- Health, Medicine and Society
- Psychoanalysis and Psychopathology Research
- Suicide and Self-Harm Studies
- Genetic Neurodegenerative Diseases
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Schizophrenia research and treatment
- Homicide, Infanticide, and Child Abuse
- Historical and Scientific Studies
- Functional Brain Connectivity Studies
- Treatment of Major Depression
- Neurological disorders and treatments
- Diet and metabolism studies
- Healthcare Decision-Making and Restraints
- Electroconvulsive Therapy Studies
- Mental Health Research Topics
- Sleep and related disorders
- Workplace Health and Well-being
- Psychosomatic Disorders and Their Treatments
- Neurology and Historical Studies
- Bullying, Victimization, and Aggression
- Bariatric Surgery and Outcomes
- Healthcare professionals’ stress and burnout
- Tryptophan and brain disorders
- Mental Health and Psychiatry
- COVID-19 and Mental Health
Laboratoire de Psychologie des Pays de la Loire
2012-2025
Centre Hospitalier Universitaire d'Angers
2015-2025
Université d'Angers
2013-2025
Nantes Université
2020-2025
Université Bretagne Loire
2018
University of Pittsburgh
2013
The main aim of this study was to investigate the effects Huntington's disease (HD) on cognitive and affective Theory Mind (ToM) abilities. relation ToM performance executive functions also examined. Eighteen HD patients, early in course disease, 18 healthy volunteers matched for age educational levels, were given two tasks: a nonverbal task assessing attribution intentions others revised version 'Reading Eyes' test, which is an understanding other people's mental states from their eyes....
Previous studies have shown a negative impact of the COVID-19 pandemic and its associated sanitary measures on mental health, especially among adolescents young adults. Such context may raise many concerns about long-term psychological effects. An analysis administrative databases could be an alternative complementary approach to medical interview-based epidemiological surveys monitor health population. We conducted nationwide study describe consumption anxiolytics, antidepressants hypnotics...
Summary Previous studies have highlighted the pivotal role of emotional regulation impairment in progression depressive and insomnia disorders, individually. Nevertheless, to date, no study has undertaken a direct comparison profiles individuals experiencing with or without major episode (MDE). In this study, our objective was closely examine multiple aspects among insomnia, concurrent depression. This descriptive observational involved 57 participants, comprising 27 comorbid chronic MDE, 30...
This article presents a prospective study of 71 patients infected with chronic viral hepatitis C and treated interferon alpha during one year. The objective was to assess the incidence predictive factors anxiety depression symptoms after therapy. Each patient received psychiatric assessment before, treatment, evaluations using Hamilton-anxiety MADRS scales. Results confirm great not only therapy but also treatment is discontinued. Sleep disorders ratings M4 seem be therapy's side effects....
There is evidence showing that men and women differ with regard to the processing of emotional information. However, mechanisms behind these differences are not fully understood.The sample comprised 275 (167 female) right-handed, healthy participants, recruited from community. We employed a customized affective priming task, which consisted three subtests, differing in modality prime (face, written word, sound). The targets were always words either positive or negative valence. effect was...
Huntington disease (HD) is a neurodegenerative disorder due to an excessive number of CAG repeats in the IT15 gene on chromosome 4. Studies cognitive function asymptomatic carriers have yielded contradictory results. This study compared performance 44 subjects with HD mutation (group carriers) who had no clinical signs and 39 at-risk individuals without non-carriers). Neuropsychological evaluation focused global efficiency, psychomotor speed, attentional, executive memory functions....
Imaging genetic studies showed exaggerated blood oxygenation level-dependent response in limbic structures carriers of low activity alleles serotonin transporter-linked promoter region (5-HTTLPR) as well catechol O-methyltransferase (COMT) genes. This was suggested to underlie the vulnerability mood disorders. To better understand mechanisms vulnerability, it is important investigate modulation frontal-limbic connectivity that underlies emotional regulation and control. In this study, we...
Investigating genetic modulation of emotion processing may contribute to the understanding heritable mechanisms emotional disorders. The aim present study was test effects catechol-O-methyltransferase (COMT) val158met and serotonin-transporter-linked promoter region (5-HTTLPR) polymorphisms on facial in healthy individuals.Two hundred seventy five (167 female) participants were asked complete a computerized affect recognition task, which involved four experimental conditions, each containing...
We investigated cognitive and affective Theory of Mind (ToM) empathy in patients with premanifest manifest Huntington's disease (HD). The relationship between ToM performance executive skills was also examined. Sixteen preclinical 23 clinical HD patients, 39 healthy subjects divided into 2 control groups were given a French adaptation the Yoni test (Shamay-Tsoory, S.G., Aharon-Peretz, J. (2007). Dissociable prefrontal networks for theory mind: lesion study. Neuropsychologia, 45 (3), 3054–67)...
People with Huntington's disease (HD) have been observed to lower rates of cancers.
Abstract Background Physician empathy has been associated with improved clinical outcomes and lower physician burnout. We evaluated whether forum theater (FT), a form of applied drama that allows participants to enter the performance represent actions emotions, would foster in medical students, which underlying variables be scores. Methods Three classes totaling 488 fourth-year students participated study. Forum was used explore difficult encounters patients family members: announcement...
Posttraumatic stress disorder (PTSD) is a severe and frequent affection that highly comorbid to major depressive disorder. Comorbid PTSD depression are usually treatment-resistant, with high risk of functional impairment suicide. Esketamine nasal spray recent validated treatment for treatment-resistant (TRD), but its efficacy on TRD-PTSD remains insufficiently documented. In particular, flashbacks can occur during esketamine administration their influence clinical outcomes unknown.
Adverse effects of interferon (IFN) treatment are common, and efforts to minimize these reactions considerable importance. IFN-β-1a is an established therapy for patients with relapsing–remitting multiple sclerosis (MS). Its psychiatric side debated not yet fully established. The authors report here the case a patient on MS who developed acute delirium, delusion, depression that ceased discontinuation. Although he had history recurrent major depressive disorder, his prior illness followed...