A5016604340- Adipokines, Inflammation, and Metabolic Diseases
- Atherosclerosis and Cardiovascular Diseases
- Obstructive Sleep Apnea Research
- Gout, Hyperuricemia, Uric Acid
- Cardiovascular and Diving-Related Complications
- Autophagy in Disease and Therapy
- Takotsubo Cardiomyopathy and Associated Phenomena
- interferon and immune responses
- Alcohol Consumption and Health Effects
- T-cell and B-cell Immunology
- RNA Research and Splicing
- Caveolin-1 and cellular processes
- Single-cell and spatial transcriptomics
- RNA Interference and Gene Delivery
- Inflammatory Biomarkers in Disease Prognosis
- Long-Term Effects of COVID-19
- Neurological Complications and Syndromes
- Systemic Lupus Erythematosus Research
- RNA regulation and disease
- SARS-CoV-2 and COVID-19 Research
- Cardiovascular Disease and Adiposity
- Cell Adhesion Molecules Research
- Spinal Cord Injury Research
- Liver Disease Diagnosis and Treatment
- Metabolism, Diabetes, and Cancer
Shanxi Medical University
2008-2024
Second Hospital of Shanxi Medical University
2008-2024
Thomas Jefferson University
2014
Background Non-alcoholic fatty liver disease (NAFLD) is independently associated with atrial fibrillation (AF) risk. The uric acid (UA) to high-density lipoprotein cholesterol (HDL-C) ratio (UHR) has been shown be closely cardiovascular (CVD) and NAFLD. aim of this study clarify whether elevated UHR the occurrence AF in patients NAFLD determine predicted AF. Methods Patients diagnosed Department Cardiovascular Medicine Second Hospital Shanxi Medical University from January 1, 2020, December...
Platelet activation is important in hypertension‑induced cardiac inflammation and fibrosis. P-selectin expression significantly (P<0.05) increases when platelets are activated during hypertension. Although P‑selectin recruits leukocytes to sites of inflammation, the role fibrosis remains be elucidated. The present study aimed investigate whether platelet‑derived promotes hypertensive knockout (P‑sel KO) mice wild‑type (WT) C57BL/6 littermates were infused with angiotensin II (Ang II) at...
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has rapidly become a global health emergency. In addition to causing effects, SARS-CoV-2 can result in cardiac involvement leading myocardial damage, which is increasingly being explored the literature. Myocardial injury an important pathogenic feature of COVID-19. The angiotensin-converting enzyme-2 receptor plays key role pathogenesis virus, serving as “bridge” allowing invade body....
Obstructive sleep apnea (OSA) affects the occurrence of atrial fibrillation (AF) and usually coexists with AF. Chronic inflammation has been identified as an important factor in development AF, neutrophil-to-lymphocyte ratio (NLR) a biomarker that positively correlates degree inflammation. However, little information regarding how NLR AF OSA patients.Our study enrolled 368 patients between September 2018 April 2023. All data were collected after admission. Independently associated factors...
The purpose of the present study was to investigate effects on blood pressure and myocardial hypertrophy in SHRs (spontaneously hypertensive rats) RNAi (RNA interference) targeting ACE (angiotensin-converting enzyme). were treated with normal saline as vehicle controls, Ad5-EGFP vector recombinant adenoviral vectors Ad5-EGFP-ACE-shRNA, carrying shRNA (small hairpin RNA) for ACE-RNAi. WKY (Wistar-Kyoto) rats used normotensive controls saline. systolic caudal artery recorded. Serum levels...
Immune and inflammatory responses have a pivotal role in the pathogenesis of rheumatoid arthritis (RA) atherosclerotic cardiovascular disease (ASCVD). This study aims to explore change peripheral lymphocytes, especially absolute relative changes T cells RA patients with without ASCVD.The lymphocyte subsets were assessed provide novel insight diagnosing preventing ASCVD RA.A propensity score matching system (1:1) was conducted perform matched case-control 169 pairs RA-ASCVD participants....
Abstract Cholesterol efflux from foam cells in atherosclerotic plaques is crucial for reverse cholesterol transport (RCT), an important antiatherogenic event. ATP-binding cassette (ABC) transporters, ABCA1 and ABCG1, are key receptors the pathway. C1q/tumor necrosis factor-related protein-9 (CTRP9) a newly discovered adipokine exhibits atheroprotective activity. However, role of CTRP9 RCT still remains unknown. In this work, we investigated effect subcutaneous administration protein on...
Spontaneous coronary artery dissection (SCAD) is a rare cause of acute syndrome in young persons, rarely found men.There are currently no known direct causes this condition, although some correlations have been found.We report the case 45-year-old man with unstable angina pectoris secondary to spontaneous diffuse spiral right artery.In addition, patient was diagnosed other autoimmune related diseases, for example hypothyroidism, chronic atrophic gastritis, lung emphysema, which suggesting...