A5052662667- Diet and metabolism studies
- Obesity, Physical Activity, Diet
- Nutritional Studies and Diet
- Nutrition and Health in Aging
- Vitamin K Research Studies
- Eating Disorders and Behaviors
- Vitamin C and Antioxidants Research
- Dietary Effects on Health
- Obesity and Health Practices
- Diet, Metabolism, and Disease
- Child Nutrition and Water Access
- Food composition and properties
- Childhood Cancer Survivors' Quality of Life
- Vitamin D Research Studies
- Hormonal Regulation and Hypertension
- Bariatric Surgery and Outcomes
- Acute Lymphoblastic Leukemia research
- Mechanical Circulatory Support Devices
- Muscle metabolism and nutrition
- Physical Activity and Health
- Alcoholism and Thiamine Deficiency
- Thermoregulation and physiological responses
- Child and Adolescent Health
- Body Composition Measurement Techniques
- Cardiac Structural Anomalies and Repair
Tufts University
2015-2024
Jean Mayer Human Nutrition Research Center on Aging
2012-2023
Harvard University
2007-2015
Tufts Medical Center
2001-2015
Framingham Heart Study
2015
University of Minnesota
2015
Oregon State University
2015
Children's Nutrition Research Center at Baylor College of Medicine
2015
Agricultural Research Service
2015
Massachusetts General Hospital
2007-2013
OBJECTIVE—The aim of this study was to examine the relation between carbohydrate-related dietary factors, insulin resistance, and prevalence metabolic syndrome in Framingham Offspring Cohort. RESEARCH DESIGN AND METHODS—We examined cross-sectional associations 2,834 subjects at fifth examination (1991–1995) Study. Homeostasis model assessment resistance (HOMA-IR) calculated using following formula (fasting plasma × glucose)/22.5. The defined National Cholesterol Education Program criteria....
Caloric restriction (CR), energy intake reduced below ad libitum (AL) intake, increases life span in many species. The implications for humans can be clarified by randomized controlled trials of CR.To determine CR's feasibility, safety, and effects on predictors longevity, disease risk factors, quality nonobese aged 21-51 years, 218 persons were to a 2-year intervention designed achieve 25% CR or AL diet. Outcomes change from baseline resting metabolic rate adjusted weight ("RMR residual")...
OBJECTIVE—Vitamin K has a potentially beneficial role in insulin resistance, but evidence is limited humans. We tested the hypothesis that vitamin supplementation for 36 months will improve resistance older men and women. RESEARCH DESIGN AND METHODS—This was an ancillary study of 36-month, randomized, double-blind, controlled trial designed to assess impact with 500 μg/day phylloquinone on bone loss. Study participants were nondiabetic women (n = 355; aged 60–80 years; 60% women). The...
ABSTRACT Although caloric restriction (CR) could delay biologic aging in humans, it is unclear if this would occur at the cost of significant bone loss. We evaluated effect prolonged CR on metabolism and mineral density (BMD) healthy younger adults. Two-hundred eighteen non-obese (body mass index [BMI] 25.1 ± 1.7 kg/m2), (age 37.9 7.2 years) adults were randomly assigned to 25% (CR group, n = 143) or ad libitum (AL 75) for 2 years. Main outcomes BMD markers turnover. Other included body...
The relative influence of genetics and the environment on factors associated with cardiovascular disease (CVD) metabolic syndrome (MetS) remains unclear. We performed model-fitting analyses to quantify genetic, common environmental, unique environmental variance components CVD MetS [waist circumference, blood pressure, fasting plasma glucose insulin, homeostatic model assessment insulin resistance (HOMA-IR), lipids] in adult male female monozygotic twins reared apart or together. also...