A5100641516- Hemoglobinopathies and Related Disorders
- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Sperm and Testicular Function
- Hepatitis B Virus Studies
- Mental Health Treatment and Access
- Cervical Cancer and HPV Research
- Medical Research and Treatments
- Healthcare and Venom Research
- Iron Metabolism and Disorders
- Blood groups and transfusion
- Hepatitis C virus research
- Substance Abuse Treatment and Outcomes
- Thyroid Cancer Diagnosis and Treatment
- Animal Virus Infections Studies
- Acute Ischemic Stroke Management
- Prenatal Screening and Diagnostics
- Adolescent Sexual and Reproductive Health
- Ethics in medical practice
- Parvovirus B19 Infection Studies
- Venous Thromboembolism Diagnosis and Management
- Microbial infections and disease research
- Radiomics and Machine Learning in Medical Imaging
- Innovations in Medical Education
- Cannabis and Cannabinoid Research
University of Pittsburgh
2014-2025
University of Electronic Science and Technology of China
2023-2025
Zhongnan Hospital of Wuhan University
2019-2025
Wuhan University
2011-2025
Heilongjiang University of Chinese Medicine
2023-2025
Shenyang Pharmaceutical University
2016-2025
Xi'an Jiaotong University
2013-2024
Tianjin University of Traditional Chinese Medicine
2023-2024
Xiangya Hospital Central South University
2022-2024
South China University of Technology
2020-2024
Defective autophagy in Alzheimer's disease (AD) promotes progression diverse ways. Here, we demonstrate impaired flux primary glial cells derived from CRND8 mice that overexpress mutant amyloid precursor protein (APP). Functionalized single-walled carbon nanotubes (SWNT) restored normal by reversing abnormal activation of mTOR signaling and deficits lysosomal proteolysis, thereby facilitating elimination autophagic substrates. These findings suggest SWNT as a novel neuroprotective approach...
Prediction of high-risk events amongst patients with mental disorders is critical for personalized interventions. We developed DeepBiomarker2 by leveraging deep learning and natural language processing to analyze lab tests, medication use, diagnosis, social determinants health (SDoH) parameters, psychotherapy outcome prediction. To increase the model’s interpretability, we further refined our contribution analysis identify key features scaling a factor from reference feature. applied EMR...
Near-infrared II (NIR-II) imaging and photothermal therapy hold tremendous potential in precision diagnosis treatment within biological organisms. However, a significant challenge is the shortage of NIR-II fluorescent probes with both high conversion coefficient (PCE) fluorescence quantum yield (Φ
Identifying co-occurring mental disorders and elevated risk is vital for optimization of healthcare processes. In this study, we will use DeepBiomarker2, an updated version our deep learning model to predict the adverse events among patients with comorbid post-traumatic stress disorder (PTSD) alcohol (AUD), a high-risk population.
Introduction Post-Traumatic Stress Disorder (PTSD) entails behavioral changes with increased risk of suicide, and there is no consensus on the preferred antidepressants for treatment those PTSD patients who are at elevated suicide. Methods We conducted a clinical trial emulation study comparing suicide-related events (SREs) among patients’ initiating within 60 days after qualifying SRE. Patients were followed from initiation antidepressant until any following: cessation, switching, death, or...
Natural variations are the basis of crop improvement. However, genomic variability remains largely understudied. We present full-spectrum integrated panvariome and pangenome 1,020 peach accessions, including 10.5 million SNPs, indels, DELs, INSs, DUPs, INVs, TRAs, CNVs, TIPs, PAVs, uncovering 70.6% novel variants 3,289 genes. Analysis reconstructs globally evolutionary history identifies several trait-causally rare variants, improving power breeding markers. Landraces improved accessions...
Background The length of stay (LOS) patients with schizophrenia has been a wide concern researchers. Reasonable management the LOS to achieve balance between quality treatment and efficient medical source allocation become significant issue in clinical work psychiatry. Figuring out factors related can help optimize its by hospital. Method essential information was obtained from electronic record system. variables were divided into following kinds: demographic, clinical, biochemical....
Myocardial fibrosis can induce cardiac dysfunction and remodeling. Great attention has been paid to Traditional Chinese Medicine (TCM) 's effectiveness in treating MF. Radix Angelica sinensis (Oliv.) Diels Astragalus mongholicus Bunge ultrafiltration extract (RAS-RA), which is a key TCM compound preparation, have high efficacy regulating inflammation. However, studies on its therapeutic effect radiation-induced myocardial (RIMF) are rare. In this study, RAS-RA had RIMF elucidated mechanism...
Abstract Researchers conducted a study in Taiwanese medical center from June 2009 to 2011 investigate the relations of perceived stress and lifestyle breast cancer. A total 157 cases 314 controls completed structured questionnaire. Using multiple logistic regression models, high (adjusted odds ratio [AOR] = 1.65; 95% confidence interval [CI], 1.10–2.47), less than 1,000 kcal physical activity expenditure per week (AOR, 2.17; CI, 1.39–3.39), intake fried stir-fried food 1.86; 1.24–2.77) were...
Whether Hashimoto's thyroiditis (HT) affects the lymph node metastasis of papillary thyroid carcinoma (PTC) remains uncertain. The diagnostic criteria for HT differed in previous studies. Our study focused on analysing influence PTC (LNM) with stringent HT.A total 444 patients diagnosed from 2019 to 2020 were enrolled and divided into two groups: group non-HT group. Diagnostic as follows: peroxidase antibody (+) postoperative histopathology disease.There was no significant difference LNM...