- Sesquiterpenes and Asteraceae Studies
- Natural product bioactivities and synthesis
- Plant Toxicity and Pharmacological Properties
- Phytochemistry and Biological Activities
- Toxin Mechanisms and Immunotoxins
- Biological Activity of Diterpenoids and Biflavonoids
- Medicinal plant effects and applications
- Traditional and Medicinal Uses of Annonaceae
- Herbal Medicine Research Studies
- Medicinal Plant Extracts Effects
- Marine Sponges and Natural Products
- Essential Oils and Antimicrobial Activity
- Cynara cardunculus studies
- Synthetic Organic Chemistry Methods
- Insect Pheromone Research and Control
- Skin Protection and Aging
- Plant Ecology and Taxonomy Studies
- Pharmacological Effects of Natural Compounds
- Medicinal Plants and Bioactive Compounds
- X-ray Diffraction in Crystallography
- Insect Pest Control Strategies
- Crystallization and Solubility Studies
- Bee Products Chemical Analysis
- Phytochemical compounds biological activities
- Natural Compounds in Disease Treatment
Medicina
1984-2025
Pomeranian Medical University
2023-2024
Poznan University of Medical Sciences
2010-2023
National Veterinary Research Institute
2004
National Institute on Drug Abuse
1994
Adam Mickiewicz University in Poznań
1993
New York Academy of Medicine
1993
Institute of Organic Chemistry
1992
Polish Academy of Sciences
1992
The authors would like to make the following correction published paper [...]
Summary Background Arbutin is one of the most effective lightening substances. Serratula quinquefolia a new source its β ‐anomer. The HPLC method showed that solid content this compound in dried plant raw material accounts for 6.86%. leaves do not contain hydroquinone. Aims To assess efficacy aqueous extract from' leaf five‐leaf serratula as skin‐lightening agent. Patients/Methods We did randomized, placebo‐controlled, double‐blind trial. study involved 102 women aged 26–55, with two kinds...
The milky juice of the greater celandine herb has been used in folk medicine and homeopathy for treatment viral warts years. However, classical fails to use properties herbs diseases induced by papilloma viruses. Nevertheless, dermatological outpatient clinics are regularly visited patients reporting efficacy sap isolated from their own warts. Authors this report decided analyze respective world literature order critically evaluate potential dermal using celandine. Moreover, case a 4-year...
This paper presents raw plant materials and their characteristic compounds which may affect the immune system. Plant-derived agents in specific doses body’s non-specific, antigen-independent defense They have immunostimulatory effects on entire regulatory can enhance response through various factors such as macrophages, leukocytes, granulocytes, well mediators released by cellular was inspired threats caused COVID-19 pandemic. The proper functioning of system is important limiting viral...
The occurrence of both known and new sesquiterpene lactones was determined in six species classified different subgenera <em>Centaurea L. </em>Chlorojanerin, cynaropicrin janerin were isolated from <em>C. phaeopappoides </em>Bordz. thracica </em>(Janka) Hayek. marschalliana </em>Spreng. found to contain acroptilin, chlorojanerin, cebellin D while adjarica </em>Alb. had repin, centaurepensin, janerin, repidiolide, D, E, F L A new, hitherto...
Cnicin was isolated from 18 species or subspecies of the subgenus <em>Acrolophus</em> (Cass.) Dobrocz.: <em>Centaurea aplolepa</em> Moretti subsp. <em>aplolepa</em>, <em>C. <em>lunensis</em> (Fiori) Dostal, arenaria</em> Bieb. ex Wild. <em>arenaria, C. Wild, <em>odessana</em> (Prodan) Bieb <em>majorowii</em> (Dumbadze) calvescens</em> Pančić, cineraria</em> L. <em>cineraria, var,...
Guaianolides were found in three species of the genus <em>Leuzea</em> DC. Chlorojanerin, cynaropicrin and janerin isolated from <em>L. rhapontica</em> subg. <em>helenifolia</em> (Gren, Gordon) Holub rhaponticoides</em> Graells. From carthamoides</em> (Willd.) DC., chlorojanerin, cynaropicrin, janerin, cebellin E repdiolide obtained.
Phytoecdysteroids are natural compounds with therapeutic benefits in both humans and animals. The effectiveness of products health potential is based on the activities potencies their active ingredients. In this study, dominant ecdysteroids—ajugasterone C, 20-hydroxyecdysone polypodine B—from Serratula coronata (S. coronata) herb were separated by column chromatography, identified spectroscopic data quantified high-performance liquid chromatography a diode array detector (HPLC-DAD). obtained...
The presence of cynaropicrin was determined in 13 species the subtribe <em>Centaureinae</em> Dumort.: <em>Centaurea declinata</em> M. B.- <em>C. leucophylla</em> B.. dealbata</em> Willd.. zangezuri</em> (Sosn.) Sosn., carthalinica</em> thracica</em> (Janka) Hayek, exarata</em> Boiss. ex Cosson, phaeopappoides</em> Bordz., <em>Chartolepis intermedia</em> Bioss., <em>Ch. glastifolia</em> (L.) Cass.,...
Hepatocellular damage by the harmful effects of xenobiotics, which increase production free radicals, is a widespread phenomenon. The extract from leaves Cynara scolymus L. available as an artichoke preparation (natural source) antioxidants may serve potential hepatoprotective factor. This study aimed to evaluate impact protective and regenerative properties on liver in three doses: 0.5; 1.0; 1.5 g/kg bw/day. evaluation was conducted measuring levels oxidative stress parameters, including...
Genus <em>Serratula</em> is known for the presence of steroid compounds which belong to group ecdysones. Former phytochemical works from late sixties and early seventies indicate, in some species, occurrence a phenolic glycoside-arbutin. This has been confirmed present work through finding an α,β-arbutin anomer <em>Serratula quinquefolia</em> M.B. New botanical data concerning classification genus suggest that species question should be regarded as belonging...
Nine new guaianolides. I of which are chlorinated, were isolated from the dried, above-ground parts <em>Centaurea bella</em> Trautv. They are: cebellin A. B, C, D, E. F, G, H and 1. l he known guaianolides centaurepensin repdiolide also found. The occurrence repin. acroptillin janerin was confirmed. Cebellin F. G. chromatographically shown to occur in adjarica</em> Alb.
Three germacranolides, as well five flavonoids, natural steroid and simple phenolic compounds, were isolated from the inflorescence of Stizolophus balsamita growing in Iran. The paper presents active compounds found for first time this species. steroids have been genus Stizolophus. MTT assay was employed to study vitro cytotoxic effects taxifolin against human fibroblasts. We also evaluate possible biological properties/cosmetic extract on skin. Sixty healthy Caucasian adult females with no...
Due to increasing resistance of pathogenic fungi antifungal treatments, new types drugs are needed. For this purpose, active substances with properties occurring in natural compounds should be considered. The herb Psephellus bellus shows strong activity and is characterized by unique guaianolides, which have an ester on C-2. Thus, a specialized method isolation testing was applied assess the pharmacological effects these guaianolides. After phytochemical analysis (chromatography spectral...
The occurrence of syringin in eight out ten investigated plant species the subtribe Centaureinae (Asteraceae) was reported. compound isolated from aerial parts plants by silica gel column chromatography methanol extracts. Contents varied 0.001 to 0.1% dried material. <em>Centaurea bella </em>Trautv. appeared be best source this (0.1% dry wt.). Syringin has been reported for first time these species.