A5045998120- Forensic and Genetic Research
- Genetic diversity and population structure
- Forensic Anthropology and Bioarchaeology Studies
- Archaeology and ancient environmental studies
- Pleistocene-Era Hominins and Archaeology
- Genetic and phenotypic traits in livestock
- Wildlife Ecology and Conservation
- Environmental DNA in Biodiversity Studies
- Genomics and Phylogenetic Studies
- Yersinia bacterium, plague, ectoparasites research
- Evolution and Paleontology Studies
- Identification and Quantification in Food
- Genetic Mapping and Diversity in Plants and Animals
- Meat and Animal Product Quality
- Aquaculture disease management and microbiota
- Language and cultural evolution
- Paleontology and Stratigraphy of Fossils
- melanin and skin pigmentation
- Geological and Geophysical Studies
- Bone and Dental Protein Studies
- Paleopathology and ancient diseases
- Isotope Analysis in Ecology
- Fractal and DNA sequence analysis
- Ion Channels and Receptors
- Bat Biology and Ecology Studies
University of Ferrara
2016-2023
Universidade da Coruña
2016-2023
University of Potsdam
2014-2020
University of York
2013-2017
Universidade de Santiago de Compostela
2004-2007
University of Parma
2006-2007
National Directorate of Geology
1989
Abstract The Great Hungarian Plain was a crossroads of cultural transformations that have shaped European prehistory. Here we analyse 5,000-year transect human genomes, sampled from petrous bones giving consistently excellent endogenous DNA yields, 13 Neolithic, Copper, Bronze and Iron Age burials including two to high (~22 × ) seven ~1 coverage, investigate the impact these on Europe’s genetic landscape. These data suggest genomic shifts with advent Ages, interleaved periods genome...
Abstract We extend the scope of European palaeogenomics by sequencing genomes Late Upper Palaeolithic (13,300 years old, 1.4-fold coverage) and Mesolithic (9,700 15.4-fold) males from western Georgia in Caucasus a (13,700 9.5-fold) male Switzerland. While we detect Palaeolithic–Mesolithic genomic continuity both regions, find that hunter-gatherers (CHG) belong to distinct ancient clade split ∼45 kya, shortly after expansion anatomically modern humans into Europe ancestors Neolithic farmers...
Abstract In 2012, a skeleton was excavated at the presumed site of Grey Friars friary in Leicester, last-known resting place King Richard III. Archaeological, osteological and radiocarbon dating data were consistent with these being his remains. Here we report DNA analyses both skeletal remains living relatives We find perfect mitochondrial match between sequence obtained from one relative, single-base substitution when compared second relative. Y-chromosome haplotypes male-line do not...
Leopard complex spotting is a group of white patterns in horses caused by an incompletely dominant gene (LP) where homozygotes (LP/LP) are also affected with congenital stationary night blindness. Previous studies implicated Transient Receptor Potential Cation Channel, Subfamily M, Member 1 (TRPM1) as the best candidate for both CSNB and LP. RNA-Seq data pinpointed 1378 bp insertion intron TRPM1 potential cause. This insertion, long terminal repeat (LTR) endogenous retrovirus, was completely...
The transition from hunting and gathering to farming involved profound cultural technological changes. In Western Central Europe, these changes occurred rapidly synchronously after the arrival of early farmers Anatolian origin [1-3], who largely replaced local Mesolithic hunter-gatherers [1, 4-6]. Further east, in Baltic region, was gradual, with little or no genetic input incoming [7]. Here we use ancient DNA investigate relationship between Lower Danube basin, a geographically intermediate...
Abstract Ancient DNA studies have revolutionized the study of extinct species and populations, providing insights on phylogeny, phylogeography, admixture demographic history. However, inferences behaviour sociality been far less frequent. Here, we investigate complete mitochondrial genomes Late Pleistocene cave bears middle Holocene brown that each inhabited multiple geographically proximate caves in northern Spain. In bears, find that, although most were occupied simultaneously, almost...
Being at the western fringe of Europe, Iberia had a peculiar prehistory and complex pattern Neolithization. A few studies, all based on modern populations, reported presence DNA likely African origin in this region, generally concluding it was result recent gene flow, probably during Islamic period. Here, we provide evidence much older flow from Africa to by sequencing whole genomes four human remains northern Portugal southern Spain dated around 4000 years BP (from Middle Neolithic Bronze...
Abstract A consensus microsatellite-based linkage map of the turbot (Scophthalmus maximus) was constructed from two unrelated families. The mapping panel derived a gynogenetic family 96 haploid embryos and biparental diploid 85 full-sib progeny with known phase. total 242 microsatellites were mapped in 26 groups, six markers remaining unlinked. length 1343.2 cM, an average distance between 6.5 ± 0.5 cM. Similar female male maps evidenced. However, mean recombination at common intervals...
Abstract Farming was first introduced to southeastern Europe in the mid-7 th millennium BCE – brought by migrants from Anatolia who settled region before spreading throughout Europe. To clarify dynamics of interaction between farmers and indigenous hunter-gatherers where they met, we analyze genome-wide ancient DNA data 223 individuals lived surrounding regions 12,000 500 BCE. We document previously uncharacterized genetic structure, showing a West-East cline ancestry hunter-gatherers, show...
Leopard complex spotting is inherited by the incompletely dominant locus, LP, which also causes congenital stationary night blindness in homozygous horses. We investigated an associated single nucleotide polymorphism TRPM1 gene 96 archaeological bones from 31 localities Late Pleistocene (approx. 17 000 YBP) to medieval times. The first genetic evidence of LP Europe dates back Pleistocene. tested for temporal changes allele frequency and estimated coefficients selection means approximate...
Abstract Little is known about the genetic prehistory of Sardinia because scarcity pre-Neolithic human remains. From a perspective, modern Sardinians are as outliers in Europe, showing unusually high levels internal diversity and close relationship to early European Neolithic farmers. However, how far this peculiar structure extends it originated was date impossible test. Here we present first oldest complete mitochondrial sequences from Sardinia, dated back 10,000 yBP. These two...
ABSTRACT Ancient DNA studies have revolutionised the study of extinct species and populations, providing insights on phylogeny, phylogeography, admixture demographic history. However, inferences behaviour sociality been far less frequent. Here, we investigate complete mitochondrial genomes Late Pleistocene cave bears middle Holocene brown that each inhabited multiple geographically proximate caves in northern Spain. In bears, find that, although most were occupied simultaneously, almost...
When studying an extinct species such as the cave bear (Ursus spelaeus ROSENMÜLLER 1794), it is possible to apply a variety of molecular biology techniques study stable isotopes or mitochondrial DNA (mDNA) infer patterns behaviour physiology that would otherwise remain concealed. Throughout Europe and along time, differences in isotopic values (δ13C δ15N) bears arise from environmental Pleistocene climatic evolution. The climate determines hibernation length, during which undergo particular...
ABSTRACT The ability to access genomic information from ancient samples has provided many important biological insights. Generating such palaeogenomic data requires specialised methodologies, and a variety of procedures for all stages sample preparation have been proposed. However, the specific effects biases introduced by alternative laboratory is insufficiently understood. Here, we investigate three DNA isolation two library protocols on obtained four Pleistocene subfossil bones. We find...
Modern exploration for hydrocarbons began in Mozambique 1981. The newly‐acquired data augment those gathered the territory prior to plitical independence 1975, and provide a basis an updated appraisal of country's hydrocarbon potential. This is concentrated marginal Rovuma Basins, whose development was initiated during break‐up Gondwana. “fit” Madagascar against coastal Tanzania Somailia accepted as representing region's early plate‐tectonic configuration. Both basins display polyphase...
We report genome-wide ancient DNA from 44 Near Easterners ranging in time between ~12,000-1,400 BCE, Natufian hunter-gatherers to Bronze Age farmers. show that the earliest populations of East derived around half their ancestry a ‘Basal Eurasian’ lineage had little if any Neanderthal admixture and separated other non-African lineages prior separation each other. The first farmers southern Levant (Israel Jordan) Zagros Mountains (Iran) were strongly genetically differentiated, descended local...