- COVID-19 and healthcare impacts
- Antifungal resistance and susceptibility
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Infection Control in Healthcare
- CAR-T cell therapy research
- Bacterial Identification and Susceptibility Testing
- Parvovirus B19 Infection Studies
- SARS-CoV-2 and COVID-19 Research
- Respiratory Support and Mechanisms
- Medical and Biological Ozone Research
- Dermatological and COVID-19 studies
- Disaster Response and Management
- Biomedical Ethics and Regulation
- Infectious Diseases and Tuberculosis
- Cardiac Arrest and Resuscitation
- Biomedical and Engineering Education
- Infective Endocarditis Diagnosis and Management
- Fungal Infections and Studies
- Indoor Air Quality and Microbial Exposure
- Abdominal vascular conditions and treatments
- Drug-Induced Adverse Reactions
- Patient Safety and Medication Errors
- Insects and Parasite Interactions
- Medical Device Sterilization and Disinfection
All India Institute of Medical Sciences
2019-2024
Wayne State University
2023-2024
Detroit Medical Center
2024
All India Institute of Medical Sciences Bhopal
2020-2021
All India Institute of Medical Sciences Raipur
2020-2021
Marymount University
2020
Chimeric antigen receptor (CAR) T-cell therapy is an emerging therapeutic modality for relapsed and refractory hematological malignancies. Infectious complications following CAR are not well defined.
Abstract Background- The sharp uptick in the cases of mucormycosis background COVID19 pandemic is a cause concern and reasons it’s impact remains to be seen. We studied clinical characteristics patients with co-infection performed literature review. Methods- This retrospective study was conducted at tertiary centre India. All admitted were included, details obtained from hospital records. did review literatures using terms “SARS-CoV2” OR “COVID19” AND “Mucormycosis” “co-infection” on Pubmed...
Tele-healthcare to combat COVID-19 pandemic in developing countries: A proposed single centre and integrated national level model 1.
Re-purposing humanoid robots for patient care in COVID-19 pandemicTo the Editor, Increasing number of patients, shortage human resources and protective gears is alarming.Healthcare workers (HCW) are at highest risk infection.Around 20% HCW Italy over 3000 China infected. 1COVID-19 has led to a huge demand-supply mismatch Personal Protective Equipment (PPE). 2 Reducing on-floor HCW, thus reducing exposure need PPE appears be best strategy might useful achieve same. 3 Use robotics previous...
Objectives To study the histopathology of patients dying COVID-19 using post-mortem minimally invasive sampling techniques.
Invasive fungal infections are a constant threat to immunocompromised and critically ill patients. Healthcare workers caring for such patients act as conduits of transmission through their contaminated hands belongings causing nosocomial infections. Although bacterial contamination healthcare is known, our knowledge about carriage sparse. Among the fungi, candida species colonization known however it would be interesting know type on inanimate belongings.To study prevalence hands,...
Abstract Background Long COVID, or post-COVID-19 sequelae, is being seen in a growing number of patients reporting constellation symptoms, both pulmonary and extrapulmonary. Studies on COVID-19 recovered are scarce. Thus, there need to add granularity our existing knowledge about the course long-term effects infection. Aim To describe clinical details risk factors post-COVID sequelae North Indian population. Method This prospective observational study was conducted at tertiary healthcare...
Risk factors which led to the outbreak of COVID-19 associated Mucormycosis still remains elusive. Face masks can become contaminated by fungal spores that are present ubiquitously in environment. However exact burden such contamination is not known. Fifty patients who attended Employees Health Scheme facility a tertiary healthcare centre India were sampled direct impression smears on Sabouraud Dextrose Agar. Agar plates screened for any growth within five days after incubation. Growth was...
Linezolid-induced lactic acidosis is a rare, but life-threatening complication of commonly used drug. Patients present with persistent acidosis, hypoglycaemia, high central venous oxygen saturation and shock. Linezolid causes mitochondrial toxicity due to impaired oxidative phosphorylation. This evidenced by cytoplasmic vacuolations in the myeloid erythroid precursors bone marrow smear as illustrated our case. Discontinuation drug, administration thiamine haemodialysis reduces acid levels.
Chimeric antigen receptor (CAR) T-cell therapy has emerged as a novel therapeutic option for hematologic malignancies. Human immunodeficiency virus (HIV) nucleic acid amplification tests (NAATs) amplifying 5' long terminal repeat and gag genes cross-react with lentiviral vector-based CAR products. Cross-reactivity between products HIV NAATs may lead to false-positive test results.
Laparoscopic port-site infections, though infrequent, undermine the advantages provided by minimally invasive surgeries. Persistent nonhealing discharging sinuses, not responding to conventional antibiotic therapy, pose diagnostic and therapeutic challenges. Sizeable number of these infections is caused rapidly growing nontuberculous mycobacteria (NTM), diagnosing requires a high index suspicion. We present case laparoscopic cholecystectomy umbilical infection Mycobacterium senegalense ,...
Hepatosplenic space occupying lesions are usually labelled as metastasis. This case highlights the importance of thinking beyond malignancy and adopting a systematic approach when dealing with such that have plethora close differentials. tuberculosis is rare form extra pulmonary tuberculosis. Timely diagnosis treatment turned table from probable dismal prognosis to completely curable cause. We report an unusual case, which was provisionally malignancy, due isolated liver spleen involvement...
A rapid surge in cases during the COVID-19 pandemic can overwhelm any healthcare system. It is imperative to triage patients who would require oxygen and ICU care, predict mortality. Specific parameters at admission may help identifying them.A prospective observational study was undertaken a ward of tertiary care center. All baseline clinical laboratory data were captured. Patients followed till death or discharge. Univariable multivariable logistic regression used find predictors need for...
Vyas, Rahul MD; Damughatla, Anirudh DO; Keri, Vishakh C. MBBS, DM; Pyles, Josephine BS; Koleti, Pragna Joe Chintapally, Abhinav Reddy MBBS; Newman, Gretchen Snoeyenbos Lohia, Prateek MD Author Information
Introduction Cytomegalovirus (CMV) remains a serious opportunistic infection in hematopoietic cell transplant (HCT) and solid-organ (SOT) recipients. Traditional anti-CMV drugs are limited by toxicities the development of resistance. Letermovir maribavir newly approved antivirals for prevention treatment CMV.
MALDI-TOF-MS facilitates the identification of microorganisms from positive cultures in a timely and accurate manner. It eliminates necessity for application biochemicals operates on principle proteomics. decreases time required to report culture results. Prompt detection notification pathogen, prior disclosure antimicrobial susceptibilities, could potentially shorten duration until initial antibiotic adjustment is necessary, thereby influencing patients' clinical prognoses.
Detection of aspergillus by PCR is a helpful tool for early diagnosis. The test has excellent sensitivity and specificity with high negative predictive value. Well-accepted, standardized method DNA extraction testing to be adopted all commercial assays conclusive validation data are awaited in varied clinical settings. This perspective offers guidance utilizing while awaiting such data. Quantification PCR, species-specific identification detection resistance genetic markers future promise....