Neil J. Glassford

ORCID: 0000-0003-1647-3745
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About
Contact & Profiles
Research Areas
  • Hemodynamic Monitoring and Therapy
  • Sepsis Diagnosis and Treatment
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Acute Kidney Injury Research
  • Cardiac Arrest and Resuscitation
  • Cardiac, Anesthesia and Surgical Outcomes
  • Respiratory Support and Mechanisms
  • Renal function and acid-base balance
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Intensive Care Unit Cognitive Disorders
  • Liver Disease and Transplantation
  • Diabetes Management and Research
  • Blood Pressure and Hypertension Studies
  • Thermal Regulation in Medicine
  • Chronic Kidney Disease and Diabetes
  • Airway Management and Intubation Techniques
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Venous Thromboembolism Diagnosis and Management
  • Magnesium in Health and Disease
  • Nosocomial Infections in ICU
  • Muscle and Compartmental Disorders
  • Organ Transplantation Techniques and Outcomes
  • Non-Invasive Vital Sign Monitoring
  • Poisoning and overdose treatments
  • Blood Coagulation and Thrombosis Mechanisms

Austin Hospital
2013-2024

Monash University
2014-2024

Austin Health
2011-2024

Monash Medical Centre
2024

Monash Health
2023-2024

The University of Melbourne
2013-2023

The Royal Melbourne Hospital
2018-2021

Melbourne Health
2020-2021

The University of Queensland
2019

Mater Health Services
2019

Objectives: To assess the feasibility and safety of a conservative approach to oxygen therapy in mechanically ventilated ICU patients. Design: Pilot prospective before-and-after study. Setting: A 22-bed multidisciplinary tertiary care hospital Australia. Patients: total 105 adult (18 years old or older) patients required mechanical ventilation for more than 48 hours: 51 during "conventional" before period 54 after change "conservative" therapy. Interventions: Implementation (target SpO2...

10.1097/ccm.0000000000000219 article EN Critical Care Medicine 2014-02-21

Objective: To study the effect of stress hyperlactatemia on association between hyperglycemia and mortality. Design: Retrospective cross-sectional observation study. Setting: Three ICUs using arterial blood gases with simultaneous glucose lactate measurements during ICU stay. Patients: Cohort 7,925 consecutive critically ill patients. Interventions: None. Measurements Main Results: We analyzed 152,349 lactate. performed multivariable analysis to different metrics hospital On day 1, first (p...

10.1097/ccm.0000000000000214 article EN Critical Care Medicine 2014-02-21

Frailty may help to predict intensive care unit (ICU) patient outcome. The Dalhousie Clinical Scale (DCFS) is validated assess frailty in ambulatory settings but has not been investigated Australian ICUs. We conducted a prospective three-month study of patients admitted tertiary level ICU. Within 24 hours ICU admission, the next kin or nurse charge assigned DCFS score patient. Data were obtained association between and was completed 205 348 (59%) eligible admissions. mean 3.2 (±1.6). Overall...

10.1177/0310057x1504300313 article EN Anaesthesia and Intensive Care 2015-05-01

To assess the feasibility, biochemical efficacy, and safety of liberal versus conventional glucose control in ICU patients with diabetes.Prospective, open-label, sequential period study.A 22-bed mixed a tertiary hospital Australia.We compared 350 consecutive diabetes admitted over 15 months who received preintervention population control.Liberal insulin therapy if was greater than 14 mmol/L (target: 10-14 [180-252 mg/dL]). Conventional 10 6-10 [108-180 mg/dL]).We assessed separation blood...

10.1097/ccm.0000000000003087 article EN Critical Care Medicine 2018-03-06

Objectives: To assess the feasibility, safety, and impact on relative hypoglycemia of liberal versus conventional blood glucose concentration targets in critically ill diabetic patients. Design: Prospective, open-label, sequential-period exploratory study. Setting: A 22-bed multidisciplinary ICU a tertiary care hospital Australia. Patients: Eighty adult patients, 40 from before period after period. Interventions: Blood were 6–10 mmol/L during 10–14 Measurements Main Results: We used...

10.1097/ccm.0000000000001742 article EN Critical Care Medicine 2016-04-19

SUMMARY An observational study was conducted to describe the epidemiology of bacteriuria and candiduria in intensive care unit (ICU), occurrence blood stream infection (BSI) associated with ICU-acquired positive urine culture. Between 2006 2011, 444 episodes either or defined by culture (microorganisms ⩾10 5 c.f.u./ml) occurred 406 patients. Three hundred seventy-seven (85%) were hospital-acquired including 221 which (6·4 ± 0·8 episodes/1000 ICU days). Escherichia coli most common bacteria...

10.1017/s0950268814000934 article EN Epidemiology and Infection 2014-04-24

TEG6S® and TEG5000® (Haemonetics Corp, USA) are haemostasis analysers that measure viscoelasticity properties of whole blood. Both use different mechanisms to assess similar components the coagulation process. The aim this study was agreement interchangeability between TEG6S TEG5000 analysers. 3.5 mL blood collected from 25 adult patients in a tertiary intensive care unit (ICU). Analysis performed using haemostatic platforms. Agreement platforms measured Lin's concordance coefficient (Lin's...

10.1186/s12871-019-0717-7 article EN cc-by BMC Anesthesiology 2019-03-30
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