Matthew J. Chan

ORCID: 0000-0002-3604-4967
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About
Contact & Profiles
Research Areas
  • Hemodynamic Monitoring and Therapy
  • Cardiac, Anesthesia and Surgical Outcomes
  • Sepsis Diagnosis and Treatment
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Heart Rate Variability and Autonomic Control
  • Trauma and Emergency Care Studies
  • Non-Invasive Vital Sign Monitoring
  • Optical Imaging and Spectroscopy Techniques
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Clinical Reasoning and Diagnostic Skills
  • Acute Kidney Injury Research
  • Aortic aneurysm repair treatments
  • Vascular Procedures and Complications
  • Cardiac tumors and thrombi
  • Central Venous Catheters and Hemodialysis
  • Respiratory Support and Mechanisms
  • Nursing Roles and Practices
  • Clinical practice guidelines implementation
  • Renal function and acid-base balance
  • Venous Thromboembolism Diagnosis and Management
  • Autopsy Techniques and Outcomes
  • Pharmaceutical Practices and Patient Outcomes
  • Cardiac Arrest and Resuscitation
  • Cardiac and Coronary Surgery Techniques
  • Blood Pressure and Hypertension Studies

Austin Hospital
2014-2019

University of Waterloo
2017

Monash University
2015-2017

Austin Health
2015

Australian Centre for Heart Health
2014

Fluid bolus therapy (FBT) is common in critically ill patients. With the exception of use patients with traumatic brain injury, FBT human albumin solution (HAS) appears safe and perhaps superior severe sepsis.To determine physiological effects 4% v 20% HAS.A retrospective observational study 202 receiving HAS a tertiary intensive care unit between April 2012 March 2013.FBT was instituted or HAS, according to clinician preference.We compared biochemical haemodynamic data groups at baseline 1,...

10.1016/s1441-2772(23)01052-9 article EN cc-by-nc-nd Critical Care and Resuscitation 2015-06-01

The primary objective was to non-invasively measure the cardiac index (CI) and associated haemodynamic parameters of healthy volunteers their changes with age. This a single centre, prospective, observational study aged between 20 59 years, using ClearSight™ (Edwards Life Sciences, Irvine, CA, USA) device. We recorded 514 observations in 97 participants. mean CI 3.5 l/min/m2 (95% confidence interval [95% CI] 3.4 3.7 l/min/m2). stroke volume (SVI) 47 ml/m2 45 49 ml/m2) systemic vascular...

10.1177/0310057x1804600306 article EN Anaesthesia and Intensive Care 2018-05-01

The renal histopathology of critically ill patients dying with acute kidney injury (AKI) in intensive care units high income countries remains uncertain.Retrospective observational assessment interobserver agreement the reporting post mortem histopathology, and ability pathologists blinded to clinical context independently identify presence pre-mortem AKI from digital images histological sections 34 teaching hospitals Australia Canada.We identified a heterogeneous cohort median age 65 years...

10.1016/s1441-2772(23)00958-4 article EN cc-by-nc-nd Critical Care and Resuscitation 2017-12-01

Avoiding hypoxaemia is considered crucial in cardiac surgery patients admitted to the intensive care unit (ICU). However, avoiding hyperoxaemia may also be important. A conservative approach oxygen therapy reduce exposure without increasing risk of hypoxaemia. Using a before-and-after design, we evaluated introduction (target SpO2 88%-92% using lowest FiO2) for surgical ICU. We studied 9041 arterial blood gas (ABG) datasets: 4298 ABGs from 245 'conventional' and 4743 298 'conservative'...

10.1177/0310057x19838753 article EN Anaesthesia and Intensive Care 2019-03-01

Medication errors involving antiepileptic drugs (AEDs) are not well studied but have the potential to cause significant harm. The authors investigated occurrence of medication incidents in Canadian hospitals that involve AEDs, their severity and contributing factors by analyzing data from two national databases.

10.12927/hcq.2017.25229 article EN Healthcare Quarterly 2017-07-31
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