- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Abdominal vascular conditions and treatments
- Liver Disease and Transplantation
- Gastric Cancer Management and Outcomes
- Gallbladder and Bile Duct Disorders
- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Pediatric Hepatobiliary Diseases and Treatments
- Lymphatic Disorders and Treatments
- Vascular Procedures and Complications
- Vascular Malformations Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Pancreatitis Pathology and Treatment
- Central Venous Catheters and Hemodialysis
- Advanced Radiotherapy Techniques
- Vascular anomalies and interventions
- Cancer Genomics and Diagnostics
- Cardiac tumors and thrombi
- Angiogenesis and VEGF in Cancer
- Photosynthetic Processes and Mechanisms
- Biliary and Gastrointestinal Fistulas
- Myasthenia Gravis and Thymoma
Taipei Veterans General Hospital
2015-2024
National Yang Ming Chiao Tung University
2015-2024
National Taipei University
2016-2021
National Yang Ming University Hospital
2017-2020
University of Florida
2014
Chia Nan University of Pharmacy and Science
2009
Abstract Background & Aims Transarterial chemoembolization (TACE) is a standard treatment for Barcelona Clinic Liver Cancer (BCLC) stage B hepatocellular carcinoma (HCC), but the outcome varied. This study aimed to develop model predict of TACE in HCC patients. Methods Consecutive 570 treatment‐naïve BCLC patients undergoing as initial from 2007 2016 were retrospectively enrolled. Factors associated with survival analysed. Patients 2011 constituted training cohort (n = 293), while 2012...
With the progression of molecular techniques, detection circulating plasma DNA (cpDNA) is clinically feasible. However, role cpDNA levels in gastric cancer not well understood. This study assessed mutational profile primary tumors and clarified clinical utility quantitative qualitative alterations 277 patients with advanced cancer. The concentrations were measured by TaqMan qPCR, 68 mutations 8 genes studied for mutations. median stages I, II, III 3979, 3390 4278 copies/mL, respectively,...
Lenvatinib, a multi-tyrosine kinase inhibitor that inhibits vascular endothelial growth factor and fibroblast receptors pathway, activated the immune response in tumor microenvironment. However, combination of lenvatinib anti-PD-1 has been reported early phase studies. Hence, this study aims to explore efficacy toxicity combined with nivolumab real-world setting. Advanced HCC patients who underwent (L + N group) treatment at Taipei Veterans General Hospital (Taipei, Taiwan) were reviewed...
Robotic gastrectomy has become increasingly popular in the treatment of gastric cancer, especially Asian countries. The use indocyanine green fluorescence been reported lymphatic mapping for cancer laparoscopic gastrectomy; however, there have few reports regarding robotic gastrectomy.From January 2011 to March 2016, a total 79 patients underwent cancer. Among them, intraoperative subserosal injection (n = 9) or preoperative submucosal 5) with near-infrared imaging was performed 14 patients,...
Current prediction models for early recurrence of hepatocellular carcinoma (HCC) after surgical resection remain unsatisfactory. The aim this study was to develop evolutionary learning-derived with interpretability using both clinical and radiomic features predict HCC resection.Consecutive 517 patients receiving available contrast-enhanced computed tomography (CECT) images before were retrospectively enrolled. Patients randomly assigned a training set (n = 362) test 155) in ratio 7:3. Tumor...
Summary Background The benefits of HCV eradication on distinct recurrence patterns and long‐term hepatic outcomes in patients with hepatocellular carcinoma (HCC) undergoing radiofrequency ablation (RFA) remain uncertain. This study aims to assess the impact HCC after RFA identify predictors achieving sustained virological response (SVR). Methods We retrospectively enrolled 274 receiving for HCV‐related HCC, including 73 88 treated interferon‐based (IFN) direct‐acting antivirals (DAA)...
Abstract Background Automatic segmentation of hepatocellular carcinoma (HCC) on computed tomography (CT) scans is in urgent need to assist diagnosis and radiomics analysis. The aim this study develop a deep learning based network detect HCC from dynamic CT images. Methods Dynamic images 595 patients with were used. Tumors labeled by radiologists. Patients randomly divided into training, validation test sets ratio 5:2:3, respectively. We developed hierarchical fusion strategy networks...
Selective internal radiation therapy (SIRT) is an effective treatment strategy for unresectable hepatocellular carcinoma (HCC) patients. However, the prognoses of patients with portal vein thrombosis, extra-hepatic metastases, or residual tumors remain poor when treated SIRT alone. In these patients, sequential external beam radiotherapy (EBRT) may offer a chance salvage. Here, we reported clinical outcomes and detailed dosimetry analysis 22 combination therapy.Between October 2011 May 2015,...
ABSTRACT Expression of a foreign gene to enhance plant disease resistance bacterial pathogens is favorable strategy. It has been demonstrated that expressing sweet pepper ferredoxin-I protein (PFLP) in transgenic plants can infect leaf tissue. In this study, PFLP was applied protect tomato (Lycopersicon esculentum cv. cherry Cln1558a) from the root-infecting pathogen, Ralstonia solanacearum. Independent R. solanacearum resistant T(1) lines were selected and bred produce homozygous T(2)...
Outcomes of transarterial chemoembolization (TACE) for intermediate-stage hepatocellular carcinoma (HCC) are diverse because the heterogeneity tumor burden. Radiologic pattern is one criterion determining whether TACE unsuitable. However, additional evidence required. This study determined influence radiologic morphology on outcomes initial and subsequent TACE.
Dural sinus malformation (DSM) is an extremely rare and congenital cerebrovascular that associated with dural arteriovenous fistula a large lake, which may mimic the clinical malformations of infantile shunt or vein Galen. Early diagnosis treatment DSM crucial in order to avoid irreversible brain injuries heart failure. Here, we report unusual case extensive showed good angiographic results after endovascular embolization.
Arteriovenous fistulae of the upper limbs are rare in pediatric population. They can be caused by trauma, needle puncture, or other iatrogenic injuries. A 5-year-old boy presented with progressive swelling right hand, which was initially misinterpreted as an arteriovenous malformation based on his noninvasive diagnostic work-up. He ultimately diagnosed brachiocephalic fistula catheter angiography, and then successfully treated coil embolization. This article describes relevant imaging...
Yttrium-90 radioembolization (Y90-RE) may exert an immunomodulatory effect on the tumor microenvironment of hepatocellular carcinoma (HCC). Whether host immune alterations after Y90-RE correlated with outcomes and whether affects viral hepatitis reactivation remains unclear. Between July 2014 2015, 18 patients undergoing for HCC were prospectively enrolled. Serum levels virological markers, cytokines chemokines measured at baseline, 2, 4, 12 weeks Y90-RE. Factors associated clinical...
With the advances in surgical technique and accumulation of experiences, pancreatic cancer with portal-superior mesenteric vein (PV-SMV) invasion is no longer considered as an absolute contraindication for resection. After resection PV-SMV confluence, congestion splenic (SV) may develop, resulting splenomegaly variceal formation, also known left-sided portal hypertension (LPH). Along improved postoperative prognosis, LPH induced varices are given enough time to develop eventually bleed,...
Chylothorax is characterized by lymphatic fluid accumulation in the pleural cavity caused thoracic duct and drainage disruption. Most cases of chylothorax are lymphocyte-predominant exudative effusions with high protein, low lactate dehydrogenase (LDH), elevated triglyceride levels [1]. Prompt evaluations for underlying causes key to resolve avoid recurrence. Herein, we report case a 4-year-6-month-old girl who had been receiving regular hemodialysis via left subclavian vein permcath tip...
Introduction We aimed to evaluate the effect of transcatheter arterial embolization (TAE) with iodized oil (Lipiodol) on temperature change during cryoablation (CA) for renal cell carcinoma (RCC).