Xinke Zhao

ORCID: 0000-0002-3460-7279
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About
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Research Areas
  • Spectroscopy and Chemometric Analyses
  • Advanced Chemical Sensor Technologies
  • Lung Cancer Diagnosis and Treatment
  • High Altitude and Hypoxia
  • Esophageal and GI Pathology
  • Esophageal Cancer Research and Treatment
  • Traditional Chinese Medicine Analysis
  • COVID-19 Clinical Research Studies
  • Advanced Graph Neural Networks
  • MicroRNA in disease regulation
  • Identification and Quantification in Food
  • Nutrition and Health in Aging
  • Immune cells in cancer
  • Radiomics and Machine Learning in Medical Imaging
  • Iron Metabolism and Disorders
  • Metabolomics and Mass Spectrometry Studies
  • Biochemical effects in animals
  • Pharmacological Effects of Natural Compounds
  • Cardiac, Anesthesia and Surgical Outcomes
  • Water Quality Monitoring and Analysis
  • Phytochemistry and Biological Activities
  • Circular RNAs in diseases
  • Meat and Animal Product Quality
  • Obstructive Sleep Apnea Research
  • SARS-CoV-2 and COVID-19 Research

Gansu University of Traditional Chinese Medicine
2020-2025

Jiangsu University
2023-2024

Weatherford College
2021

Fu Wai Hospital
2021

Chinese Academy of Medical Sciences & Peking Union Medical College
2021

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10.2139/ssrn.5084904 preprint EN 2025-01-01

Myocardial fibrosis (MF) involves the activation and excessive proliferation of cardiac fibroblasts (CFs) in extracellular matrix, leading to increased collagen expression that impairs function. Currently, there are no effective pharmacological treatments for MF. Traditional Chinese Medicine (TCM), particularly Salvia miltiorrhiza Bunge [Lamiaceae; Salviae miltiorrhizae radix et rhizoma], has gained attention its potential treating Recent studies indicate significant therapeutic effects...

10.3389/fphar.2025.1554696 article EN cc-by Frontiers in Pharmacology 2025-03-31

This study aims to investigate the mechanism of ferroptosis mediated by nuclear factor-E2-related factor 2(Nrf2)/solute carrier family 7 member 11(SLC7A11, also known as xCT)/glutathione peroxidase 4(GPX4) signaling pathway in radiationinduced pulmonary fibrosis and intervention effect Angelicae Sinensis Radix(ASR) Astragali Radix(AR) ultrafiltration extract. Fifty Wistar rats were randomly divided into five groups, with 10 each group. Except for blank group without radiation, anesthetized...

10.19540/j.cnki.cjcmm.20240409.402 article EN PubMed 2024-08-01

Ionizing radiation exposure is associated with a risk of cardiac fibrosis; however, the underlying molecular mechanism remains unclear. Growth/differentiation factor-15 (GDF15), fibroblast factor, divergent member transforming growth factor β superfamily. Next-generation sequencing analyses has revealed that Gdf15 increased in fibroblasts during radiation-induced fibrosis. However, role fibrosis In this study, we demonstrated upregulated expression GDF15 newborn rat and adult rats after...

10.1667/rade-20-00206.1 article EN Radiation Research 2021-05-21

This study sought to identify the changes and potential association between sleep characteristics short-term memory, mood states among volunteers at different altitudes times.A total of 26 healthy were recruited from PLA General Hospital, we conducted a longitudinal prospective survey for over 1 year November 2019 April 2021. First, collected demographic data, parameters by overnight polysomnography (PSG), memory digit span test, completing questionnaire with brief profile participants in...

10.3389/fpsyt.2022.952399 article EN cc-by Frontiers in Psychiatry 2022-10-12

Abstract The heavy metal content in edible oils is intricately associated with their suitability for human consumption. In this study, standard soybean oil was used as a sample to quantify the specified concentration of metals using microwave sensing technique. addition, an attention‐based deep residual neural network model developed alternative traditional modeling methods predicting oils. process data processing, work continued discuss impact depth on convolutional networks. results...

10.1111/1750-3841.17259 article EN Journal of Food Science 2024-08-13

Circulating miRNAs presenting in plasma a stable manner have been demonstrated their potential role as promising biomarkers many human diseases, such Alzheimer's disease, melanoma and ovarian carcinoma. However, few circulating could be used for breast ductal cancer diagnosis. Here, we identified miR-1273g-3p biomarker detecting cancer. We detected levels the of 39 sporadic patients 40 healthy donors by Stem-loop Quantitative Real-time PCR (qRT-PCR). The results showed level were...

10.1590/0001-3765202020181203 article EN cc-by Anais da Academia Brasileira de Ciências 2020-01-01

Patients frequently die from cardiac causes after radiotherapy for esophageal cancer. Early detection of death risk in these patients is crucial to improve clinical decision-making and prognosis. Thus, we modeled the irradiation

10.1002/cai2.89 article EN cc-by Cancer Innovation 2023-09-01

This study was designed to evaluate the relationship between polymorphisms in methylenetetrahydrofolate reductase (MTHFR) gene and coronary heart disease (CHD) populations from Gansu region of China. The MTHFR C677T polymorphism genotypes 209 patients with CHD, as confirmed by angiography, 212 non-CHD control were identified using PCR gold magnetic particle chromatography. We simultaneously evaluated homocysteine (Hcy) folate levels these samples biochemical methods. TT genotype locus...

10.1089/dna.2022.0329 article EN DNA and Cell Biology 2022-10-27

To investigate the effects of Luhong Yixin Granules on myocardial fibrosis in rats with heart failure and its possible mechanism, a total 60 male Wistar were randomly divided into control group, model low-, medium-and high-dose groups, 12 each group. Except for those other groups induced by intraperitoneal injection doxorubicin(DOX) rat model. After dissolved same amount normal saline, they given gavage at low, medium high doses(2.8, 5.6, 11.2 g·kg~(-1)·d~(-1)), group saline 40 days. end...

10.19540/j.cnki.cjcmm.20240308.401 article EN PubMed 2024-07-01

This research introduced an innovative application of microwave detection technology to quickly and precisely quantify cadmium concentration in peanut oil. Using the principle free space measurement, a compact device was fabricated, obtain transmission index with frequency range 2.5 GHz 11.5 step size 10MHz. Firstly, preprocessed is selected by using three feature extraction algorithms: competitive adaptive reweighting sampling (CARS) algorithm, boot­strapping soft shrinkage (BOSS)...

10.2139/ssrn.4628490 preprint EN 2023-01-01

"Pneumonia Prevention No.1" belongs to 'traditional Chinese medicine prescription for prevention of viral pneumonia and influenza' was urgently formulated by Notice on Printing the Novel Coronavirus Diagnosis Treatment Scheme COVID-19 (Trial Version 3) Traditional Medicine in Hubei Province (Trial). Because drug has bidirectional regulation function human immune function, moderate improvement can effectively resist virus invasion, while excessive will produce overresponse. Excessive response...

10.2147/idr.s377974 article EN cc-by-nc Infection and Drug Resistance 2022-11-01
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