A5089460078- Genomics and Phylogenetic Studies
- RNA and protein synthesis mechanisms
- Bacteriophages and microbial interactions
- Biochemical Analysis and Sensing Techniques
- Microbial infections and disease research
- Mycobacterium research and diagnosis
- Estrogen and related hormone effects
- Environmental Toxicology and Ecotoxicology
- Plant Disease Resistance and Genetics
- Reproductive Physiology in Livestock
- Genetic diversity and population structure
- Garlic and Onion Studies
- Microbial Natural Products and Biosynthesis
- Protist diversity and phylogeny
- Date Palm Research Studies
- Helminth infection and control
- Genetics, Bioinformatics, and Biomedical Research
- Human Health and Disease
- Genetic and phenotypic traits in livestock
- Immune Response and Inflammation
- Ziziphus Jujuba Studies and Applications
- Veterinary Medicine and Surgery
- Metabolism and Genetic Disorders
- Natural Antidiabetic Agents Studies
- Aldose Reductase and Taurine
Ain Shams University
2015-2024
University of Konstanz
2023-2024
Mohammed V University
2024
Waukegan Public Library
2024
Czech Agrifood Research Center
2023
Czech Academy of Sciences, Biology Centre
2016-2022
Czech Academy of Sciences
2021-2022
Institute of Plant Molecular Biology
2020-2022
Benha University
2022
Institute of Parasitology
2016-2021
The African BioGenome Project (AfricaBP) is a Pan-African initiative aimed at improving food systems and biodiversity conservation through genomics while ensuring equitable data sharing benefits. Open Institute the knowledge exchange platform of AfricaBP which aims to bridge local gaps in bioinformatics enable infrastructural developments. In 2024, advanced this mission by organising 31 workshops that attracted more than 3500 registered attendees trained 380 researchers genomics,...
PWWP-Domain Interactor of Polycombs 1 (PWO1), also known as PWWP1, interacts with the catalytic subunits Polycomb Repressive Complex 2 (PRC2) and, together PWO2/3 proteins, plays a critical role in development Arabidopsis thaliana (At). PWOs are unique to plants and impact chromatin structure by enabling crosstalk between active repressive epigenetic marks through mechanisms that not yet fully understood. We aimed understand evolution PWO proteins whether their interaction PRC2 has been...
Knowledge on genetic diversity and structure of camel populations is fundamental for sustainable herd management breeding program implementation in this species. Here we characterized a total 331 camels from Northern Africa, representative six thirteen Algerian Egyptian geographic regions, using 20 STR markers. The nineteen polymorphic loci displayed an average 9.79 ± 5.31 alleles, ranging 2 (CVRL8) to 24 (CVRL1D). Average He was 0.647 0.173. Eleven deviated significantly Hardy-Weinberg...
In view of the widespread use pomegranate seeds for therapeutic purposes it was decided to study oestrogenic activity seed oil, which has not been investigated previously. The effect oil tested in immature rabbits by uterine weight method and ovariectomized mice vaginal smear technique. results were evaluated Robson (1938). Immature injected with daily 10 days, killed without anaesthesia their uteri weighed. Mature albino mice, weighing about 35g. ovariectomized, morning evening two...
Heavy metal pollution is an increasing global concern. Among heavy metals, mercury (Hg) especially dangerous because of its massive release into the environment and high toxicity, for aquatic organisms. The molecular response mechanisms algae to Hg exposure are mostly unknown. Here, we combine physiological, biochemical, transcriptomic analysis provide, first time, a comprehensive view on pathways activated in Chromera velia toxic levels Hg. Production hydrogen peroxide superoxide anion, two...
Polycomb repressive complex 2 (PRC2) is involved in maintaining transcriptionally silent chromatin states through methylating lysine 27 of histone H3 by the catalytic subunit enhancer zeste [E(z)]. Here, we report diversity PRC2 core proteins different eukaryotic supergroups with emphasis on early-diverged lineages and explore molecular evolution subunits phylogenetics. For first time, identify putative ortholog E(z) Discoba, a lineage hypothetically proximal to root, strongly supporting...
Genetic diversity and population structure studies of local olive germplasm are important to safeguard biodiversity, for genetic resources management improve the knowledge on distribution evolution patterns this species. In present study Algerian was characterized using 16 nuclear (nuSSR) six chloroplast (cpSSR) microsatellites. varieties, collected from National Olive Germplasm Repository (ITAFV), 10 which had never been genotyped before, were analyzed. Our results highlighted presence an...
The antidiabetic activity of different plants was tested in rats using the alloxan diabetes method. fasting blood sugar and adrenaline hyperglycaemia methods. Mulberry leaves, blackberry onion tops, green bean pods baker's yeast showed good effects. On other hand, lettuce coriander fruit, chicory leaves bryony root were without any prominent action. Further investigation is still hands.
Wheat dwarf virus (WDV) is one of the most important pathogens cereal crops worldwide. To understand molecular mechanism resistance, here we investigated comparative transcriptome wheat genotypes with different levels resistance (Svitava and Fengyou 3) susceptibility (Akteur) to WDV. We found a significantly higher number differentially expressed transcripts (DETs) in susceptible genotype than resistant (e.g., Svitava). The downregulated was also (Svitava) opposite true for upregulated...
Quinolone synthase from Aegle marmelos (AmQNS) is a type III polyketide that yields therapeutically effective quinolone and acridone compounds. Addressing the structural molecular underpinnings of AmQNS its substrate interaction in terms high selectivity specificity can aid development numerous novel This paper presents high-resolution crystal structure explains mechanistic role synthetic selectivity. Additionally, we provide model framework to comprehend constraints on ketide insertion...
The oestrogenic effect of Glycyrrhiza glabra extract and Pimpinella anisum oil was tested in ovariectomized mice rats by the vaginal smear technique, immature rabbits or uterine weight method. For first procedure animals were injected morning evening 2 consecutive days. Four smears taken: day after last injection, second third after, fourth following day. Smears regarded as positive when epithelial cornification a decrease number leucocytes could be demonstrated. these substances on vagina...
The analysis of Y-chromosome variation has provided valuable clues about the paternal history domestic animal populations. main goal current work was to characterize diversity in 31 goat populations from Central Eastern (Switzerland and Romania) Southern Europe (Spain Italy) as well reference Africa Near East. Towards this end, we have genotyped seven single nucleotide polymorphisms (SNPs), mapping SRY, ZFY, AMELY DDX3Y Y-linked loci, 275 bucks We observed a low level variability...
Ten bacteriophages specific for Bacillus megaterium were isolated from a clay loam soil sample collected the Experimental Farm of Faculty Agriculture, Minia University, Minia, Egypt.Four out ten isolates inactivated after exposure to 80°C 10 min and three at 78°C min.Whereas, other phage 82°C min.The phages found be tolerant wide range pH 5-9.The longevity in vitro varied between isolates.The highest was recorded four (192 h).Electron micrographs indicated that all head tail types.Two...
Toll-like receptors (TLR) are crucial in innate immunity for the recognition of a broad range microbial pathogens and expressed multiple cell types. There 10 TLR genes described pig genome. With twofold objective i.e. to catalogue genetic variants porcine develop genotyping array association studies on immune-related traits, we combined targeted sub-genome enrichment high-throughput sequencing sequence 266 pigs from breeds wild boars using DNA-pooling strategy. We identified 306 single...