A5089083362- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Nail Diseases and Treatments
- Sinusitis and nasal conditions
- Plant Pathogens and Fungal Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Yeasts and Rust Fungi Studies
- Infectious Diseases and Mycology
- Oral microbiology and periodontitis research
- Infectious Diseases and Tuberculosis
- Physical Education and Training Studies
- Plasma Applications and Diagnostics
- Parasitic Diseases Research and Treatment
- Dental Research and COVID-19
- SARS-CoV-2 and COVID-19 Research
- Pneumonia and Respiratory Infections
- Fungal and yeast genetics research
- Genomics and Rare Diseases
- Inhalation and Respiratory Drug Delivery
- Urological Disorders and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Vascular Malformations Diagnosis and Treatment
- Antibiotic Use and Resistance
- Gender Diversity and Inequality
- Physical Activity and Health
All India Institute of Medical Sciences
2022-2025
All India Institute of Medical Sciences Bhopal
2023-2024
Icahn School of Medicine at Mount Sinai
2024
All India Institute of Medical Sciences Raipur
2023-2024
Dayanand Medical College & Hospital
2022-2023
Post Graduate Institute of Medical Education and Research
2012-2022
The rise in multidrug-resistant pathogens and biofilms has become a significant issue to address. In the of hour, various innovating technologies are being used combat these deadly pathogens. One emerging is cold atmospheric plasma (CAP) which could bring revolution this aspect. antimicrobial property CAP makes it powerful tool inactivation biofilms. This review paper emphasizes how efficacy affected by types devices, operating gas composition flow rate, variation source frequency, voltage...
The rise in multidrug-resistant (MDR) ESKAPE bacteria have become a major therapeutic challenge globally. Recently, novel cold atmospheric pressure plasma (CAP) as an antimicrobial is becoming popular. In this study, indigenously developed AC CAP jet (CAPJ) fed with argon gas was used to evaluate its efficacy on these isolated from clinical specimens, such urine, blood, and sputum tertiary care hospital India. difference CAP's activity Gram-negative bacilli (MDR E. coli) Gram-positive cocci...
Abstract Background Candida auris, a multidrug-resistant nosocomial pathogen, has emerged globally as major threat to healthcare settings, and several hospital outbreaks continue be reported. We attempted study the risk factors associated with C. auris colonization its antifungal susceptibility at tertiary center. 1.Distribution of isolates Methods A prospective observational was conducted over 18 months. Patients were screened for by axillary, groin swabs, urine cultures within 48 hours...
Abstract Background Post-mortem studies have shown significant underestimation of invasive pulmonary aspergillosis in critically ill ICU patients, resource-limited settings due to limited awareness, diagnostic capabilities, and ubiquitous presence Aspergillus spores. The revised BM AspICU algorithm for patients was validated a historical cohort, with changes the host imaging criteria as well inclusion PCR assays. This study first time prospectively evaluated utility cohort using post-mortem...
IntroductionInvasive mould infections (IMIs) are a leading cause of death in patients with compromised immune systems. Proven invasive infection requires detection fungus by histopathological analysis biopsied specimen, sterile culture, or fungal DNA amplification PCR tissue. However, the clinical performance assay on blood samples taken from suspected disease has not been fully evaluated, particularly for differential diagnosis aspergillosis (IA) and Mucormycosis (IM).ObjectivesTo assess...
Genomic analyses are widely applied to epidemiological, population genetic and experimental studies of pathogenic fungi. A wide range methods employed carry out these analyses, typically without including controls that gauge the accuracy variant prediction. The importance tracking outbreaks at a global scale has raised urgency establishing high-accuracy pipelines generate consistent results between research groups. To evaluate currently for whole-genome detection elaborate best practices...
Abstract Background Chronic pulmonary aspergillosis (CPA) is known to complicate patients with post‐tubercular lung disease. However, some evidence suggests that CPA might co‐exist in newly‐diagnosed tuberculosis (P.TB) at diagnosis and also develop during therapy. The objective of this study was confirm the presence newly diagnosed P.TB baseline end‐of‐TB‐therapy. Materials Methods This prospective longitudinal included patients, followed up third month end‐of‐TB‐therapy symptom assessment,...
Abstract Background Bronchoalveolar lavage (BAL) galactomannan (GM) is commonly used to diagnose Aspergillus ‐related lung diseases. However, unlike serum GM, which measured in undiluted blood, BAL‐GM estimated using variable aliquots and cumulative volume of instillates during bronchoscopy. Objective Since different studies have reported varying diagnostic accuracy cut‐offs for CPA, we hypothesized that the total instillate ‘order/label’ significantly affects values, was evaluated as part...
Coronavirus disease 2019 (COVID-19) associated mucormycosis (CAM) was reported predominantly from India during the second wave of COVID-19 and has a high mortality rate. The present study aims to understand fungal community composition nasopharyngeal region CAM-infected individuals compare it with severe patients healthy controls. decoded by analyzing sequence homology internal transcribed spacer-2-(ITS-2) metagenomic DNA extracted upper respiratory samples. alpha-diversity indices were...
Prolific research on gender diversity invariably links it to the financial outcomes, responsible behaviour, stock movements and like. Very few studies have tried peep into actual board composition of companies know effective implementation status various impositions regulations introduced by legislators embrace equality seats. The current study attempts examine three main governance reforms that been recently Indian market regulator, Securities Exchange Board India (SEBI) Companies Act,...
Diphtheria, Tetanus, and whole-cell Pertussis (DTwP) vaccination-associated seizures form the commonest type of serious adverse event following immunization in India are an important reason for vaccine hesitancy. Our study explored genetic explanation DTwP or subsequent epilepsies.
Introduction. Invasive mucormycosis (IM) is a potentially fatal infection caused by fungi of the order Mucorales. Histopathology, culture, and radiology are mainstays diagnosis, but they not sufficiently sensitive, resulting in delayed diagnosis intervention. Recent studies have shown that PCR-based techniques can be promising way to diagnose IM.Hypothesis/Gap Statement. Early fungal infections using molecular diagnostic improve patient outcomes, especially invasive mucormycosis.Aim. The aim...
Abstract Background Chronic pulmonary aspergillosis (CPA) is known to complicate patients with post-tubercular lung disease. However, some evidence suggests that CPA might co-exist in newly-diagnosed tuberculosis (P.TB) at diagnosis and also develop during therapy. The objective of this study was confirm the presence newly diagnosed P.TB baseline end-of-therapy. Materials & Methods This prospective longitudinal included patients, followed up third month end-of-therapy symptom assessment,...
Unusual fungi, encountered infrequently in practice, present a significant diagnostic challenge, leading to potential delays diagnosis and treatment. This study aims describe number of cases, where infections were caused by rare yeast pathogens. Organisms isolated included Candida species, Geotrichum, Lodderomyces Trichosporon species. The mean duration the outcome patients from microbiological was 20 days. A total 3 succumbed their illness. shed light on varied clinical presentation
Invasive candidiasis (IC) in the hospitalized population is one of leading causes invasive fungal infections (IFIs). Microbiological diagnosis IC suffers due to poor sensitivity blood culture and relative inaccessibility more sensitive modalities. (1, 3)-β-D-glucan (BDG) a cell wall polysaccharide found range fungi. Various commercial assays are available based on various detection techniques. This study aimed assess diagnostic performance FungiXpert® Fungus BDG Detection Kit by Genobio...
Abstract Poster session 3, September 23, 2022, 12:30 PM - 1:30 Objectives To assess the diagnostic utility of MucorGenius® real-time PCR in tissue samples for diagnosis mucormycosis patients suspected having invasive (IM) during second wave COVID-19 pandemic. Methods A total 193 clinically cases IM presenting at our tertiary care center from May to July 2021 were included and defined as proven, probable, possible, or negative fungal disease (IFD) according EORTC/MSGERC guidelines. One sample...