A5061393700- Parasites and Host Interactions
- Parasitic Infections and Diagnostics
- Pharmacological Effects and Toxicity Studies
- Amoebic Infections and Treatments
- Parasite Biology and Host Interactions
- Neurological Disorders and Treatments
- Epilepsy research and treatment
- Parkinson's Disease Mechanisms and Treatments
- Malaria Research and Control
- Computational Drug Discovery Methods
- Mosquito-borne diseases and control
- Viral gastroenteritis research and epidemiology
- Cerebrovascular and Carotid Artery Diseases
- Herpesvirus Infections and Treatments
- Chemical synthesis and pharmacological studies
- Hereditary Neurological Disorders
- NF-κB Signaling Pathways
- Menopause: Health Impacts and Treatments
- Neurological Complications and Syndromes
- Multiple Sclerosis Research Studies
- Immune Cell Function and Interaction
- Acute Kidney Injury Research
- Rheumatoid Arthritis Research and Therapies
- Electrolyte and hormonal disorders
- Trigeminal Neuralgia and Treatments
Queen Mary University of London
2023-2025
Beni-Suef University
2013-2024
Taif University
2015-2021
Suez Canal University
2009-2019
Cairo University
2016-2018
Centro Nacional de Microbiologia
2011-2014
Instituto de Salud Carlos III
2011-2014
This study was conducted to assess the effect of carbamazepine, sodium valproate and phenytoin on serum liver enzymes in 49 epileptic patients admitted neurology outpatient clinic at Beni-Suef University between February 2010 June 2011. The were separated into group I (16 patients) treated with 200–1200 mg/day carbamazepine; II 200–800 valproate; III (17 200–400 phenytoin. Serum aspartate aminotransferase (AST), alanine (ALT), alkaline phosphatase (ALP) level antiepileptic drug determined....
Acute ischemic stroke is one of the major causes disability and death worldwide. Effective prevention remains best approach for reducing burden stroke. The aim this work was to study prevalence risk factors possible relation between such disease severity at presentation in a sample patients presented Beni-Suef University Hospital, north Upper Egypt. A 167 acute recruited from Hospital included cross-sectional descriptive study. All subjects were subjected history taking, clinical,...
The Kingdom of Saudi Arabia is seeking malaria eradication. Malaria transmission has been very low over the last few years. Discovered cases Plasmodium falciparum infection are assigned a treatment protocol artemisinin-based combination therapy, which consists artesunate in addition to sulfadoxine-pyrimethamine rather than traditional chloroquine, high resistance rates worldwide. This study aims investigate presence different gene mutations concerning anti-malarial drug (pfdhfr, pfdhps,...
In epilepsy, early diagnosis, accurate determination of epilepsy type, proper selection antiseizure medication, and monitoring are all essential. However, despite recent therapeutic advances conceptual reconsiderations in the classification management serious gaps still encountered day-to-day practice Egypt as well several other resource-limited countries. Premature mortality, poor quality life, socio-economic burden, cognitive problems, treatment outcomes, comorbidities major challenges...
Abstract Background Currently, little is known regarding the association of metabolic comorbidities and disability among multiple sclerosis (MS) patients. Objectives To evaluate insulin resistance (IR) syndrome (MetS) in patients their effect on disease progression disability. Subjects methods This case-control study was conducted 50 MS 25 healthy individuals. They were subjected to clinical evaluation laboratory assessment for resistance. The homeostasis model (HOMA) used as a measurement...
Abstract Introduction Migraine is a common disabling primary headache disorder with significant personal and socio-economic impacts. Medical students usually have multiple triggers for migraine, particularly stress irregular sleep. Objective To assess the prevalence, characteristics, degree of disability migraine in sample Egyptian medical to study their health care-seeking practice when having Patients methods A descriptive cross-sectional, questionnaire-based included 631 undergraduate...
Abstract Background Syntaxin 1A is a member of membrane-integrated nervous system-specific protein superfamily involved in the neuromediator release from synaptic vesicles and one proteins included axonal integrity. Studies that discussed role multiple sclerosis are few limited. Gene studying sometimes shows unexpected results different populations. The aim this work was to investigate genetic polymorphism (rs1569061) sample Egyptian patients with MS relation between gene disease course...
Multiple epidemiological data showed a significant higher prevalence of hypovitaminosis D in patients with Parkinson's disease (PD). To assess the serum vitamin level and to investigate possible relationship between both motor cognitive symptoms A case-control study was conducted on 25 who fulfilled criteria for diagnosis idiopathic based British Brain Bank criteria, healthy volunteers. Selected PD were submitted assessment function using - Cognitive Rating Scale (PD-CRS) Unified Disease...
Abstract Background Copeptin is a new blood biomarker for acute ischemic stroke which emerged to assist clinicians with decision-making. Serum copeptin can accurately reflect vasopressin concentration, plays role in aggravation of inflammatory responses, ions and neurotransmitters dysfunctions. The objective this work was investigate the relation between level as short-term prognosis after 3 months. current study included 45 patients first ever healthy volunteers control. Clinical...
Objective: To assess the relationship between maternal anxiety and depression parent-reported quality of life (QOL) children with cerebral palsy (CP). Methods: A cross-sectional study was done on 232 mothers CP aged 5–18 years. Children QOL mothers' were assessed using Pediatric Inventory Parent Version (PedsQL-P), Beck Anxiety Scale (BAS), Depression (BDI), respectively. Results: Different degrees in 55.5% noted, 47.4% 21.6% had moderate severe anxiety. The mean value PedsQL-P scores 69.35...
Dexmedetomidine provides perioperative cardiac protection in high risk patients assessment the effect of dexmedetomidine undergoing aortic vascular surgery. Arandomized study included 150 classified into two groups(n = 75). Group D: The received a loading dose 1 μg/kg over 15 min before induction and maintained as an infusion 0.3 μg/kg/hr to end procedure. C: equal volume normalsaline. decreased heart rate minimized changes blood pressure compared control group (p < 0.05). Also, it incidence...
Placenta and blood that remained in the umbilical cord is routinely available as a discarded tissue after deliveries it free of any legal, moral, ethical or religious objections, providing high number multipotent CD34(+) progenitor stem cells. Using ex vivo isolated cells from human (hUCB) have emerged promising candidates to treat various diseases, including exogenous pathogenic infections. We expanded build rational approach study effect damaged liver tissues by devastating parasitic...
Schistosoma mansoni infection continues to be one of the most serious parasitosis worldwide due its debilitating effects, mainly hepatic fibrosis. The present study explored antifibrotic effect resveratrol (RSV), either alone or in combination with praziquantel, on murine model intestinal schistosomiasis. We performed two parallel experiments exploring preventive and curative RSV inflammation Parasitological measurements (adult worm burden, oogram), biochemical (AST, ALT, hydroxyproline),...
To evaluate the effect of hemofiltration on lactate level in adult patients undergoing cardiac surgery. Hemofiltration increases level. The study included 283 classified into two groups: group (n = 138), was done during CPB. Control 145), without hemofiltration. elevated H than C (P < 0.05), and PH showed metabolic acidosis 0.05). mixed venous oxygen saturation decreased number transfused packed red blood cells lower hematocrit higher urine output leads to hemoconcentration, increased...