A5022507636- Anesthesia and Neurotoxicity Research
- Cardiac, Anesthesia and Surgical Outcomes
- Pediatric Pain Management Techniques
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Pain Management
- Radiomics and Machine Learning in Medical Imaging
- Colorectal Cancer Screening and Detection
- Nausea and vomiting management
- S100 Proteins and Annexins
- Anesthesia and Sedative Agents
- Cardiac Ischemia and Reperfusion
- Colorectal Cancer Surgical Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Inflammatory Biomarkers in Disease Prognosis
- Cancer Immunotherapy and Biomarkers
First Affiliated Hospital of Zhengzhou University
2015-2022
Abstract The aim of this study is to explore the feasibility using machine learning (ML) technology predict postoperative recurrence risk among stage IV colorectal cancer patients. Four basic ML algorithms were used for prediction—logistic regression, decision tree, GradientBoosting and lightGBM. research samples randomly divided into a training group testing at ratio 8:2. 999 patients with 4 included in study. In group, model’s AUC value was highest, 0.881. Logistic lowest, 0.734. model had...
To use machine learning algorithms to predict the death outcomes of patients with triple-negative breast cancer, 5 years after discharge.1570 stage I-III cancer receiving treatment from Sun Yat-sen Memorial Hospital were analyzed. Machine was used discharge.The results showed that platelets, LMR (lymphocyte-to-monocyte ratio), age, PLR (the platelet-to-lymphocyte ratio) and white blood cell counts accounted for a significant weight in 5-year prognosis patients. The model prediction indicated...
Introduction This study examined the protective effects of sophoricoside on neuronal injury and cognitive dysfunction in anaesthetic-exposed neonatal rats. Material methods Neuronal was induced rat pups by exposure to isoflurane (0.75%) with 30% oxygen for 6 h P7. The were evaluated assessing function using neurological score Morris water maze. apoptosis assessed hippocampus tissue a TUNEL assay. cytokine macrophage inflammatory protein levels ELISA. Western blot assays RT-PCR performed...
Objective To evaluate the effect of dexmedetomidine on cognitive dysfunction after thoracic surgery in patients undergoing one-lung ventilation. Methods Sixty-two patients, aged 45-64 yr, ASA physical status Ⅰ or Ⅱ, with body mass index ranged from 17.5 to 25.5 kg/m2, scheduled for elective surgery, were randomly allocated into 2 groups(n=31 each)using a random number table: group(Dex group)and control group(C group). Dexmedetomidine 0.5 μg/kg was infused 10 min starting time point...
Objective To investigate the effect of Dexmedetomidine (Dex) on long-term cognitive function after extracapsular lens extraction (ECLE) in mice. Methods Forty adult male C57BL/6J mice were randomly divided into control group (C group), ECLE group, normal saline (NS group) and Dex with 10 each group. Three days model was made, mouse C underwent Morris water maze test, then they euthanized hippocampus tissue immediately excised for determination wet weight to dry (W/D) total content...