Guilherme Jorge Costa

ORCID: 0000-0002-3699-0590
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About
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Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Global Cancer Incidence and Screening
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Research Studies
  • COVID-19 Clinical Research Studies
  • COVID-19 and healthcare impacts
  • Galectins and Cancer Biology
  • Glycosylation and Glycoproteins Research
  • Long-Term Effects of COVID-19
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Women's cancer prevention and management
  • COVID-19 and Mental Health
  • Cervical Cancer and HPV Research
  • SARS-CoV-2 and COVID-19 Research
  • Healthcare Regulation
  • Occupational Health and Burnout
  • Nutrition, Genetics, and Disease
  • Frailty in Older Adults
  • Child and Adolescent Health
  • Economic and Financial Impacts of Cancer
  • Gastric Cancer Management and Outcomes
  • Chronic Disease Management Strategies
  • Management of metastatic bone disease
  • Health, Medicine and Society
  • Advances in Oncology and Radiotherapy

Instituto de Medicina Integral Professor Fernando Figueira
2016-2025

Universidade Federal de São Paulo
2006-2024

Hospital de Câncer de Pernambuco
2018-2024

Centro Hospitalar do Baixo Vouga
2021-2022

Instituto de Tecnologia de Pernambuco
2016

Kawasaki Hospital
2001

ABSTRACT Objective: To characterize the clinical and histological profile, as well treatment patterns, of patients with early-stage, locally advanced (LA), or advanced/metastatic (AM) lung cancer, diagnosed between 2000 2014, in Brazil. Methods: This was an analytical cross-sectional epidemiological study employing data obtained for 2000-2014 period from hospital cancer registries two institutions Brazil: José Alencar Gomes da Silva National Cancer Institute, city Rio de Janeiro; São Paulo...

10.1590/1806-3713/e20180251 article EN cc-by-nc Jornal Brasileiro de Pneumologia 2020-01-01

Coronavirus disease 2019 (COVID-19) and cancer are serious public health problems worldwide. However, little is known about the risk factors of in-hospital mortality among COVID-19 patients with without in Brazil. The objective this study was to evaluate compare according gender topography during year 2020 Brazil.This a secondary data hospitalized adult diagnosis by real-time polymerase chain reaction testing were collected from Influenza Epidemiological Surveillance Information System.This...

10.1002/cncr.33832 article EN Cancer 2021-08-03

To determine the clinical profile of COVID-19 inpatients who were vaccinated prior to hospitalization and compare risk factors for death 28-day survival rate between those with one, two, or three doses unvaccinated inpatients.This was a retrospective observational cohort study involving patients admitted referral hospital in city Recife, Brazil, July 2020 June 2022.The sample comprised 1,921 inpatients, 996 whom (50.8%) hospitalization. After adjusting mortality patients, undergoing invasive...

10.36416/1806-3756/e20230145 article EN cc-by-nc Jornal Brasileiro de Pneumologia 2023-08-11

Abstract Background The immune system is recognized to have therapeutic potential destroy cancer cells. Soluble T‐cell immunoglobulin mucin domain‐3 (sTIM‐3) and its ligand galectin 9 (Gal‐9) cause suppression of cytokine production, cell cycle arrest death. sTIM‐3 Gal‐9 levels may prognostic implications in non‐small‐cell lung (NSCLC) patients. Methods This prospective cohort study was performed at Instituto de Medicina Integral Prof. Fernando Figueira, Recife, Pernambuco, Brazil....

10.1002/jso.27758 article EN Journal of Surgical Oncology 2024-07-24

Aim: The aim of this study was to evaluate the frequency and median time for development metastases prognosis by metastatic site after diagnosis non-small-cell lung cancer (NSCLC). Patients & methods: This cohort conducted with 1096 patients diagnosed NSCLC between 2006 2014. Results: most prevalent respiratory system. nervous adrenal systems presented longest metastases. 6-month survival varied from 68.2% liver 79.9% Bone were associated a higher risk death. Conclusion: system OS death...

10.2217/fon-2020-0587 article EN Future Oncology 2021-01-29
K. P. Dawson Philippe Frossard Alice Ravenscroft J. F. Schoeman Peter R. Donald and 95 more Z. Hijazi M.Z. Haider Jurriaan M. Peters H Vince Immunogenicity Friesen Somsak Lolekha A Hiranchote S Simaathien Nafissa Osman Kenneth Challis M. Cotiro Gunnar Nordahl Staffan Bergström V. Kalra J.K Grover Ahuja Gk Suresh Kumar Rathi Shraddha Gulati Naveen Kalra Chinnathambi N. Kamalaratnam Gagandeep Kang Chellam Kirubakaran D. Prasanna Rajan D. Daniel M. Mathan V. I. Mathan Yakov Sivan Y. Alwin Jayakumar C. Arumughan A. Sundaresan C. Balachandran J C Job Sathyaseelan S. Deepa S Shihina Malathi Damodaran C.S. Soman V. Raman Kutty Phulen Sarma Echocardiographic Characteristics Rosana Cipolotti Guilherme Jorge Costa William Gustavo Lima Raquel Porto Alegre Valente Franco Eneri Vieira de Souza L. Mello A Dal Fabbro Rafael Gurgel Luís E. Cuevas Om P. Mishra Tripti Dhawan P. N. Singla Vishva M. Dixit Neil Arya Gunjan Nath Serap Turan Serap Saygı Zübeyir Kılıç Osman Acar Ri De Freitas Aragão Muteen Fatima Pedro Ferreira de Albuquerque M Gonçalves De Mello Ricardo Arraes de Alencar Ximenes Dorothy J. VanderJagt Maria Regina Morales Tom D. Thacher Maureen H. Diaz Robert H. Glew K.A.W. Karunasekera Jayan D. Jayasinghe L Alwis Ashraf Soliman Ashraf Madkour M Galil Mahmound El Zalabany Shahid Aziz Behnaz Ansari P Manji Georgina Msemo B Tamim Erica Thomas Ana Ceballos Diana Liberatore Mirna Biglione M De Los Angeles Pando L. M. Peralta María Mercedes Ávila P McMaster Nnenna Ezeilo H Freisen Naomi Pomat John Vince D Kurtzhals J Ofore-Adjei

10.1093/tropej/47.6.l article EN Journal of Tropical Pediatrics 2001-12-01

Abstract Background Cancer immunotherapy has had an important role in oncologic therapeutics for patients with non‐small cell lung cancer (NSCLC) using checkpoint inhibitors. We will explore the possible prognosis biomarker candidates such as: soluble OX40 (sOX40), OX40L (sOX40L), Glucocorticoid‐induced tumor necrosis factor receptor family‐related (GITR), and their ligand (GITRL), 4‐1BB or superfamily 9 (TNFRS9) inducible T co‐stimulator (ICOS) peripheral blood of NSCLC patients. Methods...

10.1002/jso.27763 article EN Journal of Surgical Oncology 2024-07-07

Summary In the backdrop of global obesity pandemic, recognized as a notable risk factor for coronavirus disease 2019 (COVID‐19) complications, study aims to explore clinical and epidemiological attributes hospitalized COVID‐19 patients throughout 2021 in Brazil. Focused on four distinct age cohorts, investigation scrutinizes parameters such intensive care unit (ICU) admission frequency, invasive mechanical ventilation (IMV) usage, in‐hospital mortality among individuals with without obesity....

10.1111/cob.12698 article EN Clinical Obesity 2024-08-09

Resumo Objectives: to determine the clinical and epidemiological profile of long post-COVID syndrome (LPCS) quality life among female survivors compared males after hospitalization for COVID-19 in city Recife, Brazil. Methods: a prospective cohort study analyzed demographic data during hospitalization, as well LPCS questionnairewhereasdata was collected by telecare at three, sixand 12 months hospital discharge. Logistic regression used explore association between variables each dimension...

10.1590/1806-9304202400000267 article EN cc-by Revista Brasileira de Saúde Materno Infantil 2024-01-01

Abstract Objectives: to determine the clinical and epidemiological profile of long post-COVID syndrome (LPCS) quality life among female survivors compared males after hospitalization for COVID-19 in city Recife, Brazil. Methods: a prospective cohort study analyzed demographic data during hospitalization, as well LPCS questionnairewhereasdata was collected by telecare at three, sixand 12 months hospital discharge. Logistic regression used explore association between variables each dimension...

10.1590/1806-9304202400000267-en article EN cc-by Revista Brasileira de Saúde Materno Infantil 2024-01-01

O microbioma intestinal, composto por trilhões de microrganismos, desempenha um papel crucial na manutenção da saúde humana. Estudos recentes têm demonstrado uma conexão significativa entre o e a metabólica, influenciando condições como obesidade, diabetes tipo 2 síndrome metabólica. Esta revisão aborda relação intestinal destacando os mecanismos envolvidos as implicações para novas abordagens terapêuticas.

10.34119/bjhrv7n10-207 article PT Brazilian Journal of Health Review 2024-12-16
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