Linru Xu

ORCID: 0000-0002-3646-4128
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About
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Research Areas
  • Forensic Fingerprint Detection Methods
  • Advanced biosensing and bioanalysis techniques
  • Electrochemical Analysis and Applications
  • Forensic and Genetic Research
  • Biosensors and Analytical Detection
  • Electrochemical sensors and biosensors
  • Ion-surface interactions and analysis
  • Quantum Dots Synthesis And Properties
  • Luminescence and Fluorescent Materials
  • Axon Guidance and Neuronal Signaling
  • bioluminescence and chemiluminescence research
  • Biometric Identification and Security
  • Microfluidic and Capillary Electrophoresis Applications
  • Identification and Quantification in Food
  • Ginseng Biological Effects and Applications
  • Nanocluster Synthesis and Applications
  • Platelet Disorders and Treatments
  • Food Quality and Safety Studies
  • Adipose Tissue and Metabolism
  • Advanced Biosensing Techniques and Applications
  • Biomarkers in Disease Mechanisms
  • Bacillus and Francisella bacterial research
  • Digital Media Forensic Detection
  • Wood and Agarwood Research
  • Erythrocyte Function and Pathophysiology

Soochow University
2017-2023

China Pharmaceutical University
2015-2023

Zhejiang University
2012-2019

Cleveland Clinic
2017

Leiden University Medical Center
2017

The Wallace H. Coulter Department of Biomedical Engineering
2017

Georgia Institute of Technology
2017

Hangzhou Xixi hospital
2014

Northeastern University
2010-2012

By exposing an electrode surface with a latent fingerprint to electrochemiluminescence (ECL)-generating luminophore, ECL is produced from the not covered by fingerprint, generating negative image (see picture, left). The can also be pre-stained luminophores, which generates and yields positive (right). ITO=indium tin oxide. Detailed facts of importance specialist readers are published as ”Supporting Information”. Such documents peer-reviewed, but copy-edited or typeset. They made available...

10.1002/anie.201203815 article EN Angewandte Chemie International Edition 2012-07-02

The aggregation-induced emission of tetraphenylethene was explored for enhancing the visualization latent fingerprints on wet non-porous surfaces.

10.1039/c2cc30553d article EN Chemical Communications 2012-01-01

Abstract A simple method termed immunological multimetal deposition (iMMD) was developed for rapid visualization of sweat fingerprints with bare eyes, by combining the conventional MMD immunoassay technique. In this approach, antibody‐conjugated gold nanoparticles (AuNPs) were used to specifically interact corresponding antigens in fingerprint residue. The AuNPs serve as nucleation sites autometallographic silver particles from staining solution, generating a dark ridge pattern visual...

10.1002/anie.201404416 article EN Angewandte Chemie International Edition 2014-07-30

Abstract The electrochemiluminescence (ECL) of porous silicon (pSi) has attracted great interest for its potential application in display technology and chemical sensors. In this study, we found that pSi with a different surface chemistry displayed an apparently dynamic ECL process. An image‐contrast was established on the basis intrinsic mechanism As proof principle, visualization latent fingerprints (LFPs) situ detection TNT demonstrated by using ECL‐based technology.

10.1002/anie.201404948 article EN Angewandte Chemie International Edition 2014-07-17

The combined use of electrochemiluminescence imaging and enzyme immunoassay allows both identification latent fingermarks recognition protein/polypeptide secretions.

10.1039/c4cc03466j article EN Chemical Communications 2014-01-01

Aggregation-induced emission was explored for the visual enhancement of latent fingerprints deposited on wet non-porous surfaces.

10.1039/c3an02367b article EN The Analyst 2014-01-01

Accumulating evidence suggests a role of semaphorins in vascular homeostasis. Here, we investigate the Sema7A (semaphorin 7A) atherosclerosis and its underlying mechanism.Using genetically engineered Sema7A-/-ApoE-/- mice, showed that deletion attenuates atherosclerotic plaque formation primarily aorta ApoE-/- mice on high-fat diet. A higher level atheroprone lesser curvature correlation with disturbed flow. This notion is supported by elevated expression human umbilical venous endothelial...

10.1161/atvbaha.117.310491 article EN Arteriosclerosis Thrombosis and Vascular Biology 2017-12-21

Behandelt man eine Elektrodenoberfläche, auf der sich ein latenter Fingerabdruck befindet, mit einem Elektrochemilumineszenz (ECL) erzeugenden Luminophor, so geben die Oberflächenbereiche, nicht vom bedeckt sind, ECL ab, und erhält Negativbild (links; ITO=Indiumzinnoxid). Wird aber Luminophor vorbehandelt, ECL-Positivbild (rechts).

10.1002/ange.201203815 article DE Angewandte Chemie 2012-07-02

An ECL imaging biosensor was fabricated for detecting glucose, lactate and choline, as well simultaneous multicomponent assay.

10.1039/c4an00687a article EN The Analyst 2014-01-01

Surface-assisted laser desorption/ionization (SALDI) mass spectrometry (MS) has become an attractive complementary approach to matrix-assisted (MALDI) MS. SALDI MS great potential for the detection of small molecules because absence applied matrix. In this work, a functionalized porous TiO2 film immobilized with gold nanoparticles (AuNPs-FPTDF) was prepared enhance performance. The films were by facile sol–gel method and chemically dense loading AuNPs. AuNPs-FPTDF showed superior performance...

10.1021/acsami.0c12949 article EN ACS Applied Materials & Interfaces 2020-08-27

Visualization and detection of latent fingerprints (LFPs) on metal surfaces are highly practical importance, e.g., in identifying gun cartridges. We report herein the visualization LFPs stainless steel by electrochemiluminescence (ECL). Since organic residues, such as fatty acids, fingerprint deposit make underlying surface electrochemically inert or less active, an ECL reaction occurs only portions untouched fingertip, hence generating a negative image fingerprint. The popular solution,...

10.1039/c3an00110e article EN The Analyst 2013-01-01

Herein we report the combination of enzyme-linked immunoassay and pattern recognition analysis for extracting both chemical spatial information from latent fingermarks (LFMs). The development approach basically involves two steps, namely, specific protein polypeptide secretions present in ridge residues LFMs by horseradish peroxidase (HRP)-labeled antibodies HRP-catalyzed chemiluminescent (CL) reaction between luminol H2O2. emitted light can spatially resolve ridges, generating a bright...

10.1021/acs.analchem.9b02631 article EN Analytical Chemistry 2019-09-16

Functionalized CdTe-CdS core-shell quantum dots (QDs) were synthesized in aqueous solution via water-bathing combined hydrothermal method using L-cysteine (L-Cys) as a stabilizer. This possesses both the advantages of and methods for preparing high-quality QDs with markedly reduced synthesis time, better stability than lone method. The characterized by transmission electronic microscopy powder X-ray diffraction photoelectron spectroscopy. structure showed enhanced fluorescence photo nude...

10.1002/bio.1188 article EN Luminescence 2010-07-06

Abstract The electrochemiluminescence (ECL) of porous silicon (pSi) has attracted great interest for its potential application in display technology and chemical sensors. In this study, we found that pSi with a different surface chemistry displayed an apparently dynamic ECL process. An image‐contrast was established on the basis intrinsic mechanism As proof principle, visualization latent fingerprints (LFPs) situ detection TNT demonstrated by using ECL‐based technology.

10.1002/ange.201404948 article EN Angewandte Chemie 2014-07-17

Obesity and related diseases are becoming a growing risk for public health around the world due to westernized lifestyle. Sema7A, an axonal guidance molecule, has been known play role in neurite growth, bone formation, immune regulation. Whether Sema7A participates obesity metabolic is unknown. As several SNPs SEMA7A its receptors were found correlate with BMI parameters human population, we investigated potential of hepatic steatosis.GWAS GEPIA database was used analyze correlation...

10.1016/j.molmet.2023.101698 article EN cc-by-nc-nd Molecular Metabolism 2023-02-25
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