF) on coagulation system in peripheral blood stem cells (PBSC) donors following G-CSF administration. Since, 25 consecutively healthy received (filgrastim) mobilize and collect PBSC 20 were finally included study. Blood samples collected immediately before starting prior collection parameters: prothrombin time (PT), activated partial thromboplastin (APTT), fibrinogen,...
Preanalytical variables, such as sample collection, handling and transport, may affect patient results. phase quality monitoring should be established in order to minimize laboratory errors improve safety.A retrospective study (2001-2013) of the results obtained through Spanish Society Clinical Biochemistry Molecular Pathology (SEQC) External assessment (preanalytical phase) was performed summarize data regarding main factors affecting preanalytical quality. Our aim compare from 2006 2013...
Background: Verification uses logical algorithms to detect potential errors before laboratory results are released the clinician. Even though verification is one of main processes in all laboratories, there a lack standardization mainly used and criteria limits applied. A survey clinical laboratories Spain was conducted order assess process, particularly use autoverification.
Abstract Introduction Sample stability can be influenced by many different factors; evaporation and leakage from residual cells are the most relevant factors for electrolytes. During analytical phase, samples usually kept uncapped at room temperature. Once processed, they stored sealed refrigerated. Long turnaround time possibility of “add-on test” need consideration electrolyte stability. The aim our study is to examine short-term in this two-common laboratory working conditions two lithium...
High quality laboratory results are critical for patient management. However, poor sample can impact these and safety. To ensure reliable accurate laboratories must be aware of each analyte's stability under various storage conditions matrices to guarantee correct dependable outcomes. This knowledge allows define the allowable delay between collection centrifugation/analysis all analytes appropriate interpretation. The EFLM Working Group Preanalytical Phase (WG-PRE) therefore established a...
Contamination of blood samples from patients receiving intravenous fluids is a common error with potential risk to the patient. Algorithms based on presence aberrant results have been described but limitation that not all infusion same composition. Our objective develop an algorithm detection dilution observed analytes usually included in fluids.A group 89 cases was selected flagged as contaminated. confirmed by reviewing clinical history and comparing previous subsequent samples. A control...
Background Before an analyzer is replaced by another in a clinical laboratory, the analytical performance of new device and comparison with reference or already established method must be performed before use on patient samples. In point care, large numbers instruments are used, it necessary that all compared against laboratory instrument. According to these considerations, aim this study was evaluate 23 blood gas analyzers. Methods Three types evaluation were conducted. These included...
The objective of the present study was to examine evolution analytical performance specifications (APS) used in External Quality Assurance (EQA) schemes, as well efficacy a category 1 EQA scheme monitoring harmonization clinical laboratory results Spain.A review literature on types quality schemes other countries and their performed. In addition, comparative analysis potential impact that different APS from eight had decision-making made based three measurands: sodium, thyroid-stimulating...
Introduction: Technological innovation requires the laboratories to ensure that modifications or incorporations of new techniques do not alter quality their results. In an ISO 15189 accredited laboratory, flexible scope accreditation facilitates inclusion these changes prior body evaluation. A strategy perform validation a biochemistry analyzer in laboratory having is shown.