- MicroRNA in disease regulation
- Neurogenesis and neuroplasticity mechanisms
- Dermatology and Skin Diseases
- Essential Oils and Antimicrobial Activity
- Cellular Mechanics and Interactions
- Hops Chemistry and Applications
- Antimicrobial Peptides and Activities
- 3D Printing in Biomedical Research
- Microfluidic and Bio-sensing Technologies
- Circular RNAs in diseases
- RNA Research and Splicing
- Stress Responses and Cortisol
Monasterium Laboratory Skin & Hair Research Solutions (Germany)
2023
Sapienza University of Rome
2013-2017
Max Planck Institute for Molecular Biomedicine
2016
The amygdala is a brain structure considered key node for the regulation of neuroendocrine stress response. Stress-induced response in accomplished through neurotransmitter activation and an alteration gene expression. MicroRNAs (miRNAs) are important regulators expression nervous system very well suited effectors their ability to reversibly silence specific mRNAs. In order study how acute affects miRNAs we analyzed miRNA profile after two hours mouse restraint, by microarray analysis...
Abstract The precise positioning of organ progenitor cells constitutes an essential, yet poorly understood step during organogenesis. Using primordial germ that participate in gonad formation, we present the developmental mechanisms maintaining a motile cell population at site where develops. Employing high-resolution live-cell microscopy, find repulsive cues coupled with physical barriers confine to correct bilateral positions. This analysis revealed polarity changes on interaction barrier...
Introduction: Several olfactory receptors (ORs) are expressed in human skin, where they regulate skin pigmentation, barrier function, wound healing, and hair growth. Previously, we found that the selective activation of OR family 2 subfamily AT member 4 (OR2AT4) by synthetic, sandalwood-like odorant Sandalore® differentially stimulates expression antimicrobial peptides (AMPs) scalp follicle epithelium ex vivo. As OR2AT4 is also epidermal keratinocytes, hypothesized it may modulate...