A5090395664- Cardiovascular Health and Disease Prevention
- Blood Pressure and Hypertension Studies
- Atrial Fibrillation Management and Outcomes
- Coronary Interventions and Diagnostics
- Heart Failure Treatment and Management
- Cardiac Arrhythmias and Treatments
- Stroke Rehabilitation and Recovery
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Liver Disease Diagnosis and Treatment
- Heart Rate Variability and Autonomic Control
- Acute Myocardial Infarction Research
- Acute Kidney Injury Research
- Cardiovascular and exercise physiology
- Neurological Disorders and Treatments
- EEG and Brain-Computer Interfaces
- Cardiovascular Disease and Adiposity
- Botulinum Toxin and Related Neurological Disorders
- Adipokines, Inflammation, and Metabolic Diseases
- Neonatal Respiratory Health Research
- Cerebrovascular and Carotid Artery Diseases
- Mechanical Circulatory Support Devices
- RNA modifications and cancer
- ECG Monitoring and Analysis
- Antiplatelet Therapy and Cardiovascular Diseases
Shanghai Ninth People's Hospital
2019-2025
Shanghai Jiao Tong University
2010-2025
Tengzhou Central People's Hospital
2025
Jining Medical University
2025
First Affiliated Hospital of Zhengzhou University
2025
Shanghai East Hospital
2019-2024
Second Hospital of Shandong University
2015-2024
University of Hong Kong
2024
Guangzhou Medical University
2020-2024
Chinese University of Hong Kong
2020-2024
Abstract Mouse cortical radial glial cells (RGCs) are primary neural stem that give rise to oligodendrocytes, astrocytes, and olfactory bulb (OB) GABAergic interneurons in late embryogenesis. There fundamental gaps understanding how these diverse cell subtypes generated. Here, by combining single-cell RNA-Seq with intersectional lineage analyses, we show beginning at around E16.5, neocortical RGCs start generate ASCL1 + EGFR apical multipotent intermediate progenitors (MIPCs), which then...
Abstract Aim Patients with diabetes mellitus have poor prognosis after myocardial ischemic injury. However, the mechanism is unclear and there are no related therapies. We aimed to identify regulators of diabetic Methods results Mass spectrometry-based, non-targeted metabolomic approach was used profile coronary sinus blood from non-diabetic Bama-mini pigs at 0.5-h post artery ligation. Six metabolites had a |log 2 (Fold Change)|> 1.3. Among them, most changed arachidonic acid (AA),...
Journal Article Accepted manuscript Real-time monitoring of postfilter calcium in regional citrate anticoagulation for continuous kidney replacement therapy Get access Zhang Qi, Qi Department Nephrology, Shanghai Ninth People's Hospital, School Medicine, Jiao Tong University, Shanghai, China Search other works by this author on: Oxford Academic PubMed Google Scholar Beiyi, Beiyi Physics and Astronomy, Yue Zengqi, Zengqi Sun Chen, Chen Yu Jin, Jin Correspondence to: Jin; E-mail: [email...
Gallstones (GS), a prevalent disorder of the biliary tract, markedly impair patients' quality life. This study aims to construct predictive models employing diverse machine learning algorithms elucidate risk factors linked gallstone formation. integrated data from National Health and Nutrition Examination Survey (NHANES) with cohort 7868 participants Wuxi People's Hospital Second Hospital, including 830 individuals diagnosed gallstones. To develop our model, we employed four...
To explore the pain prognosis, medication efficacy and treatment willingness of patients with burning mouth syndrome (BMS) to identify factors influencing BMS. Medical records who were clinically diagnosed BMS complained oral mucosal at Department Stomatology, The First Affiliated Hospital Zhengzhou University, retrospectively collected from January 2019 April 2022. Telephone follow-ups conducted in August 2024 investigate patients' efficacy, for related information. Among 192 patients, only...
A positive association between hypertension or high-normal blood pressure (BP) and risk of nonalcoholic fatty liver disease (NAFLD) is well-known; however, no data have been generated exploring the NAFLD within normal range BP. We aimed to assess systolic (SBP) NAFLD. total 27,769 subjects from 2 separate medical centers were included. Subjects divided into 4 groups (G1 G4) by SBP levels: G1: 90–99 mmHg, G2: 100–109 G3: 110–119 G4: 120–129 mmHg. The prevalence, hazard ratios (HRs) 95%...
Background Non-alcoholic fatty liver disease (NAFLD) is independently associated with atrial fibrillation (AF) risk. The uric acid (UA) to high-density lipoprotein cholesterol (HDL-C) ratio (UHR) has been shown be closely cardiovascular (CVD) and NAFLD. aim of this study clarify whether elevated UHR the occurrence AF in patients NAFLD determine predicted AF. Methods Patients diagnosed Department Cardiovascular Medicine Second Hospital Shanxi Medical University from January 1, 2020, December...
To investigate whether glycation level of apoprotein (apo)A-I is associated with coronary artery disease (CAD) and plaque progression in patients type 2 diabetes.Among 375 consecutive diabetic undergoing quantitative angiography (QCA) intravascular ultrasound (IVUS), 82 nonsignificant stenosis (luminal diameter narrowing <30% [group I]) 190 significant CAD ≥70% II]) were included for analysis apoA-I serum activity lecithin: cholesterol acyltransferase (LCAT). The control group had 136...
A high red blood cell distribution width (RDW) at admission or discharge is associated with a worse prognosis in hospitalized patients heart failure (HF), and the prognostic value of in-hospital change RDW (∆RDW) remains debatable.We included 5514 critical illness HF from MIMIC-IV database. The ΔRDW was calculated by minus that admission. Clinical outcomes all-cause mortality 90 day, 180 1 year after discharge. median age 73.91 years, 46.37% were women. Kaplan-Meier curve Cox regression...
OBJECTIVE:To evaluate the feasibility of vector flow imaging technique (V Flow) in measurement wall shear stress (WSS) common carotid arteries (CCA) healthy adults and to provide normal WSS values assessed by V Flow. METHODS & MATERIALS:This prospective study was approved Ethics Committee our University. Eighty adult volunteers were included (mean age 43.3 y, 47 females, 33 males). The classified into three groups according their age: group I (age 20 - 39 y), II 40 59 y) III 60 80 y)....
ABSTRACT Background In recent years, the incidence of wasp sting has increased annually in China. Organ damage and high mortality due to mass envenomation remain major challenges. Timely appropriate medical intervention can improve survival. However, there are currently no normalized tools for early assessment severity. Methods The clinical data patients hospitalized from 2011 2019 were used as a training set. Logistic regression was explore risk factors development severe case (SC). Wasp...
Background The pathophysiological process of calcific aortic valve disease (CAVD) is similar to that atherosclerosis. Leptin accelerates the We sought examine relationship between leptin and CAVD. Methods Results Serum was measured in 397 consecutive patients undergoing standard transthoracic echocardiography Doppler flow imaging. Multiple logistic regression analyses were used assess association Western blotting performed detect expression phosphorylated total extracellular signal-regulated...
The mammillary body is a hypothalamic nucleus that has important functions in memory and spatial navigation, but its developmental principles remain not well understood. Here, we identify progenitor-specific Fezf2 expression the developing develop an intersectional fate-mapping approach to demonstrate Fezf2+ progenitors generate neurons rostral-dorsal-lateral caudal-ventral-medial fashion. Axonal tracing from different temporal cohorts of labeled reveal their topographical organization....
Abstract Background There are emerging clinical evidence for umbilical cord blood mononuclear cells (UCBMNCs) intervention to improve preterm complications. The first critical step in cell therapy is obtain high-quality cells. This retrospective study aimed investigate the quantity and quality of UCBMNCs from very infants (VPIs) purpose autologous prevention treatment Methods Very born Guangdong Women Children Hospital January 1, 2017, December 8, 2022, whom was successfully collected...
Background Dysnatremia is the most common electrolyte disorder in hospitalized patients. Sodium fluctuation level may be a better parameter dysnatremia management. We aimed to examine association between sodium during hospitalization and mortality evaluate its value predicting poor prognosis among general Methods Data were collected from patients admitted Peking Union Medical College Hospital. The generalized estimated equation (GEE) was used relationship mortality. Receiver-operating...
Although auditory stimuli benefit patients with disorders of consciousness (DOC), the optimal stimulus remains unclear. We explored most effective electroencephalography (EEG)-tracking method for eliciting brain responses to and assessed its potential as a neural marker improve DOC diagnosis. collected 58 EEG recordings from evaluate classification model's performance stimulus. Using non-linear dynamic analysis (approximate entropy [ApEn]), we various (resting state, preferred music,...
Six-minute walk test (6MWT) continues to be a useful tool determine the functional capacity in patients with vascular and other lung diseases; nevertheless, it has limited ability predict prognosis this context. We tested whether heart rate (HR) acceleration decay slopes during 6-m are different pulmonary arterial hypertension (PAH), diseases, healthy controls. In addition, we assessed HR associated clinical worsening. Using portable, signal-morphology-based, impedance cardiograph...