A5022075647- Atomic and Subatomic Physics Research
- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Magnetic and transport properties of perovskites and related materials
- Optical Imaging and Spectroscopy Techniques
- Music Therapy and Health
- Art Therapy and Mental Health
- Quantum optics and atomic interactions
- Visual perception and processing mechanisms
- Non-Invasive Vital Sign Monitoring
- Psychotherapy Techniques and Applications
Dantec Dynamics (United Kingdom)
2025
University of Nottingham
2019-2024
Hospital for Sick Children
2023
SickKids Foundation
2023
Great Ormond Street Hospital
2023
University College London
2023
Purdue University West Lafayette
2019
Magnetoencephalography (MEG) is a powerful technique for functional neuroimaging, offering non-invasive window on brain electrophysiology. MEG systems have traditionally been based cryogenic sensors which detect the small extracranial magnetic fields generated by synchronised current in neuronal assemblies, however, such fundamental limitations. In recent years, non-cryogenic quantum-enabled sensors, called optically-pumped magnetometers (OPMs), combination with novel techniques accurate...
Optically-pumped magnetometers (OPMs) are an established alternative to superconducting sensors for magnetoencephalography (MEG), offering significant advantages including flexibility accommodate any head size, uniform coverage, free movement during scanning, better data quality and lower cost. However, OPM sensor technology remains under development; there is regarding design it not yet clear which variant will prove most effective MEG. Most OPM-MEG implementations have either used...
The optically pumped magnetometer (OPM) is a viable means to detect magnetic fields generated by human brain activity. Compared conventional detectors (superconducting quantum interference devices) OPMs are small, lightweight, flexible, and operate without cryogenics. This has led step change in instrumentation for magnetoencephalography (MEG), enabling "wearable" scanner platform, adaptable fit any head size, able acquire data whilst subjects move, offering improved quality. Although many...
Optically-pumped magnetometers (OPMs) offer the potential for a step change in magnetoencephalography (MEG) enabling wearable systems that provide improved data quality, accommodate any subject group, allow capture during movement and potentially reduce cost. However, OPM-MEG is nascent technology and, to realise its potential, it must be shown facilitate key neuroscientific measurements, such as characterisation of brain networks. Networks, connectivities underlie them, have become core...
Optically pumped magnetometers (OPMs) are an emerging lightweight and compact sensor that can measure magnetic fields generated by the human brain. OPMs enable construction of wearable magnetoencephalography (MEG) systems, which offer advantages over conventional instrumentation. However, when trying to signals at low frequency, higher levels inherent noise, interference movement artefact introduce a significant challenge. Accurate characterisation frequency brain is important for...
Optically-pumped magnetometers (OPMs) are highly sensitive, compact magnetic field sensors, which offer a viable alternative to cryogenic sensors (superconducting quantum interference devices – SQUIDs) for magnetoencephalography (MEG). With the promise of wearable system that offers lifespan compliance, enables movement during scanning, and provides higher quality data, OPMs could drive step change in MEG instrumentation. However, this potential can only be realised if background fields...
Magnetically shielded rooms (MSRs) use multiple layers of materials such as MuMetal to screen external magnetic fields that would otherwise interfere with high precision field measurements magnetoencephalography (MEG). Optically pumped magnetometers (OPMs) have enabled the development wearable MEG systems which potential provide a motion tolerant functional brain imaging system spatiotemporal resolution. Despite significant promise, OPMs impose stringent shielding requirements, operating...
Magnetoencephalography (MEG) measures the small magnetic fields generated by current flow in neural networks, providing a noninvasive metric of brain function. MEG is well established as powerful neuroscientific and clinical tool. However, instrumentation hampered cumbersome cryogenic field-sensing technologies. In contrast, using optically pumped magnetometers (OPM-MEG) employs small, lightweight, noncryogenic sensors that provide data with higher sensitivity spatial resolution, natural...
The ability to collect high-quality neuroimaging data during ambulatory participant movement would enable a wealth of neuroscientific paradigms. Wearable magnetoencephalography (MEG) based on optically pumped magnetometers (OPMs) has the potential allow scan. However, strict zero magnetic field requirement OPMs means that systems must be operated inside magnetically shielded room (MSR) and also require active shielding using electromagnetic coils cancel residual fields changes (due external...
The evolution of human cognitive function is reliant on complex social interactions which form the behavioural foundation who we are. These capacities are subject to dramatic change in disease and injury; yet their supporting neural substrates remain poorly understood. Hyperscanning employs functional neuroimaging simultaneously assess brain activity two individuals offers best means understand basis interaction. However, present technologies limited, either by poor performance (low...
Abstract Optically pumped magnetometers (OPMs) offer a new wearable means to measure magnetoencephalography (MEG) signals, with many advantages compared conventional systems. However, OPMs are an emerging technology, thus characterizing and replicating MEG recordings is essential. Using OPM-MEG SQUID-MEG, this study investigated evoked responses, oscillatory power, functional connectivity during emotion processing in 20 adults, establish replicability across the two technologies. Five...
Abstract Magnetoencephalography (MEG) measures brain function via assessment of magnetic fields generated by neural currents. Conventional MEG uses superconducting sensors, which place significant limitations on performance, practicality, and deployment; however, the field has been revolutionised in recent years introduction optically-pumped magnetometers (OPMs). OPMs enable measurement signal without cryogenics, consequently conception “OPM-MEG” systems ostensibly allow increased...
Optically pumped magnetometers (OPMs) have made moving, wearable magnetoencephalography (MEG) possible. The OPMs typically used for MEG require a low background magnetic field to operate, which is achieved using both passive and active shielding. However, the never truly zero Tesla, so at each of changes as participant moves. This leads position orientation dependent in measurements, manifest frequency artefacts data.
Non-invasive imaging has transformed neuroscientific discovery and clinical practice, providing a non-invasive window into the human brain. However, whilst techniques like MRI generate ever more precise images of brain structure, in many cases, it's function within neural networks that underlies disease. Here, we review potential for quantum-enabled magnetic field sensors to shed light on such activity. Specifically, describe how optically pumped magnetometers (OPMs) enable...
Abstract Electroencephalography (EEG) and magnetoencephalography (MEG) non-invasively measure human brain electrophysiology. They differ in nature; MEG offers better performance while EEG (a wearable platform) is more practical. are also complementary, with studies showing that concurrent MEG/EEG provides advantages over either modality alone, consequently clinical guidelines for epilepsy recommend simultaneous acquisition of EEG. In recent years, new instrumentation—the optically pumped...
Abstract Disruption of the balance between excitatory and inhibitory neurotransmission (E-I balance) is thought to underlie many neurodevelopmental disorders; however, its study typically restricted adults, animal models lab-bench. Neurophysiological oscillations in gamma frequency band relate closely E-I balance, a new technology – OPM-MEG offers possibility measure such signals across lifespan. We used induced by visual stimulation 101 participants, aged 2-34 years. demonstrate...
Abstract Background Brain-computer interfaces decode intentions directly from the human brain with aim to restore lost functionality, control external devices or augment daily experiences. To combine optimal performance wide applicability, high-quality signals should be captured non-invasively. Magnetoencephalography (MEG) is a potent candidate but currently requires costly and confining recording hardware. The recently developed optically pumped magnetometers (OPMs) promise overcome this...
ABSTRACT Magnetoencephalography (MEG) measures brain function via assessment of magnetic fields generated by neural currents. Conventional MEG uses superconducting sensors, which place significant limitations on performance, practicality, and deployment; however, the field has been revolutionised in recent years introduction optically-pumped-magnetometers (OPMs). OPMs enable measurement signal without cryogenics, consequently conception ‘OPM-MEG’ systems ostensibly allow increased...
Abstract Background Optically pumped magnetometers (OPMs) have made moving, wearable magnetoencephalography (MEG) possible. The OPMs typically used for MEG require a low background magnetic field to operate, which is achieved using both passive and active shielding. However, the never truly zero Tesla, so at each of changes as participant moves. This leads position orientation dependent in measurements, manifest frequency artefacts data. Objective We modelled spatial variation model predict...
Abstract The evolution of human cognitive function is reliant on complex social interactions which form the behavioural foundation who we are. These capacities are subject to dramatic change in disease and injury; yet their supporting neural substrates remain poorly understood. Hyperscanning employs functional neuroimaging simultaneously assess brain activity two individuals offers best means understand basis interaction. However, present technologies limited, either by poor performance (low...
ABSTRACT Electroencephalography (EEG) and magnetoencephalography (MEG) non-invasively measure human brain electrophysiology. They differ in nature; MEG offers better performance (higher spatial precision) whilst EEG (a wearable platform) is more practical. are also complementary, with studies showing that concurrent MEG/EEG provides advantages over either modality alone, consequently clinical guidelines for epilepsy recommend simultaneous acquisition of EEG. In recent years, new...
Optically pumped magnetometers (OPMs) are becoming common in the realm of biomagnetic measurements. We discuss development a prototype zero-field cesium portable OPM and its miniaturized components. Zero-field sensors operate very low static magnetic field environment exploit physical effects this regime. OPMs type extremely sensitive to small fields, but they bring specific challenges component design, material choice, current routing. The atomic vapor cell within sensor has been produced...
ABSTRACT Magnetoencephalography (MEG) is a powerful technique for functional neuroimaging, offering non-invasive window on brain electrophysiology. MEG systems have traditionally been based cryogenic sensors which detect the small extracranial magnetic fields generated by synchronised current in neuronal assemblies, however such fundamental limitations. In recent years quantum-enabled devices, called optically-pumped magnetometers (OPMs), promised to lift those restrictions, an adaptable,...