A5067701915- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- Mycobacterium research and diagnosis
- Antifungal resistance and susceptibility
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and healthcare impacts
- Fungal Infections and Studies
- Diagnosis and treatment of tuberculosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Mosquito-borne diseases and control
- Pneumonia and Respiratory Infections
- Intensive Care Unit Cognitive Disorders
- Bacterial Infections and Vaccines
- Hematological disorders and diagnostics
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Skin and Cellular Biology Research
- Nosocomial Infections in ICU
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Psychosomatic Disorders and Their Treatments
- Malaria Research and Control
- COVID-19 diagnosis using AI
- Respiratory Support and Mechanisms
- Viral Infections and Vectors
All India Institute of Medical Sciences
2015-2025
Sharda University
2024
New Delhi Tuberculosis Center
2024
Science Health Allied Research Education
2024
All India Institute of Medical Sciences Bhopal
2020-2022
All India Institute of Medical Sciences Raipur
2020-2022
Marymount University
2017
Post COVID-19 sequelae are a constellation of symptoms often reported after recovering from COVID-19. There is need to better understand the clinical spectrum and long-term course this entity. The aim study describe features risk factors post in North Indian population. This prospective observational was conducted at tertiary healthcare centre Northern India between October 2020 February 2021. Patients aged >18 years with laboratory-confirmed were recruited least two weeks diagnosis, details...
There is a paucity of data on the clinical presentations and outcomes Corona Virus Disease-19 (COVID-19) in patients with underlying liver disease. We aimed to summarize COVID-19-positive compare historical controls.Patients known chronic disease who presented superimposed COVID-19 (n = 28) between 22 April 2020 June were studied. Seventy-eight cirrhotic without included as controls for comparison.A total 28 (two cirrhosis, one compensated sixteen acute decompensation [AD], nine...
BBV152 is a whole-virion inactivated SARS-CoV-2 vaccine that has been deployed in India. The results of the phase 3 trial have shown clinical efficacy BBV152. We aimed to evaluate effectiveness against symptomatic RT-PCR-confirmed infection.We conducted test-negative, case-control study among employees All India Institute Medical Sciences (a tertiary care hospital New Delhi, India), who had symptoms suggestive COVID-19 and an RT-PCR test for during peak second wave pandemic between April 15...
Abstract Background People living with HIV (PLWH) face the dual challenge of human immunodeficiency virus(HIV) infection and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. It is associated outcomes a higher risk mortality. In January 2021, vaccination campaign against SARS-CoV-2 was launched in India started mass administration two types vaccines. The vaccines used on large scale were, recombinant, replication-deficient chimpanzee adenovirus vectored vaccine/ ChAdOx1...
The pandemic caused by SARS-CoV-2 (SCoV-2) has impacted the world in many ways and virus continues to evolve produce novel variants with ability cause frequent global outbreaks. Although advent of vaccines abated burden, they were not effective against all SCoV-2. This trend warrants shifting focus on development small molecules targeting crucial proteins viral replication machinery as therapeutic solutions. PLpro is a enzyme having multiple roles during life cycle well-established drug...
Though invasive pulmonary aspergillosis is a well known complication of COVID-19 pneumonia, indolent forms have been rarely described.We prospectively collected the clinico-radio-microbiological data 10 patients subacute (SAIA), who presented to our hospital with recent history pneumonia along cavitary lung disease, positive IgG (against Aspergillus) or without respiratory samples for Aspergillus spp.The mean age presentation SAIA was 50.7 ± 11.8 years. All had recently recovered from severe...
Abstract Background Chronic pulmonary aspergillosis (CPA) is known to complicate patients with post‐tubercular lung disease. However, some evidence suggests that CPA might co‐exist in newly‐diagnosed tuberculosis (P.TB) at diagnosis and also develop during therapy. The objective of this study was confirm the presence newly diagnosed P.TB baseline end‐of‐TB‐therapy. Materials Methods This prospective longitudinal included patients, followed up third month end‐of‐TB‐therapy symptom assessment,...
Stenotrophomonas maltophilia is an emerging gram-negative pathogen that was previously labeled as a colonizer. Nowadays, with multiple antibiotic usage along certain host factors, infections caused by this organism are getting attention. We hereby report two cases of ventilator-associated pneumonia in postoperative infants cardiac intensive care unit (ICU). How to cite article: Baidya A, Kodan P, Fazal F, Tsering S, Menon RP, Jorwal et al. maltophilia: More than Just Colonizer! Indian J Crit...
Background The emergence of drug-resistant tuberculosis (TB), is a major menace to cast off TB worldwide. Line probe assay (LPA; GenoType MTBDRplus ver. 2) and Xpert MTB/RIF assays are two rapid molecular detection/diagnostic tests. To compare the performance LPA for early diagnosis rifampicin-resistant (RR) in acid-fast bacillus (AFB) smear-positive negative sputum samples. Methods A total 576 presumptive AFB patients were selected subjected microscopy, recent version (GenoType tests...
Background: Resource-limited settings like India need a simple, quick, and temperature-independent point-of-care diagnostic test that can diagnose tuberculous meningitis (TBM) at the earliest. Methods: A prospective study was carried out tertiary care center in North wherein 50 subjects suspected of TBM were recruited followed up for six months between January 2019 December 2020. The aim to evaluate performance loop-mediated isothermal amplification (TB-LAMP) diagnosing as compared composite...
Mucormycosis is an uncommon aggressive fungal infection usually seen in immunocompromised hosts or patients with burns and trauma. The common presentations include rhino-orbital-cerebral pulmonary involvement. Osteoarticular involvement a rare presentation of this disease. We present two cases osteoarticular mucormycosis pelvis long bones the lower limb, one patient burn injury other chronic granulomatous disease, hitherto rarely reported association. Delayed diagnosis setting where...
Abstract Introduction: The quality-of-life in individuals with diabetes is also dependent upon the quality of family relationships and general well-being caregivers because patient depends on them to uphold community. Only limited studies have assessed psychological health diabetes. Aims Objective: current study aims at comparison depression anxiety levels among patients their caregivers. Materials Methods: Fifty consecutive patients-care giver dyads subjects having type 2 were recruited an...
A 15 year old girl presented with complaints of prolonged fever and recurrent episodes hemoptysis. Initial investigation showed pancytopenia radiological imaging was suggestive necrotizing pneumonia. Subsequently, mucor isolated from bronchoalveolar lavage fluid, but even on appropriate medications her condition kept deteriorating. She had multiple bouts hemoptysis a repeat chest dissemination mucormycosis to pulmonary vein heart. Bone marrow biopsy identified acute lymphoblastic leukemia...
Background Mutations in atpE gene or transcriptional repressor Rv0678 associated with inhibition of adenosine 5'-triphosphate synthase and upregulation efflux pumps, respectively, may potentially lead to vitro resistance bedaquiline. This is the first study from India, which looks at mutations this novel drug. Methods In 2019 (January June), a total 68 laboratory-confirmed pre-extensively drug-resistant tuberculosis (XDR-TB) (fluoroquinolone resistant [n = 52] second-line injectables 12]) 4...
The clinical profile and risk factors for mortality in dengue fever have evolved over the years. all-cause admitted patients is around 6%. We aimed to evaluate recent change trends of characteristics in-hospital adults with fever. This a retrospective study on confirmed medical unit tertiary care center North India. Medical records between January 2011, December 2016 were reviewed. Chi-squared tests Bonferroni correction multiple testing used identify mortality. 232 included, which 66.8%...
Background: Acanthosis nigricans (AN) is a skin condition associated with insulin resistance, and highly correlated hyperinsulinemia, type 2 diabetes, obesity; scarcity of information regarding its status in young adult subjects. Aim: To determine the association between presence AN biochemical parameters anthropometric variables. Subjects Methods: This analytical cross-sectional study included male subjects from outpatient department Medicine tertiary care center North India. They were...
Use of systemic corticosteroids is well-established in COVID-19 patients with hypoxia; however, there scant data on its role mild disease and prolonged symptoms as a measure to prevent progression. The aim this study evaluate the preventing hypoxia (SpO2 ≤ 93% room-air) among patients. An observational was conducted symptomatic taking oral attending institute teleconsultation facility between 10th-30th June 2021. Patients who were already for other indication or required oxygen...
Invasive fungal infections (IFI) are commonly seen in immunosuppressed individuals but their epidemiology critically ill patients has not been well described. The aim of this study was to determine the frequency, risk factors and outcome invasive a medical intensive care unit. A prospective observational carried out between August 2016 March 2018 Patients above age 14 years with endotracheal intubation and/or central venous catheter for at-least three days sepsis (not responding 48 hours...